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yscH from Yersinia pestis biovar Microtus str. 91001

Victor ID 2507
Gene Name yscH from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2767576
NCBI Protein GI 45478527
Locus Tag YP_pCD26
Protein Accession NP_995354.1
Other Database IDs UniProtKB-ID: YSCH_YERPE
UniRef100: UniRef100_P68590
UniRef90: UniRef90_P68590
UniRef50: UniRef50_P68590
UniParc: UPI000013C092
EMBL: AF074612
EMBL: AF053946
EMBL: AL117189
EMBL: AE017043
EMBL-CDS: AAC69828.1
EMBL-CDS: AAC62547.1
EMBL-CDS: CAB54934.1
EMBL-CDS: AAS58545.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
RefSeq_NT: NC_005813.1
PDB: 1Z21
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.57
KEGG: ypm:YP_pCD26
HOGENOM: HBG273959
OMA: LIPRNGM
Pr
Taxonomy ID 229193
Plasmid No pCD1
Gene Starting Position 18742
Gene Ending Position 19239
Gene Strand (Orientation) -
Protein Name putative type III secretion protein YscH
DNA Sequence 
>gi|45478502:18742-19239 Yersinia pestis biovar Microtus str. 91001 plasmid pCD1, complete sequence
TTTATGTATCCATATCAATTTGATGGCTGTTATGAAGTAGGCTATCTACAATCGAGTTAGACGGTAATAG
GATCATTAATTCTTTATTTATTAACTCTGATAAATAAGGTAATCCAACCTGGCTCTCATTGGGTTTTATA
CCCTCTAATACTTGGAGCAATATTGCTTCCCACCGCTTACCAAACGAGTCAAACTGCTGCAATACACTAC
GCAATTCAGGTAAATCTATAGCCGGTACAACAGACCCTTGATGTTGACCGAAACGCGCCAGTAACGCCTC
ACGTACTGGCGTCGCCAAAACCTCAAGAACGGCATGGTCAGGAGGGTTACTGGCATAATATTGCTGCCAC
AGAACTTCCCGTGTCTTTTCAGCGGATTCACTTTTTAGCTTATTCTCCAGTTGTGTTTTCAGCTCAGATG
CTACCGGTTGTAGCGTAGAGACTGCCTGAGACGAAGACATCAACGATGTAATGGAACCTCTATTAAGGGT
AACCGTCA
Protein Sequence 
>gi|45478527|ref|NP_995354.1| putative type III secretion protein YscH [Yersinia pestis biovar Microtus str. 91001] MTVTLNRGSITSLMSSSQAVSTLQPVASELKTQLENKLKSESAEKTREVLWQQYYASNPPDHAVLEVLATPVREALLARFGQHQGSVVPAIDLPELRSVLQQFDSFGKRWEAILLQVLEGIKPNESQVGLPYLSELINKELMILLPSNSIVDSLLHNSHQIDMDT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The LD50 for the mouse of the yscH mutant was 10-fold higher than that of the parental strain indicating that YopR is involved in pathogenesis (Allaoui et al., 1995).
References
Allaoui et al., 1995: Allaoui A, Schulte R, Cornelis GR. Mutational analysis of the Yersinia enterocolitica virC operon: characterization of yscE, F, G, I, J, K required for Yop secretion and yscH encoding YopR. Molecular microbiology. 1995; 18(2); 343-355. [PubMed: 8709853].