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yopK from Yersinia pestis KIM 10

Victor ID 2519
Gene Name yopK from Yersinia pestis KIM 10
Sequence Strain (Species/Organism) Yersinia pestis KIM 10
NCBI Gene ID 1149323
NCBI Protein GI 31795502
Locus Tag Y0066
Protein Accession NP_857959.1
Other Database IDs UniProtKB-ID: O68704_YERPE
UniRef100: UniRef100_O68704
UniRef90: UniRef90_P27474
UniRef50: UniRef50_P27474
UniParc: UPI00000D6079
EMBL: AF053946
EMBL: AF074612
EMBL-CDS: AAC62583.1
EMBL-CDS: AAC69810.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
OMA: KGNIELY
ProtClustDB: CLSK862117
Taxonomy ID 187410
Plasmid No pCD1
Gene Starting Position 48935
Gene Ending Position 49483
Gene Strand (Orientation) +
Protein Name Yop targeting protein
DNA Sequence 
>gi|31795449:48935-49483 Yersinia pestis KIM plasmid pCD1, complete sequence
TATGTTTATTAAAGATACTTATAACATGCGTGCTTTATGTACCGCTCTTGAACAGTCGGCTCCTGATACA
ATAATAAATACATCTAAAGAAGAAAATAACAGTTACTACTGCGCTACTGCTCATTTACTGAGAACGGATG
TTTGTTCATTGGTCAATAGAGTAGGGATTGAACCACTTAAAAGTGGATCAATATTATCTACTTTAGAAGA
GTTATGGCAGGCTGTTGGTATAGTATATCGCTTATACGAATGGCAACATGTCAGCGATATTGACACCAAT
TTTAAGAAACTACCCAATAATTCTGATTTTGGTCTTGTGTTTTCTGTATTAGATTGTGATATAGAGTATG
TGTTCATAGGGAAAAAAGACAGTGAAGGGAATATAGAATTTTATGATCCGAAAAACTCTCTACTTATAGA
GAATGATGACATAAAAAAATATTTATATGATGAAGATTTTCATCGTTTTTGTATTATGCTGATCATCTCT
AAATCTGAGTTGGAGGAATTGAGTCGCGAATCCTGCGATCAAGAATGTATTATGGGATG
Protein Sequence 
>gi|31795502|ref|NP_857959.1| Yop targeting protein [Yersinia pestis] MFIKDTYNMRALCTALEQSAPDTIINTSKEENNSYYCATAHLLRTDVCSLVNRVGIEPLKSGSILSTLEELWQAVGIVYRLYEWQHVSDIDTNFKKLPNNSDFGLVFSVLDCDIEYVFIGKKDSEGNIEFYDPKNSLLIENDDIKKYLYDEDFHRFCIMLIISKSELEELSRESCDQECIMG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopK mutant has an increased LD50 dose in mice, and infected mice died after 5 days as compared to mice infected with the wild type died after just 3 days (Straley and Bowmer, 1986).
References
Straley and Bowmer, 1986: Straley SC, Bowmer WS. Virulence genes regulated at the transcriptional level by Ca2+ in Yersinia pestis include structural genes for outer membrane proteins. Infection and immunity. 1986; 51(2); 445-454. [PubMed: 3002984].