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fadE22

Victor ID 259
Gene Name fadE22
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887617
NCBI Protein GI 15610198
Locus Tag Rv3061c
Protein Accession NP_217577.1
Other Database IDs UniProtKB-ID: P95097_MYCTU
UniRef100: UniRef100_A5U775
UniRef90: UniRef90_A5U775
UniRef50: UniRef50_Q0RLX4
UniParc: UPI00000D600B
EMBL: AE000516
EMBL: BX842581
EMBL-CDS: AAK47480.1
EMBL-CDS: CAB06261.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000003350.
EnsemblGenome_TRS: EBMYCT00000003352
EnsemblGenome_PRO: EBMYCP00000003352
EnsemblGenome: EBMYCG00000072017.
EnsemblGenome_TRS: EBMYCT00000072022
EnsemblGenome_PRO: EBMYCP00000070081
GenomeReviews: AE000516_GR
GenomeRev
Taxonomy ID 83332
Gene Starting Position 3423261
Gene Ending Position 3425426
Gene Strand (Orientation) -
Protein Name PROBABLE ACYL-CoA DEHYDROGENASE FADE22
DNA Sequence 
>gi|57116681:3423261-3425426 Mycobacterium tuberculosis H37Rv, complete genome
CCTAGCTAATCAGGGGATCACGCGGCATGCCCAGGATCCGCTCGGCAATCTGATTGCGGGTCACCTCCGA
CGTGCCGCCGGCGATCGCCATGCCACGGGCGCCCATCACCGTTCGGCCAATCACCCTGCCGGGGCCGTCC
AGCAACGCAATCTCGGGCCCCCATAGCGCGGCCGCGATGGCGGCGCCCTCGATCATGTGCTCTGCCACTT
TGAGCTTGGTGATGTTGCCCTCCGGACCAGGGCCGGCTCCTTCGACGCTGCGAGCGGCACGGCGCAGGTT
CAGCAGCCGCAGTGCGTGATCCTCTGCGAGGAAAGCGCCGACTCGAATTGGGGCGCCCGCAAACGCATCT
GACCGCCGCTGGACCAATTGCACCAGCTTCGCCGCCATTGCTTCGTAGTACGAGCCACTGCCGCCGATGC
TGACCCGCTCGTTGCCCAGCGTTGCCCGCGCCACCGTCCACCCGGAGTTCGGCGCCCCGACAACGTCCTC
ATCGGGGACGAAGACATCGTTGAAGAACACCTCGTTGAATTCCGAGTCGCCGGTGATCTGCCGCAGCGGC
CGCACCTCGACACCGGGGGCCAACATGTCGATGATCACCGTGGTGATGCCAGCGTGTTTGGGGGCATCCG
GATCGGTACGCACGGTAGCCAGGCCACGCGCGCAGTACTGCGCTCCGCTGGTCCACACCTTTTGCCCGTT
GATCTTCCAGCCGCCCTCCACCCGAGTTGCGCGGGTCTTGACCGAGGCCGCGTCAGACCCCGCGTCAGGT
TCGGAGAACAGTTGGCACCATATCTCCTGCTGGCGCAGCGCTTTCTCGACGAATCTTTCAATCTGCCAAG
GCGTTCCGTGCTGAATCAGCGTCAAGATCACCCACCCGGTGATCGAGTAATCCGGGCGCTCGATGCCCGC
CGCGCTGAACTCTTCCTCGATCACCAACTGCTCCACCGCGCCCGCGGCACGACCCCACGGCCTGGGCCAA
TGCGGCATCACATAGCCCGTCTCGATCAGCTTGTCGCGCTGTGCATCCTTTTCCAGAGCAGCGATTTCAG
CGGCGTCCGAACGGATGCGGGCGCGCAGCTCCTCGGCCTGTGCCGGCAGGTCCAAGCTGATCGCCCGGGT
AACGCCAGCCGCGGTGCGCTCGAAAACGTCTCGGACGGGCGCATCACCGCCGAACAATCCCACGGTCACC
AACGCCCGGCGCAGATGCAGATGCGCGTCATGCTCCCAGGTAAAGCCAATACCGCCGTGCACCTGGATGT
TGAGCTCGGCATTGCGTGCATAGGCCGGAAACGCCAGGGCCGCAGCGACCGCGGCGGCCAGCCGAAACTG
CTCCTCATCCTCTGCTGCCGCACGCGCGGCATCCCAGACCGCGGCGATCGCCGACTCGGCGGCCACCAGC
ATGTTCGCGCAGTGATGCTTCACCGCTTGAAACGTGGCGATGGTACGGCCGAATTGCTGTCGCACCTTGG
CATAGGCCACGGCGCTGTCCACGCAGTCGGCCGCCCCACCGACGGCCTCGGCGGCCAGCAATGTGCGCGC
GCGGGCCAAAGCCGATTCATACGCACCAAGCAGGATGTCGTCGGTCGTGACGCGCACGTTGTCCAGGCGC
ACGCGGCCACTCCGCCGGGTCGGATCAAAGTTTTCCGGCACATCAACCGAGACGCCCTTGCGGCCGCGTT
CCAACACCAGCACGTCGTCACCGGCGGCAACCAACAGCAGCTCGGCAAGCCCGGCGCCCAACACGATTCC
CGCCTCACCGTCGGCAACACCGTCGGTAACCTGCACCTGACTATCCAGTCCCACACCCGCCGTCAGGGTT
CCGTCAATCAGCGCCGGCAACAGCCGTGCCCGTTGGTCATCAGTACCTTCTTTGGCGACCACCGCTGAGG
CGATCACGGTCGGCACAAACAGCCCCGGTGCCACCGCACGACCGAGCTCTTCGATCACCACCACAAGCTC
GGACAGGCCATAGCCAGAGCCACCGTGTCGCTCGTCGATATGCAGGCCGAGCCAGCCCAGCTCGGCGAGG
TTCTGCCAGAACGGCGGGCGGGCGTCCCCCGCCGCGTCCAGTGATGCACGCGCCGCCCAGCGCACCTTCT
GCGAAGTCAAGAACGCGCGAGCCACCCCGGAGAGCTCGCGATGGTCGTCGGTCAATGCAATACCCA
Protein Sequence 
>gi|15610198|ref|NP_217577.1| acyl-CoA dehydrogenase FadE22 [Mycobacterium tuberculosis H37Rv] MGIALTDDHRELSGVARAFLTSQKVRWAARASLDAAGDARPPFWQNLAELGWLGLHIDERHGGSGYGLSELVVVIEELGRAVAPGLFVPTVIASAVVAKEGTDDQRARLLPALIDGTLTAGVGLDSQVQVTDGVADGEAGIVLGAGLAELLLVAAGDDVLVLERGRKGVSVDVPENFDPTRRSGRVRLDNVRVTTDDILLGAYESALARARTLLAAEAVGGAADCVDSAVAYAKVRQQFGRTIATFQAVKHHCANMLVAAESAIAAVWDAARAAAEDEEQFRLAAAVAAALAFPAYARNAELNIQVHGGIGFTWEHDAHLHLRRALVTVGLFGGDAPVRDVFERTAAGVTRAISLDLPAQAEELRARIRSDAAEIAALEKDAQRDKLIETGYVMPHWPRPWGRAAGAVEQLVIEEEFSAAGIERPDYSITGWVILTLIQHGTPWQIERFVEKALRQQEIWCQLFSEPDAGSDAASVKTRATRVEGGWKINGQKVWTSGAQYCARGLATVRTDPDAPKHAGITTVIIDMLAPGVEVRPLRQITGDSEFNEVFFNDVFVPDEDVVGAPNSGWTVARATLGNERVSIGGSGSYYEAMAAKLVQLVQRRSDAFAGAPIRVGAFLAEDHALRLLNLRRAARSVEGAGPGPEGNITKLKVAEHMIEGAAIAAALWGPEIALLDGPGRVIGRTVMGARGMAIAGGTSEVTRNQIAERILGMPRDPLIS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1960I, under I: Lipid transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].