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mmpL7 from Mycobacterium tuberculosis H37Rv

Victor ID 252
Gene Name mmpL7 from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887548
NCBI Protein GI 15610079
Locus Tag Rv2942
Protein Accession NP_217458.1
Other Database IDs UniProtKB-ID: MMPL7_MYCTU
UniRef100: UniRef100_P65371
UniRef90: UniRef90_P65371
UniRef50: UniRef50_P65371
UniParc: UPI0000036B91
EMBL: BX842581
EMBL: AE000516
EMBL-CDS: CAB06107.1
EMBL-CDS: AAK47339.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 2.A.6.5.2
EnsemblGenome: EBMYCG00000003295
EnsemblGenome_TRS: EBMYCT00000003297
EnsemblGenome_PRO: EBMYCP00000003297
EnsemblGenome: EBMYCG00000070236
EnsemblGenome_TRS: EBMYCT00000070241
EnsemblGenome_PRO: EBMYCP00000068300
GenomeReviews: AE000516
Taxonomy ID 83332
Gene Starting Position 3285069
Gene Ending Position 3287831
Gene Strand (Orientation) +
Protein Name CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL7
DNA Sequence 
>gi|57116681:3285069-3287831 Mycobacterium tuberculosis H37Rv, complete genome
GATGCCTAGTCCGGCTGGCCGTCTACACAGAATTCGGTATATCCGTTTGAAAAAGTCCTCCCCGGACTGC
CGCGCCACCATCACCAGCGGGTCAGCCGACGGTCAGCGAAGGTCACCCCGGCTCACCAACCTGCTCGTCG
TCGCCGCCTGGGTTGCCGCGGCGGTGATCGCAAATCTGCTTCTCACGTTCACGCAAGCAGAACCGCACGA
CACCAGCCCGGCGCTGCTGCCACAAGATGCCAAGACAGCCGCCGCCACCAGCCGGATTGCGCAGGCTTTC
CCCGGCACCGGTAGCAACGCTATCGCCTATCTCGTCGTGGAAGGCGGCAGCACGCTTGAGCCGCAGGACC
AGCCTTACTACGACGCCGCCGTCGGTGCCCTGCGCGCCGACACCCGCCACGTGGGATCCGTCCTCGACTG
GTGGTCAGATCCCGTCACCGCCCCGCTGGGAACCAGCCCCGACGGCCGCTCCGCTACGGCCATGGTGTGG
CTGCGGGGCGAGGCGGGCACCACCCAAGCTGCCGAATCCCTCGATGCCGTCCGATCGGTGCTGCGCCAGT
TACCGCCCAGTGAGGGGCTTCGCGCCAGCATCGTGGTCCCGGCAATCACCAACGACATGCCGATGCAGAT
AACCGCCTGGCAGAGCGCGACGATCGTGACCGTTGCGGCGGTGATCGCCGTCCTACTGCTGCTGCGGGCG
CGCCTGTCGGTGCGGGCCGCGGCGATCGTGCTGCTGACCGCGGACTTGTCGCTTGCGGTGGCCTGGCCGC
TGGCCGCGGTGGTGCGGGGACACGATTGGGGAACCGATTCGGTATTTTCTTGGACGCTGGCCGCGGTCCT
GACGATCGGAACCATCACCGCAGCCACCATGCTGGCCGCGCGGCTCGGGTCCGACGCAGGTCATTCGGCC
GCGCCCACATACCGCGACAGCCTGCCCGCGTTCGCCCTGCCCGGGGCGTGTGTCGCCATATTCACCGGCC
CGCTGCTGCTGGCCCGAACCCCAGCGCTGCACGGAGTTGGCACTGCCGGGCTAGGTGTCTTTGTGGCACT
TGCGGCTTCGTTGACGGTGCTGCCTGCCCTGATCGCGCTTGCCGGAGCGTCACGGCAGTTACCGGCACCA
ACCACGGGTGCCGGCTGGACAGGCCGGTTGTCGCTACCCGTCTCTTCTGCTTCGGCCCTGGGCACAGCGG
CAGTGCTGGCGATCTGCATGCTACCCATCATCGGGATGCGGTGGGGTGTGGCCGAGAACCCGACAAGGCA
AGGCGGCGCACAAGTCCTTCCGGGGAATGCGCTTCCCGATGTGGTGGTGATCAAATCCGCTCGGGACCTG
AGGGACCCAGCCGCGCTCATCGCCATCAACCAGGTCAGCCACCGTCTGGTGGAGGTTCCCGGTGTGCGCA
AGGTGGAGTCGGCGGCATGGCCGGCCGGTGTCCCGTGGACCGACGCCTCGCTCAGTTCCGCGGCCGGCAG
GCTCGCCGACCAGCTGGGTCAGCAGGCCGGATCGTTCGTGCCGGCGGTGACTGCGATCAAATCGATGAAG
TCCATAATCGAACAGATGAGCGGCGCGGTCGACCAACTGGACAGCACCGTGAACGTGACTCTCGCCGGGG
CAAGGCAAGCACAGCAATACCTCGATCCCATGCTCGCCGCCGCGCGGAACCTCAAAAACAAAACCACCGA
ACTGTCGGAATACCTGGAAACGATCCACACCTGGATTGTCGGCTTCACAAACTGCCCCGACGACGTCCTG
TGCACGGCCATGCGCAAGGTCATTGAACCCTACGACATCGTGGTCACCGGCATGAACGAGCTGTCCACTG
GCGCCGACCGCATCTCCGCGATATCGACACAGACAATGAGCGCGTTGTCCTCGGCACCGCGGATGGTGGC
GCAGATGCGGTCGGCGCTAGCACAGGTGCGCTCGTTCGTACCCAAGCTGGAAACAACCATCCAGGACGCC
ATGCCGCAAATAGCGCAGGCGTCGGCGATGCTGAAGAATCTCAGCGCCGATTTCGCCGATACCGGTGAGG
GCGGCTTCCACCTGTCCAGGAAGGACCTGGCGGACCCGTCGTACCGGCACGTACGGGAATCGATGTTCTC
GTCAGACGGAACCGCCACCCGGCTGTTCCTCTATTCTGACGGACAACTGGACCTTGCTGCGGCAGCACGC
GCGCAGCAGCTCGAGATCGCCGCGGGCAAGGCGATGAAATACGGAAGCCTGGTCGACAGCCAGGTCACGG
TGGGTGGGGCCGCGCAAATAGCCGCGGCTGTCCGCGATGCCCTCATCCACGATGCTGTGCTACTGGCCGT
TATCTTGCTCACGGTAGTGGCTCTGGCCAGCATGTGGCGCGGTGCCGTCCACGGTGCTGCGGTTGGCGTG
GGTGTGCTGGCCTCTTACCTCGCCGCCCTGGGGGTCTCGATTGCACTGTGGCAACACCTACTGGATCGCG
AGCTCAACGCCTTGGTCCCGCTGGTGTCGTTCGCCGTCCTCGCTTCGTGCGGCGTCCCGTATCTCGTTGC
CGGCATCAAAGCCGGTCGTATCGCCGACGAGGCAACGGGTGCGCGGTCCAAGGGGGCGGTATCCGGGCGG
GGAGCGGTTGCGCCGCTTGCGGCGCTCGGTGGCGTATTCGGCGCTGGCCTGGTGCTGGTGTCGGGAGGTT
CCTTCAGCGTGCTCAGTCAGATTGGCACGGTTGTTGTGCTCGGTCTGGGCGTGCTGATCACGGTGCAGCG
AGCGTGGCTTCCGACCACGCCAGGGCGGCGTTG
Protein Sequence 
>gi|15610079|ref|NP_217458.1| transmembrane transport protein MmpL7 [Mycobacterium tuberculosis H37Rv] MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAAAIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTELSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mmpL7 mutant is attenuated in mice (Cox et al., 1999).
COG COG2409R, under R: General function prediction only
References
Cox et al., 1999: Cox JS, Chen B, McNeil M, Jacobs WR Jr. Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice. Nature. 1999; 402(6757); 79-83. [PubMed: 10573420].