Victors

boNT/B
Victor ID	2564
Gene Name	boNT/B
Sequence Strain (Species/Organism)	Clostridium botulinum B1 str. Okra
NCBI Gene ID	6030102
NCBI Protein GI	169834607
Locus Tag	CLD_A0068
Genbank Accession	AB232927
Protein Accession	YP_001693307
Other Database IDs	UniProtKB-ID: BXB_CLOBK UniRef100: UniRef100_B1INP5 UniRef90: UniRef90_B1INP5 UniRef50: UniRef50_B1INP5 UniParc: UPI000016EA76 EMBL: CP000940 EMBL-CDS: ACA46990.1 RefSeq_NT: NC_010379.1 GenomeReviews: CP000940_GR KEGG: cbb:CLD_A0068 HOGENOM: HBG419785 OMA: LKDFWGN ProtClustDB: CLSK912378 BioCyc: CBOT498213:CLD_A0068-MONOMER
Taxonomy ID	498213
Plasmid No	pCLD
Gene Starting Position	42316
Gene Ending Position	46191
Gene Strand (Orientation)	-
Protein Name	botulinum neurotoxin type B
Protein pI	4.97
Protein Weight	145339.54
Protein Length	1291
Protein Note	identified by similarity to SP:P10844; match to protein family HMM PF01742; match to protein family HMM PF07951; match to protein family HMM PF07952; match to protein family HMM PF07953
DNA Sequence	>gi\|169834533:42316-46191 Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence ATTATTCAGTCCACCCTTCATCTTTAGGAATAAACTGCCAATTACATCCCAATTTTAAATTATATGGTTT CCTTTTTACCTCTTTTAAGTACCATTTACTTATACAAAAATAATCTTTATACTCTTCAAATACAATTCCA GATTCGTAGAAACGATGAATACCAATCAATCCTATCTCATCAGTACTTTCTTCATCTTTTTTAAAAAGCA ACTGACAACTATATGTTGGCTGTTCATCATATTCTTTTATTTGTATAGTATTGTAAAACTCATCAGAATC ACTTATAGGAGCTAAAAACAATTTTTCTTCCTCTTTCTTAAAATATTTATAGGTATATACTCTCCACTCT TGATTTAAATTAAAAAAATCTAGATATATATAATCTTCTTTTCTAACTATATCATCATTTATAGATTGAG AATTTGACTTTCTTCTTATAATAAATTTTTCTCCAATATATAAATCTCTATAATTTATATATTTAGAATT TTGATTATATTTGCTACGTGTTAAAATTTCACCTACAGGTGAATCTTTCTTTAGTTTAATATATGAATTT TTATTCCCCGCATTAAACATATAATATTCTTTATTGTACATTAAAGGATTTCCCCAAAAATCTTTTAAAT ATTCGCTATATGATTGAATTTTATATCTTTCTTCAATATTTGATTGACTTAATTCCGTATTAAAAATACT GAAATATTTCATCCAAATAAATTGTGTTCTATCTATATCACCATCTAATTTAAATATTATTTCACCATTA GCAATAACTTCTCTTATATCTTTAATATCTGTATTTGATTCTAGCTTACCATTAATATAAATTTTAGCGT TATTCAAATTATTAGTAATAGTTACAAAAAACCATCTATTTATATACTCTGATATATCTTCTCTTATGTT ATATTCAAAAAATACCGATTTGGTTTTTCCATTTATATCAATTAAAGTCCATATTATCCTATTACCCCTA ATAGATATTTTCCAGCCCGAATTATTTTTCATACAATTAATTATTGTATATTCATTATGAATATAATTTT GTATACCATCATTCTTATATTTAGGTATTCTTATCCAAAAGCTAACGCTAAAATCAAGGAACACACTATT AAATATGATATTCTGATTTTGAGTCACTCTAATCTTACTATTTGCTGAACTAGTTAATTTAAATTGATTT TTATCATTAAGCTCGACTCCATCATATACCTCTACCTTTGCCCCATATCCTGATAAATCTATTAAATTAT TATCCTTATATCTTAAATTTAAGATAATATTATTTAAAATTTCGCTATTATATTTATTAAACATTTCTAT TAGTATTGTATCATTGGTATATATTGAAAGATCAAACGGCATAATGGTTTTCAAGTATTTATTTACTTTT GATTTTTCATATTCTGCACTTCCAATCAAATATAATTTATTTTCATCTATATAATTTAACAAATTTTTTT TGAGAGTATTATCAAAGTCTAGTAATTTTTCTACAGCTAATGGAATCATTTTTTTCATTAAATATGATAC AGAACATCCATTTATAAAATTATTTATATTATCTATAGCTTGGTTAATACCCTCATTAAGTTTAGAATTT ATATCATTAAAATCGATGTTAATATTTGACTTTTCTTTTTCAGAATATATATTATATCTGTATTTTATTA TTTCTTCCAATGCTTGTGCTTGATAATTTAAAGCCTTATACATTCCCTCTTTTATTGTATAAAATTGAGT ATTAACTGTTGAGAGCCATTGCGCTACTATTAATCCGTACATATCACTCCATTTTTCATTTCTTTTAGTT AAAGCATTATCTATTGTTTTAATAATTTTATTTTTATTGTCAATATATGATTCTAATAAAAAGGCTCCAA CTACAGGTATTAAAAGTTCTGGTATAAATTCTAGTAGAATACTGGCTCCTGCAATCTCAAAAGCATTTTC AAAATTTCCTTTAGCTGTTTCATTTCCTACATTTAAAGCTAATCCTATATAAGGAACAATTAGAGATATA TCTGCAATTTTATCCATAGTATTGCTTTTATTAGCTTCGATTACAAAATCATTTACTATCTGTTTCACCC AACCTGCAAATAATCCTGCTTCTACCACTTTATTAGCAGTTTTAATATAATCCATAGAAAAAAATGAATA AACTTTGTTAGAAAATAATAATGCATCATCAAATGAAGATGTTAAACTTATATCTCTTATATCTAGAGGA AATGTCTGAGAGTATAAATATTGAAAGATGGTATTTTCATCTGTAAAAATTTTTTTTATAGCGGGTTGTT TTTCATATACTGGAACATCTACATTAAAATCAGTAAGTGATTCTGTATTTTCACTTGGTAATTCTATTTT ACTTATTAAATCAGTATCTAAAATTAATTCATTTATAGGGAAGTCATTTTCTATATAATTACTCTGTGTA TTATATTCTATTCTTTCGTTTTTAGATAAATCATCTGAAAAACTATTTTTATCAGCTATAAAGAACAAAT CTTCATTATCAACATCAATACATATTCCTGGAGCTTTAACACTTTTACACATTTGTATCTTATATACAGC CAAATGCTCCTTGCTAATTTCTTCATAAGCTTGTTTATTTATAGCTTTATTCTGACCTCTATATTCTTTT TCCATATCTTTATCAGATATATTAAACCCTTCCTCTATAGTATAGATTTCATTATCTAATAAATTTTTTA TTTTTACTGGTGGTAAGGAATCACTAAAATAAGAAGCTCTAGTTTTTATTTTATAATTTTCTGCTATATT AGTTTCTGTAAAACCAAACATTAAGCTTTTATATAATTTATCAAAACTTTCTACATCTATACTATATTTT CCCTCAGAATCTTCAACGAATTTATATTTATCTTTAAATTTATTTTTATATATATTAATATTAATGTTAG GATCTGATATGCAAACTAAAACCTTGTTAAGTCTATCAACTATCCCTCTAAAATTTTGCAAAACTTTATC ATAGATACTTTTATCCGTAGAAGGAGTTATGATGCTGGGATCTTGTCCTCCAAATGTATATAGTTCTTCT GCCTGTATAGCATCTGTAGATTGCATAAAAAATTTTTTTTCATTTGGTACAATTGGTAAATCATCTACTT TAATGCCATATAATCCATGTAAAACATGTATAAGTTCATGCATTAATATCAAGGCTGGATCTGAAAAATA TCCACGTCTATTAAATATACTTGCGCCTTTGTTTTCTTGAACATTATTAAATACGCTTACATATTCTGGG CAAAACTTCATTTGCATTATACCCCCGAAGCCTTCCCTTGATGCAAAATGATTTTGTATACCTATATCTA TAGTCTCATTTTCATTTAAAACTGGCCCAGGTCCAAATATTATTAAATTTGCGAAAATACCTTTTTTTCG CTCCACTTCTCCTGGATTACTGATTAATTTATTAACAGTTACACTAGCAATGTTTGTGTTAAACTCTTCG AGTGGAACACGTCTATCTCCAAGATAAGGTATACCATTTATAATCATCTCTAATAACTTTTCACCCAATG GTTTTGATTTGATTCTATTAAATAACTTGATCATTGTTTGTAAAAATATATTCTTTTTATCATTAGTATT TAAGTAATCTGGATCATAATATTCACAAACATCTCTATTAAAAATACCGGAACTTTTATTAAAATCCTCA GGTTTATATCCAAAAGTATATCTTTCCGGTATTATCCAAATACGATCTGTGATTTTAAAAGCTTTATAAT ATCTCCCCGTACCTCTCGCAAATGGAGGCTCCATCATAATAATATTATTATTATCAATAGGATCATTATA ATTAAAATTATTTATTGTAACTGGCA
Protein Sequence	>gi\|169834607\|ref\|YP_001693307.1\| botulinum neurotoxin type B [Clostridium botulinum B1 str. Okra] MPVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDV CEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNK LISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENK GASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFFMQSTDAIQAEELYTFGGQDPSII TPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYK SLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQA YEEISKEHLAVYKIQMCKSVKAPGICIDVDNEDLFFIADKNSFSDDLSKNERIEYNTQSNYIENDFPINE LILDTDLISKIELPSENTESLTDFNVDVPVYEKQPAIKKIFTDENTIFQYLYSQTFPLDIRDISLTSSFD DALLFSNKVYSFFSMDYIKTANKVVEAGLFAGWVKQIVNDFVIEANKSNTMDKIADISLIVPYIGLALNV GNETAKGNFENAFEIAGASILLEFIPELLIPVVGAFLLESYIDNKNKIIKTIDNALTKRNEKWSDMYGLI VAQWLSTVNTQFYTIKEGMYKALNYQAQALEEIIKYRYNIYSEKEKSNINIDFNDINSKLNEGINQAIDN INNFINGCSVSYLMKKMIPLAVEKLLDFDNTLKKNLLNYIDENKLYLIGSAEYEKSKVNKYLKTIMPFDL SIYTNDTILIEMFNKYNSEILNNIILNLRYKDNNLIDLSGYGAKVEVYDGVELNDKNQFKLTSSANSKIR VTQNQNIIFNSVFLDFSVSFWIRIPKYKNDGIQNYIHNEYTIINCMKNNSGWKISIRGNRIIWTLIDING KTKSVFFEYNIREDISEYINRWFFVTITNNLNNAKIYINGKLESNTDIKDIREVIANGEIIFKLDGDIDR TQFIWMKYFSIFNTELSQSNIEERYKIQSYSEYLKDFWGNPLMYNKEYYMFNAGNKNSYIKLKKDSPVGE ILTRSKYNQNSKYINYRDLYIGEKFIIRRKSNSQSINDDIVRKEDYIYLDFFNLNQEWRVYTYKYFKKEE EKLFLAPISDSDEFYNTIQIKEYDEQPTYSCQLLFKKDEESTDEIGLIGIHRFYESGIVFEEYKDYFCIS KWYLKEVKRKPYNLKLGCNWQFIPKDEGWTE
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: BoNT/B toxoid without non-toxic components, which are generally associated with the toxin was used attenuated and used as a vaccine candidate (Yang et al., 2004)
References	*Yang et al., 2004:* Yang GH, Kim KS, Kim HW, Jeong ST, Huh GH, Kim JC, Jung HH. Isolation and characterization of a neutralizing antibody specific to internalization domain of Clostridium botulinum neurotoxin type B. Toxicon : official journal of the International Society on Toxinology. 2004; 44(1); 19-25. [PubMed: 15225558].


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boNT/B