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sopA from Salmonella enterica subsp. enterica serovar Typhimurium

Victor ID 2577
Gene Name sopA from Salmonella enterica subsp. enterica serovar Typhimurium
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium
NCBI Gene ID 7692994
NCBI Protein GI 228931267
Locus Tag pU302L_002
Genbank Accession AY333434
Protein Accession YP_194809
Taxonomy ID 90371
Plasmid No pU302L
Gene Starting Position 1958
Gene Ending Position 3124
Gene Strand (Orientation) +
Protein Name plasmid-partitioning protein SopA
Protein pI 5.62
Protein Weight 40683.37
Protein Length 388
Protein Note ORF.02; similar to NP_061425 SopA of plasmid F
DNA Sequence 
>gi|58383237:1958-3124 Salmonella enterica subsp. enterica serovar Typhimurium plasmid pU302L, complete sequence
AATGAAACTCATGGAAACACTTAACCAGTGCATAAACGCTGGTCATGAAATGACGAAGGCTATCGCCATT
GCACAGTTTAATGATGACAGCCCGGAAGCGAGGAAAATAACCCGGCGCTGGAGAATAGGTGAAGCAGCGG
ATTTAGTTGGGGTTTCTTCTCAGGCTATCAGAGATGCCGAGAAAGCAGGGCGACTACCGCACCCGGATAT
GGAAATTCGAGGACGGGTTGAGCAACGTGTTGGTTATACAATTGAACAAATTAATCATATGCGTGATGTG
TTTGGTACGCGATTGCGACGTGCTGAAGACGTATTTCCACCGGTGATCGGGGTTGCTGCCCATAAAGGTG
GCGTTTACAAAACCTCAGTTTCTGTTCATCTTGCTCAGGATCTGGCTCTGAAGGGGCTACGTGTTTTGCT
CGTGGAAGGTAACGACCCCCAGGGAACAGCCTCAATGTATCACGGATGGGTACCAGATCTTCATATTCAT
GCAGAAGACACTCTCCTGCCTTTCTATCTTGGGGAAAAGGACGATGTCACTTATGCAATAAAGCCCACTT
GCTGGCCTGGGCTTGACATTATTCCTTCCTGTCTGGCTCTGCACCGTATTGAAACTGAGTTAATGGGCAA
ATTTGATGAAGGTAAACTGCCCACCGATCCACACCTGATGCTCCGACTGGCCATTGAAACTGTTGCTCAT
GACTATGATGTCATAGTTATTGACAGCGCGCCTAACCTGGGTATCGGCACGATTAATGTCGTATGTGCTG
CTGATGTGCTGATTGTTCCCACGCCTGCTGAGTTGTTTGACTACACCTCCGCACTGCAGTTTTTCGATAT
GCTTCGTGATCTGCTCAAGAACGTTGATCTTAAAGGGTTCGAGCCTGATGTACGTATTTTGCTTACCAAA
TACAGCAATAGTAATGGCTCTCAGTCCCCGTGGATGGAGGAGCAAATTCGGGATGCCTGGGGAAGCATGG
TTCTAAAAAATGTTGTACGTGAAACGGATGAAGTTGGTAAAGGTCAGATCCGGATGAGAACTGTTTTTGA
ACAGGCCATTGATCAACGCTCTTCAACTGGTGCCTGGAGAAATGCTCTTTCTATTTGGGAACCTGTCTGC
AATGAAATTTTCGATCGTCTGATTAAACCACGCTGGGAGATTAGATA
Protein Sequence 
>gi|228931267|ref|YP_194809.2| plasmid-partitioning protein SopA [Salmonella enterica subsp. enterica serovar Typhimurium]
MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGEAADLVGVSSQAIRDAEKAGRLPHPDM
EIRGRVEQRVGYTIEQINHMRDVFGTRLRRAEDVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLL
VEGNDPQGTASMYHGWVPDLHIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGK
FDEGKLPTDPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDM
LRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGKGQIRMRTVFE
QAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sopA mutants induce significantly less fluid accumulation in bovine ligated ileal loops than the wild-type (Zhang et al., 2002).
References
Zhang et al., 2002: Zhang S, Santos RL, Tsolis RM, Stender S, Hardt WD, Bäumler AJ, Adams LG. The Salmonella enterica serotype typhimurium effector proteins SipA, SopA, SopB, SopD, and SopE2 act in concert to induce diarrhea in calves. Infection and immunity. 2002; 70(7); 3843-3855. [PubMed: 12065528].