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rcK from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2587
Gene Name rcK from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1256230
NCBI Protein GI 17233474
Locus Tag PSLT009
Protein Accession NP_490501.1
Other Database IDs UniProtKB-ID: Q04817_SALTY
UniRef100: UniRef100_B5N6C0
UniRef90: UniRef90_B5N6C0
UniRef50: UniRef50_B5PK43
UniParc: UPI00000D2F6E
EMBL: M76130
EMBL: L08613
EMBL: AE006471
EMBL: AB576781
EMBL-CDS: AAA27201.1
EMBL-CDS: AAC36968.1
EMBL-CDS: AAL23513.1
EMBL-CDS: BAJ15295.1
RefSeq_NT: NC_003277.1
RefSeq_NT: NC_013437.1
RefSeq_NT: NC_014476.1
HSSP: P36546
GenomeReviews: AE006471_GR
KEGG: stm:PSLT009
NMPDR: fig|99287.1.peg.4434
HOGENOM: HBG685626
OMA: HGKAKVS
ProtClustDB: CLSK2518528
BioCyc: STYP99287:
Taxonomy ID 99287
Plasmid No pSLT
Gene Starting Position 4991
Gene Ending Position 5548
Gene Strand (Orientation) -
Protein Name resistance to complement killing
DNA Sequence 
>gi|17233403:4991-5548 Salmonella typhimurium LT2 plasmid pSLT, complete sequence
ATCAGAACCGGTAACCGACACCAACGTTAACGCCGTTCAGTTTCGCTGCGCCAACTTTACTTCCCTCATA
GCCCAGATCGATGACCACATTTTCCACCGGATTAAACTGTACGCCGGCTCCCCAGGCAAACCCCGTTCTG
CGCTCCGAACCCGTGAACCGCCCGTTGTATCCCGGCATGCTGATACGCTCTTTCACTTCAGCCCTGCCGG
TACCGGCACCGGCCAGTGCATACAGAGATACCAGCTCGTTCACACGGACAGCCGGACCCGCCATCAGCGA
CCAGTACGTCGCCTTCACATCATCACGCCAGCTCATTCCGCCAGGAATGCCACCGGACTCTCCGCGCTTA
CCTGACTGCCAACTGAACGACGCCATCAGTCCCAGCGGCGTCTGAGCCTCATAGCGGTATTTCAGGTTCA
CCCCACGGATATCCTTAAAATGCTCTATCCGGCTCTGGGCATATCCCACCGACACGGAATGGGTGTCAGC
CTGTGCCACCGGTACGGCAGCCAGCCCGGCTGCGGACAGCAGCAGTGAGGACAGAACGATTTTTTTCA
Protein Sequence 
>gi|17233474|ref|NP_490501.1| resistance to complement killing [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MKKIVLSSLLLSAAGLAAVPVAQADTHSVSVGYAQSRIEHFKDIRGVNLKYRYEAQTPLGLMASFSWQSGKRGESGGIPGGMSWRDDVKATYWSLMAGPAVRVNELVSLYALAGAGTGRAEVKERISMPGYNGRFTGSERRTGFAWGAGVQFNPVENVVIDLGYEGSKVGAAKLNGVNVGVGYRF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rck mutants reduces serum resistance and eukaryotic cell invasion (Cirillo et al., 1996).
COG COG3637M, under M: Cell wall/membrane/envelope biogenesis
References
Cirillo et al., 1996: Cirillo DM, Heffernan EJ, Wu L, Harwood J, Fierer J, Guiney DG. Identification of a domain in Rck, a product of the Salmonella typhimurium virulence plasmid, required for both serum resistance and cell invasion. Infection and immunity. 1996; 64(6); 2019-2023. [PubMed: 8675302].