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yfeA from Yersinia pestis biovar Microtus str. 91001

Victor ID 2543
Gene Name yfeA from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2764801
NCBI Protein GI 45442017
Locus Tag YP_2227
Protein Accession NP_993556.1
Other Database IDs UniProtKB-ID: YFEA_YERPE
UniRef100: UniRef100_Q56952
UniRef90: UniRef90_Q56952
UniRef50: UniRef50_Q56952
UniParc: UPI000013AE3E
EMBL: U50597
EMBL: AL590842
EMBL: AE009952
EMBL: AE017042
EMBL-CDS: AAC46147.1
EMBL-CDS: CAL21067.1
EMBL-CDS: AAM85464.1
EMBL-CDS: AAS62433.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
TCDB: 3.A.1.15.4
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO2439
KEGG: ypk:y1897
KEGG: ypm:YP_2227
HOGENOM: HB
Taxonomy ID 229193
Gene Starting Position 2475267
Gene Ending Position 2476238
Gene Strand (Orientation) +
Protein Name periplasmic-binding protein
DNA Sequence 
>gi|45439865:2475267-2476238 Yersinia pestis biovar Microtus str. 91001 chromosome, complete genome
CGTGATGTTAATTAAGAAAAAAAGTCCTTATCTCAAAATGATAGAACGACTAAACTCCCCTTTTCTACGG
GCTGCAGCCTTGTTTACAATTGTCGCATTCTCATCGCTGATCAGTACCGCTGCTTTAGCAGAAAATAATC
CCAGCGATACAGCCAAAAAATTCAAAGTTGTGACTACATTCACAATCATTCAGGATATTGCACAAAATAT
CGCCGGTGATGTTGCCGTGGTGGAGTCAATAACCAAGCCAGGCGCAGAGATTCATGACTATCAACCTACC
CCACGAGATATTGTAAAAGCACAGTCAGCAGACCTTATCTTATGGAATGGCATGAATCTGGAGCGTTGGT
TTGAGAAGTTCTTCGAAAGTATTAAAGATGTCCCGTCTGCCGTCGTGACCGCAGGTATTACACCCCTGCC
TATCCGTGAAGGCCCCTATAGCGGCATTGCCAACCCACATGCCTGGATGTCGCCATCAAATGCGCTAATA
TATATTGAGAATATCCGCAAAGCGTTAGTTGAACACGATCCCGCTCATGCAGAAACCTATAACCGTAACG
CGCAAGCCTATGCTGAAAAAATTAAGGCGCTAGATGCTCCACTGCGTGAGCGTTTATCTCGTATTCCTGC
GGAACAGCGTTGGTTAGTAACCAGTGAAGGGGCATTTAGTTATCTTGCCAAAGACTATGGTTTTAAAGAG
GTTTACTTATGGCCAATCAATGCAGAGCAACAAGGTATTCCGCAACAAGTTAGACACGTGATTGATATTA
TTCGCGAAAATAAAATTCCGGTGGTGTTTAGTGAGAGTACTATTTCCGACAAACCCGCCAAACAAGTGAG
TAAAGAAACCGGTGCACAATATGGCGGCGTGCTATATGTTGATTCTCTGTCGGGCGAAAAAGGCCCGGTC
CCCACTTACATCAGTTTAATTAACATGACTGTAGATACTATCGCTAAAGGATTCGGTCAATG
Protein Sequence 
>gi|45442017|ref|NP_993556.1| periplasmic-binding protein [Yersinia pestis biovar Microtus str. 91001] MMLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESITKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGFGQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yfeAB mutant is attenuated when given subcutaneously to mice and is avirulent when given to mice intravenously (Bearden and Perry, 1999).
COG COG0803P, under P: Inorganic ion transport and metabolism
References
Bearden and Perry, 1999: Bearden SW, Perry RD. The Yfe system of Yersinia pestis transports iron and manganese and is required for full virulence of plague. Molecular microbiology. 1999; 32(2); 403-414. [PubMed: 10231495].