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purK from Yersinia pestis biovar Microtus str. 91001

Victor ID 2551
Gene Name purK from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2765634
NCBI Protein GI 45440690
Locus Tag YP_0847
Protein Accession NP_992229.1
Other Database IDs UniProtKB-ID: Q7CJZ2_YERPE
UniRef100: UniRef100_A4TP67
UniRef90: UniRef90_A4TP67
UniRef50: UniRef50_P43850
UniParc: UPI00000DC82F
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM84680.1
EMBL-CDS: AAS61106.1
EMBL-CDS: CAL21679.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
HSSP: P09029
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO3077
KEGG: ypk:y1102
KEGG: ypm:YP_0847
HOGENOM: HBG516369
OMA: LADRSEW
ProtClustDB: PR
Taxonomy ID 229193
Gene Starting Position 920274
Gene Ending Position 921338
Gene Strand (Orientation) -
Protein Name phosphoribosylaminoimidazole carboxylase ATPase subunit
DNA Sequence 
>gi|45439865:920274-921338 Yersinia pestis biovar Microtus str. 91001 chromosome, complete genome
GTTATAACTTATCTTGCGCCCAACGCAGTGCGTTCTGATACTCCGCGGGTAGCAAAGGAGCCAGTGCGGC
CAGGGATGCGCTTAATGCCGTACCCTCTGGATCGTTTAAATTCAGATGACCAACTTTGCGGCCTTCACGG
ACTTCTTTGTCGTACCAATGCAGATGTACTAATGGCAGAGACAGCCACTGAATATTTACTGGCGTGCCAA
TCAGATTAACCATCGCTGACGGGGTATTCACCACCGGCTGCGGCAGTGGCAGATCCAAAATGGCCCGCAG
ATGCAATTCGAACTGGCTAATTGATGCGCCGTTTTGTGTCCAGTGACCACTGTTATGAACGCGCGGGGCC
AGTTCATTGATCAACAGACGGTCGCCGACGATAAAACACTCCATCGCCATCACACCGACATAATTCAGCT
TATCCATAATGGCTGACAGCATTTTTTCGGCTTGCTGCTGTAGTTTGCTGTTGGGCTGTGGTAATGCCAC
GCTCATGCGCAAAATGCCATCTTCATGCAGATTATGGGTCAGTGGATAAAATACCGATTCACCTTGGTGG
CTGCGCGCGCCGATCAATGAGACTTCGCCGGAGAAGTTAATCCCCTGTTCGACAATACACTCGCCGTAAG
CATCGGGGGGTAAGGTACCCTGCTCACCAGGGCGTAAACGCCATTGACCCCGGCCGTCATAGCCGCCGAC
CCGCCGTTTTACGATGGCTAGCTCACCCAACGTGGCGAACACCTCAGGCCATTCACTGGCGCTGGATAAC
AATTGCCACGGCGCAGTTGCCAAACCCAAGCTATCGAGTAACTGCTTTTGGGGCAGACGATCTGCCAGAC
GTGGAAAAATATCGCGATTAACAAAAGCAGTATGGGTAGCTAATTCACGGGTTAAGGCGGTTTCCGGCCA
ACGTTCAATTTCAGCGGTGATCACACTGTGCTGATAAGGCACCGCTTCAGGTTCAGCATCTAAGCCGACG
GGATAAACCGCAATTCCCAGCGGTTCACCTGCCTGCCGCAGCATTCGCCCTAACTGGCCATTACCCAGTA
CACAAACTGGTTTCA
Protein Sequence 
>gi|45440690|ref|NP_992229.1| phosphoribosylaminoimidazole carboxylase ATPase subunit [Yersinia pestis biovar Microtus str. 91001] MKPVCVLGNGQLGRMLRQAGEPLGIAVYPVGLDAEPEAVPYQHSVITAEIERWPETALTRELATHTAFVNRDIFPRLADRLPQKQLLDSLGLATAPWQLLSSASEWPEVFATLGELAIVKRRVGGYDGRGQWRLRPGEQGTLPPDAYGECIVEQGINFSGEVSLIGARSHQGESVFYPLTHNLHEDGILRMSVALPQPNSKLQQQAEKMLSAIMDKLNYVGVMAMECFIVGDRLLINELAPRVHNSGHWTQNGASISQFELHLRAILDLPLPQPVVNTPSAMVNLIGTPVNIQWLSLPLVHLHWYDKEVREGRKVGHLNLNDPEGTALSASLAALAPLLPAEYQNALRWAQDKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purK mutant is attenuated in mice (Flashner et al., 2004).
COG COG0026F, under F: Nucleotide transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].