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msbB from Yersinia pestis biovar Microtus str. 91001

Victor ID 2554
Gene Name msbB from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2766044
NCBI Protein GI 45441708
Locus Tag YP_1906
Protein Accession NP_993247.1
Other Database IDs UniProtKB-ID: Q7CIC3_YERPE
UniRef100: UniRef100_A4TJJ5
UniRef90: UniRef90_A1JRH3
UniRef50: UniRef50_P59198
UniParc: UPI00000DCD1B
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM85807.1
EMBL-CDS: AAS62124.1
EMBL-CDS: CAL20698.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO2063
KEGG: ypk:y2247
KEGG: ypm:YP_1906
HOGENOM: HBG730280
OMA: VPLFPVY
ProtClustDB: PRK08943
BioCyc
Taxonomy ID 229193
Gene Starting Position 2124082
Gene Ending Position 2125044
Gene Strand (Orientation) +
Protein Name lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase
DNA Sequence 
>gi|45439865:2124082-2125044 Yersinia pestis biovar Microtus str. 91001 chromosome, complete genome
CATGCACAAAGAAAAAAATGACGCAACTGGTTTTATTCCGGTATTTCAGAAAACCTTCCTCCATCCGCGT
TTCTGGGGGGTTTGGTTAGGTGCTGGAGCGATTGCGGCGCTCGCTTATATTCCACCCAAATTCCGTGATC
CTTTATTAGCTGGCATAGGGCGTCTCGCTGGGAAATTTGCTAAAAGCGCCCGTCGTCGCGCTCGTATTAA
TCTTCTTTATTGTATGCCTGAGTTACCCGAGTCTGAACGCGAACACATTATTGACCAGATGTTTGCTACC
GCAGCTCAACCGTTAATGATGATGGCAGAACTTTGTTTTCGTGATCCGAAAAAAGTGCTGACTCGCGTGC
ACTGGCATGGACAGGAAATACTGGATGAGCTGCAACAACAAGAGCGTAATGTTATTTTGTTGGTCCCCCA
TGCCTGGTCCATTGATATTCCGGCTATGCTGCTAGCGGAGCAGGGCAAGCCAGTTGCAGGTATGTTCCAT
CATCAACGTAATCCATTGGTGGACTATCTATGGAACAGTGCGCGTTTACATTTCGGTGGTCGGATCCATG
CCCGCGAAAGTGGCATCAAACCTTTTATCAGTTCAGTACGCCAAGGATTCTGGGGTTACTACTTACCTGA
TGAAGATTATGGTCCTGAGCAAAGTGAATTTGTTGATTTCTTCGCGACCTATAAGGCGACATTACCGGCA
ATAGGCCGTTTAATGAAAGTCTGCCGTGCGGCCATTGTACCGATGTTCCCTGTTTATAATTATAGAGAGC
ATCGTCTTGATATCTATATCCGTCCGCCAATGGATGATTTGGCGGATGCTGATGACGCCTATATTGCCCG
CCGGATGAATGAGGAAGTGGAGTTGTTGGTTAAGCCGAATCCAGAGCAATATACATGGATCTTAAAGCTG
TTAAAAACCCGGAAAGAGGGTGAAACCGAGCCCTATGTGCGCAAAGATCTTTA
Protein Sequence 
>gi|45441708|ref|NP_993247.1| lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase [Yersinia pestis biovar Microtus str. 91001] MHKEKNDATGFIPVFQKTFLHPRFWGVWLGAGAIAALAYIPPKFRDPLLAGIGRLAGKFAKSARRRARINLLYCMPELPESEREHIIDQMFATAAQPLMMMAELCFRDPKKVLTRVHWHGQEILDELQQQERNVILLVPHAWSIDIPAMLLAEQGKPVAGMFHHQRNPLVDYLWNSARLHFGGRIHARESGIKPFISSVRQGFWGYYLPDEDYGPEQSEFVDFFATYKATLPAIGRLMKVCRAAIVPMFPVYNYREHRLDIYIRPPMDDLADADDAYIARRMNEEVELLVKPNPEQYTWILKLLKTRKEGETEPYVRKDL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lpxM (msbB) mutant is attenuated in mice and guinea pigs (Feodorova et al., 2007).
COG COG1560M, under M: Cell wall/membrane/envelope biogenesis
References
Feodorova et al., 2007: Feodorova VA, Pan'kina LN, Savostina EP, Sayapina LV, Motin VL, Dentovskaya SV, Shaikhutdinova RZ, Ivanov SA, Lindner B, Kondakova AN, Bystrova OV, Kocharova NA, Senchenkova SN, Holst O, Pier GB, Knirel YA, Anisimov AP. A Yersinia pestis lpxM-mutant live vaccine induces enhanced immunity against bubonic plague in mice and guinea pigs. Vaccine. 2007; 25(44); 7620-7628. [PubMed: 17913308].