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sigD from Mycobacterium tuberculosis H37Rv

Victor ID 255
Gene Name sigD from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887594
Uniprot ID P66811
NCBI Protein GI 15610550
Locus Tag Rv3414c
Protein Accession NP_217931.1
Other Database IDs UniProtKB-ID: RPSD_MYCTU
UniRef100: UniRef100_P66812
UniRef90: UniRef90_P66812
UniRef50: UniRef50_P66812
UniParc: UPI0000134831
EMBL: BX842583
EMBL: AE000516
EMBL-CDS: CAB01009.1
EMBL-CDS: AAK47861.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002804
EnsemblGenome_TRS: EBMYCT00000002806
EnsemblGenome_PRO: EBMYCP00000002806
EnsemblGenome: EBMYCG00000070992
EnsemblGenome_TRS: EBMYCT00000070997
EnsemblGenome_PRO: EBMYCP00000069056
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 3833037
Gene Ending Position 3833675
Gene Strand (Orientation) -
Protein Name RNA polymerase sigma factor SigD
DNA Sequence 
>gi|57116681:3833037-3833675 Mycobacterium tuberculosis H37Rv, complete genome
TTCACGCATAGTCACCTGCCGCAACAATCTCGTCCTTCAGCCGCTGAAGTGCACGGTGTTGGGCCACCCG
GACCGCCCCCGTGGTGCTGCCGACGGCGGCGGCGGTCTCTTCCGCGGACAGGCCGACGACAACACGCAGA
ATGAGGATCTCGCGTTGCTTGGCCGGCAAGATCTCAAGCAATTCGTTCATCCGGGTGACCGAATCGGCCT
CGATGGCCATCTGCTCCGGGCCGGCGTCGGCTGACCAGCGCTCAGGAAGCGTTTCGGCGGGATAGGCCCG
GTCACGGCCGGCTGCCCGATGGGCGTCGGCAACCTTGTGCGCCGCGATGCCGTACAGAAACGCCAGGAAT
GGCCGGCCGCGGTCCCGATAGCGCGGCAGCGCCGTTATGGTGGCCAAGCACACCTCCTGTGCCACGTCAT
CTGCTGACAGGCCGCTCCGCTCGACCGTGCCGACTCGCGCTCGGCAATATCGCACGACGATCGGGCGGAT
GGTCTCCAGCACCTCCCGAAGCGCGTTCCGGTCTCCTGCCACGGCCTCCGCAACCACAGCGTCGAGACGT
TCCCCTTGCATTGTCATCGACGGCGATATCTCCAACGTTACGAAGCGGACACATCCCGGGCTAACTCCCG
GATCGACCA
Protein Sequence 
>gi|15610550|ref|NP_217931.1| ECF RNA polymerase sigma factor SigD [Mycobacterium tuberculosis H37Rv] MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEVCLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigD mutant is attenuated in human macrophages and mice (Calamita et al., 2005).
Predicted Interacting Host Protein A8MY43; B7Z207; B7Z7N6; D6RDN9; E9PCY5; E9PD65; F8W8L1; G3V384; G3V3E0; G3V419; H3BUV3; J3KTB7; O14874; P07900; P08238; P11388; Q02880; Q14568; Q15118; Q15119;
Q15120; Q16654; Q58FF6; Q9UHC1
COG COG1595K, under K: Transcription
References
Calamita et al., 2005: Calamita H, Ko C, Tyagi S, Yoshimatsu T, Morrison NE, Bishai WR. The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence. Cellular microbiology. 2005; 7(2); 233-244. [PubMed: 15659067].