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ugd

Victor ID 2536
Gene Name ugd
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2763750
NCBI Protein GI 45441774
Locus Tag YP_1973
Protein Accession NP_993313.1
Other Database IDs UniProtKB-ID: Q8D0G7_YERPE
UniRef100: UniRef100_A4TJ98
UniRef90: UniRef90_A4TJ98
UniRef50: UniRef50_O86422
UniParc: UPI00000E44D1
EMBL: AE009952
EMBL: AE017042
EMBL-CDS: AAM85709.1
EMBL-CDS: AAS62190.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
HSSP: P11759
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
KEGG: ypk:y2147
KEGG: ypm:YP_1973
HOGENOM: HBG400967
ProtClustDB: CLSK889126
BioCyc: YPES187410:Y2147-MONOMER
Taxonomy ID 229193
Gene Starting Position 2194166
Gene Ending Position 2195539
Gene Strand (Orientation) +
Protein Name putative nucleotide sugar dehydrogenase
DNA Sequence 
>gi|45439865:2194166-2195539 Yersinia pestis biovar Microtus str. 91001 chromosome, complete genome
ATTGAATTTCAACTCGGAGATCGAGCGAATGAAGGTTACGGTTTTTGGTATTGGTTATGTGGGACTTGTT
CAAGCTACAGTGCTTGCCGAGGTGGGGCATGATGTCCTTTGTATCGATATTGATGCTAATAAAGTTGCCG
ATTTGAAAAAAGGCCGTATTGCTATTTTTGAGCCGGGCTTGGCTCCGTTGGTCAAAGAAAACTATGAGGC
AGGCAGATTACAGTTTTCAACAGATGCGCAAGCTGGTGTGGCACATGGCGTCATTCAATTTATTGCTGTG
GGTACACCTCCTGATGAAGACGGTGCTGCCGATCTTAAATATGTCCTTGATGTGGCCAGTACCATTGGCA
CGTATATGGACTCACCTAAGGTCATTATCGATAAATCTACAGTGCCCGTGGGGACAGCGGATAAAGTACA
TCAAGTTATACAAGCTATTTTGGAGCAGCGCGGTGAGAAGATAGATTTTAGTGTGGTATCAAATCCTGAG
TTTTTAAAAGAGGGGGCCGCAGTTGCTGATTGTAAACGGCCTGAACGTATTGTTATTGGTATTGATACGG
ATGACAGTGGTGCTCTAGAGTTAATCAGTGAATTATACGAACCTTTTAATCGAAATCATGATCGTATGCT
AGTAATGGATATCCGTAGTGCAGAACTGACAAAGTATGCTGCAAACGGCATGCTGGCAACGAAAATAAGT
TTCATGAATGAGATTGCTAATATTGCTGAGCGATTAGGGGCTGATATCGAAAAAGTTCGACAGGGCATCG
GTTCCGATTCACGTATTGGATACCATTTCATTTATTCTGGTTGTGGTTATGGGGGGTCTTGTTTCCCAAA
AGACATCCAAGCATTAATTCGTACTGCAGAAGATAAGGGTTATAAGCCCCAGCTATTGCAGGCTGTCGAG
CAAATCAATAATCAGCAGAAGTATAAGTTAACTGAATTCATTAAAAGTCATTTTAATTCGCAGTTAGCTG
GAAAAACATTTGCTGTCTGGGGATTGGCCTTTAAGCCCAACACCGATGATATGCGTGAGGCACCGAGCCG
TGTGGTAATGGAATCATTGTGGGAAGCCGGGGCTACAATTCAAGCATACGATCCCGAAGCAATGGATGAG
ACGCAACGCATTTATGGTGCAAGAGATGATTTGAGATTAATGGGGACTAAAGAGTCTGCATTACAGGGAG
CTGATGCCTTGATTATTTGTACTGAATGGCAAAGTTTTCGTGCTCCAGATTTTGATATGATCAAGTCAAG
GTTAAAGCACCCTGTTATTTTTGATGGGCGTAATTTGTACGATCCAGAACGCCTAAATAGTCGTGGGTTC
ACTTATTATGGAATTGGGCGTGGTGTTTCGATTAATCTATCATA
Protein Sequence 
>gi|45441774|ref|NP_993313.1| nucleotide sugar dehydrogenase [Yersinia pestis biovar Microtus str. 91001] MNFNSEIERMKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAIFEPGLAPLVKENYEAGRLQFSTDAQAGVAHGVIQFIAVGTPPDEDGAADLKYVLDVASTIGTYMDSPKVIIDKSTVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGAAVADCKRPERIVIGIDTDDSGALELISELYEPFNRNHDRMLVMDIRSAELTKYAANGMLATKISFMNEIANIAERLGADIEKVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQKYKLTEFIKSHFNSQLAGKTFAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQAYDPEAMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSFRAPDFDMIKSRLKHPVIFDGRNLYDPERLNSRGFTYYGIGRGVSINLS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ugd mutant had defects in intracellular survival in macrophages (Grabenstein et al., 2006).
COG COG1004M, under M: Cell wall/membrane/envelope biogenesis
References
Grabenstein et al., 2006: Grabenstein JP, Fukuto HS, Palmer LE, Bliska JB. Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages. Infection and immunity. 2006; 74(7); 3727-3741. [PubMed: 16790745].