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hspX from Mycobacterium tuberculosis H37Rv

Victor ID 254
Gene Name hspX from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887579
NCBI Protein GI 15609168
Locus Tag Rv2031c
Protein Accession NP_216547.1
Other Database IDs UniProtKB-ID: ACR_MYCTU
UniRef100: UniRef100_P0A5B8
UniRef90: UniRef90_P0A5B8
UniRef50: UniRef50_P0A5B8
UniParc: UPI000004A4BF
EMBL: S79751
EMBL: M76712
EMBL: BX842578
EMBL: AE000516
EMBL-CDS: AAB21317.1
EMBL-CDS: AAA25342.1
EMBL-CDS: CAA17245.1
EMBL-CDS: AAK46369.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002101
EnsemblGenome_TRS: EBMYCT00000002103
EnsemblGenome_PRO: EBMYCP00000002103
EnsemblGenome: EBMYCG00000069901
EnsemblGenome_TRS: EBMYCT00000069906
EnsemblGen
Taxonomy ID 83332
Gene Starting Position 2278497
Gene Ending Position 2278931
Gene Strand (Orientation) -
Protein Name HEAT SHOCK PROTEIN HSPX (ALPHA-CRSTALLIN HOMOLOG) (14 kDa ANTIGEN) (HSP16.3)
DNA Sequence 
>gi|57116681:2278497-2278931 Mycobacterium tuberculosis H37Rv, complete genome
GTCAGTTGGTGGACCGGATCTGAATGTGCTTTTCGGTTGGCTTCCCTTCCGAAACCGCCACCGACACAGT
AAGAATGCCCTTGTCGTAGGTGGCCTTAATGTCGTCCTCGTCAGCACCTACCGGCAGCGACACCGTGCGA
ACGAAGGAACCGTACGCGAATTCCGAGCGACCGTCGAAGTCCTTCTGCTCGGTGCGCTCGGCCTTGATGG
TCAGCTGACCATCGCGGACCATAATGTCGACGTCCTTGTCGGGGTCGACCCCGGGAAGCTCCGCGCGTAC
CTCGTAGCGCCCCTCTTTCATCTCGTCTTCCAGCCGCATCAACCGGGTGTCGAAGGTGGGCCGGAGTCCG
GCGAATGACGGGAAGGCCGCGAACAGCTCAGAAAACTCGGGGAAGAGGGACCGCGGGTGGCGCTGAACGG
GAAGGGTGGTGGCCA
Protein Sequence 
>gi|15609168|ref|NP_216547.1| alpha-crystallin [Mycobacterium tuberculosis H37Rv] MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMKEGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDGRSEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGKPTEKHIQIRSTN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hspX mutant is attenuated in murine macrophages and THP-1 cells (Yuan et al., 1998).
COG COG0071O, under O: Posttranslational modification, protein turnover, chaperones
References
Yuan et al., 1998: Yuan Y, Crane DD, Simpson RM, Zhu YQ, Hickey MJ, Sherman DR, Barry CE 3rd. The 16-kDa alpha-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 1998; 95(16); 9578-9583. [PubMed: 9689123].