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yopM from Yersinia pestis KIM 10

Victor ID 2517
Gene Name yopM from Yersinia pestis KIM 10
Sequence Strain (Species/Organism) Yersinia pestis KIM 10
NCBI Gene ID 1149317
NCBI Protein GI 31795498
Locus Tag Y0059
Protein Accession NP_857953.1
Other Database IDs UniProtKB-ID: YOPM_YERPE
UniRef100: UniRef100_P17778
UniRef90: UniRef90_P17778
UniRef50: UniRef50_P17778
UniParc: UPI000013BCB1
EMBL: AF074612
EMBL: AF053946
EMBL: AL117189
EMBL: AE017043
EMBL-CDS: AAC69806.1
EMBL-CDS: AAC62580.1
EMBL-CDS: CAB54903.1
EMBL-CDS: AAS58577.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
RefSeq_NT: NC_005813.1
PDB: 1G9U
PDB: 1JL5
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.26c
KEGG: ypm:YP_pCD60
HOGENOM: HBG758074
OMA:
Taxonomy ID 187410
Plasmid No pCD1
Gene Starting Position 43480
Gene Ending Position 44709
Gene Strand (Orientation) +
Protein Name Yop targeted effector protein
DNA Sequence 
>gi|31795449:43480-44709 Yersinia pestis KIM plasmid pCD1, complete sequence
TATGTTCATAAATCCAAGAAATGTATCTAATACTTTTTTGCAAGAACCATTACGTCATTCTTCTAATTTA
ACTGAGATGCCGGTTGAGGCAGAAAATGTTAAATCTAAGACTGAATATTATAATGCATGGTCGGAATGGG
AACGAAATGCCCCTCCGGGGAATGGTGAACAGAGGGAAATGGCGGTTTCAAGGTTACGAGATTGCCTGGA
CCGACAAGCCCATGAGCTAGAACTAAATAATCTGGGGCTGAGTTCTTTGCCGGAATTACCTCCGCATTTA
GAGAGTTTAGTGGCGTCATGTAATTCTCTTACAGAATTACCGGAATTACCGCAGAGCCTGAAATCACTTC
TAGTTGATAATAACAATCTGAAGGCATTATCCGATTTACCACCTTTACTGGAATATTTAGGTGTCTCTAA
TAATCAGCTGGAAAAATTGCCAGAGTTGCAAAACTCGTCCTTCTTGAAAATTATTGATGTTGATAACAAT
TCACTGAAAAAACTACCTGATTTACCTCCTTCACTGGAGTTTATTGCTGCTGGTAATAATCAGCTGGAAG
AATTGCCAGAGTTGCAAAACTTGCCCTTCTTGACTGCGATTTATGCTGATAACAATTCACTGAAAAAACT
ACCTGATTTACCTCTTTCACTGGAATCTATTGTTGCTGGTAATAATATTCTGGAAGAATTGCCAGAGTTG
CAAAACTTGCCCTTCTTGACTACGATTTATGCTGATAACAATTTACTGAAAACATTACCCGATTTACCCC
CTTCCCTGGAAGCACTTAATGTCAGAGATAATTATTTAACTGATCTGCCAGAATTACCGCAGAGTTTAAC
CTTCTTAGATGTTTCTGAAAATATTTTTTCTGGATTATCGGAATTGCCACCAAACTTGTATTATCTCAAT
GCATCCAGCAATGAAATAAGATCCTTATGCGATTTACCCCCTTCACTGGAAGAACTTAATGTCAGTAATA
ATAAGTTGATCGAACTGCCAGCGTTACCTCCACGCTTAGAACGTTTAATCGCTTCATTTAATCATCTTGC
TGAAGTACCTGAATTGCCGCAAAACCTGAAACAGCTCCACGTAGAGTACAACCCTCTGAGAGAGTTTCCC
GATATACCTGAGTCAGTGGAAGATCTTCGGATGAACTCTGAACGTGTAGTTGATCCATATGAATTTGCTC
ATGAGACTACAGACAAACTTGAAGATGATGTATTTGAGTA
Protein Sequence 
>gi|31795498|ref|NP_857953.1| Yop targeted effector protein [Yersinia pestis] MFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDIPESVEDLRMNSERVVDPYEFAHETTDKLEDDVFE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopM mutant is attenuated in mice compared to the wild type (Leung et al., 1990).
References
Leung et al., 1990: Leung KY, Reisner BS, Straley SC. YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice. Infection and immunity. 1990; 58(10); 3262-3271. [PubMed: 2401564].