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lcrF from Yersinia pestis KIM 10

Victor ID 2512
Gene Name lcrF from Yersinia pestis KIM 10
Sequence Strain (Species/Organism) Yersinia pestis KIM 10
NCBI Gene ID 1149292
NCBI Protein GI 31795474
Locus Tag Y0032
Protein Accession NP_857928.1
Other Database IDs UniProtKB-ID: LCRF_YERPE
UniRef100: UniRef100_P28808
UniRef90: UniRef90_A1JU91
UniRef50: UniRef50_A1JU91
UniParc: UPI000012E2B3
EMBL: M86690
EMBL: AF074612
EMBL: AF053946
EMBL: AL117189
EMBL: AE017043
EMBL-CDS: AAA25558.1
EMBL-CDS: AAC69782.1
EMBL-CDS: AAC62554.1
EMBL-CDS: CAB54926.1
EMBL-CDS: AAS58553.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
RefSeq_NT: NC_005813.1
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.49
KEGG: ypm:YP_pCD34
HOGENOM: H
Taxonomy ID 187410
Plasmid No pCD1
Gene Starting Position 23906
Gene Ending Position 24721
Gene Strand (Orientation) -
Protein Name transcriptional regulator
DNA Sequence 
>gi|31795449:23906-24721 Yersinia pestis KIM plasmid pCD1, complete sequence
TTTAGCCTGTGGTTGCTATTTTAGTAAGACGGGCTTGGCTTGGAGTGCATCCGAAGCGACGTCGATAACT
TTGAGTGAAATAAGACTGACTCGAGAACCCCGCTTCCATGGCAATATCAACAATACTCATCTTACCATTA
AGAAGTAATTGGTGAGCATAGAGAATACGTCGCTCGCTTATCCAGGCGCGTGGTGAAATGCCATAAACTG
TACCAAACAGTTCTTTGAATGTGGTTAATCCCATGCCGAATTCTCGCGCAAATTTGCTTAGCTTCCACCC
TTGTAGATAATTTTCCTCCATAAATTTTTGCAACCGTTCTTCTGGGCGGTTGCCTAAATGGCGCAGAGCC
GAGAGAAATAAAGTCCCTTGCGAGCTAAAGGCAAGCAAAAGCAGTAATTCCTCAATACGCAGTTGCGTTA
ATACTGACGGAAAATCACTCCGTTCCAATATGGCACATAGATTTTGAATGGATTGTGATAATATTGGTGA
AATATTAAAAATTAACAATGGTTTGGGTGTGGAGTTGTCTCGTCCAATTTCACTAAGCAAAGAACCAAAG
CGATGCAAAAAAGTACTCAAAAAACTGCCGGGTAATGGAATCCAAAGTAATTGGCAGGGTTCTTTTGTAC
CACATCGAACAGCATAGCTGCCACGACGCAAAAACAGCATATTCCCCTCATCTAAATCATATGTCTGACC
GCTGCTCTGCCATGAAATCTGACCTTGCAAAAGAATATATAGGCCATCTTGTGAATGCTCAACAACCTTA
AATATAGGTGTGACCCATTCTAATTTAATAATCTCTAGTGATGCCA
Protein Sequence 
>gi|31795474|ref|NP_857928.1| LCR activator [Yersinia pestis] MASLEIIKLEWVTPIFKVVEHSQDGLYILLQGQISWQSSGQTYDLDEGNMLFLRRGSYAVRCGTKEPCQLLWIPLPGSFLSTFLHRFGSLLSEIGRDNSTPKPLLIFNISPILSQSIQNLCAILERSDFPSVLTQLRIEELLLLLAFSSQGTLFLSALRHLGNRPEERLQKFMEENYLQGWKLSKFAREFGMGLTTFKELFGTVYGISPRAWISERRILYAHQLLLNGKMSIVDIAMEAGFSSQSYFTQSYRRRFGCTPSQARLTKIATTG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lcrF mutant is attenuated in mice (Flashner et al., 2004).
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].