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ypkA from Yersinia pestis biovar Microtus str. 91001

Victor ID 2505
Gene Name ypkA from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2767571
NCBI Protein GI 45478514
Locus Tag YP_pCD13
Protein Accession NP_995341.1
Other Database IDs UniProtKB-ID: YPKA_YERPE
UniRef100: UniRef100_Q9RI12
UniRef90: UniRef90_Q9RI12
UniRef50: UniRef50_Q9RI12
UniParc: UPI00000D1292
EMBL: AF074612
EMBL: AF053946
EMBL: AL117189
EMBL: AE017043
EMBL-CDS: AAC69765.1
EMBL-CDS: AAC62602.1
EMBL-CDS: CAB54949.1
EMBL-CDS: AAS58532.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
RefSeq_NT: NC_005813.1
MINT: MINT-1503406
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.72c
KEGG: ypm:YP_pCD13
HOGENOM: HBG299066
OMA:
Taxonomy ID 229193
Plasmid No pCD1
Gene Starting Position 7203
Gene Ending Position 9401
Gene Strand (Orientation) +
Protein Name putative targeted effector protein kinase YpkA
DNA Sequence 
>gi|45478502:7203-9401 Yersinia pestis biovar Microtus str. 91001 plasmid pCD1, complete sequence
CATGAAAAGCGTGAAAATCATGGGAACTATGCCACCGTCGATCTCCCTCGCCAAAGCTCATGAGCGCATC
AGCCAACATTGGCAAAATCCTGTCGGTGAGCTCAATATCGGAGGAAAACGGTATAGAATTATCGATAATC
AAGTGTTGCGCTTGAACCCCCACAGTGGTTTTTCTCTCTTTCGAGAAGGGGTTGGTAAGATCTTTTCGGG
GAAGATGTTTAACTTTTCAATTGCTCGTAACCTTACTGACACACTCCATGCGGCCCAGAAAACGACTTCG
CAGGAGCTAAGGTCTGATATCCCCAATGCTCTCAGTAATCTCTTTGGAGCCAAGCCACAGACCGAACTGC
CGCTGGGTTGGAAAGGGGAGCCCTTGTCAGGAGCTCCGGATCTTGAAGGGATGCGAGTGGCTGAAACCGA
TAAGTTTGCCGAGGGCGAAAGCCATATTAGTATAATAGAAACTAAGGATAAGCAGCGGTTGGTAGCTAAG
ATTGAACGCTCCATTGCCGAGGGGCATTTGTTCGCAGAACTGGAGGCTTATAAACACATCTATAAAACCG
CGGGCAAACATCCTAATCTTGCCAATGTTCATGGCATGGCTGTGGTGCCATACGGTAACCGTAAGGAGGA
AGCATTGCTGATGGATGAGGTGGATGGTTGGCGTTGTTCTGACACACTAAGAACCCTCGCCGATAGCTGG
AAGCAAGGAAAGATCAATAGTGAAGCCTACTGGGGAACGATCAAGTTTATTGCCCATCGGCTATTAGATG
TAACCAATCACCTTGCCAAGGCAGGGGTAGTACATAACGATATCAAACCCGGTAATGTGGTATTTGACCG
CGCTAGCGGAGAGCCCGTTGTTATTGATCTAGGATTACACTCTCGTTCAGGGGAACAACCTAAGGGGTTT
ACAGAATCCTTCAAAGCGCCGGAGCTTGGAGTAGGAAACCTAGGCGCATCAGAAAAGAGCGATGTTTTTC
TCGTAGTGTCAACCCTTCTACATTGTATCGAAGGTTTTGAGAAAAATCCGGAGATAAAGCCTAATCAAGG
ACTGAGATTCATTACCTCAGAACCAGCGCACGTAATGGATGAGAATGGTTATCCAATCCATCGACCTGGT
ATAGCTGGAGTCGAGACAGCCTATACACGCTTCATCACAGACATCCTTGGCGTTTCCGCTGACTCAAGAC
CTGATTCCAACGAAGCCAGACTCCACGAGTTCTTGAGCGACGGAACTATCGACGAGGAGTCGGCCAAGCA
GATCCTAAAAGATACCCTAACCGGAGAAATGAGCCCATTATCTACTGATGTAAGGCGGATAACACCCAAG
AAGCTTCGGGAGCTATCTGATTTGCTTAGGACGCATTTGAGCAGTGCAGCAACTAAGCAATTGGATATGG
GGGGGGTTTTGTCGGATCTTGATACCATGTTGGTGGCACTCGACAAGGCCGAACGCGAGGGGGGAGTAGA
CAAGGATCAGTTGAAGAGTTTTAACAGTTTGATTCTGAAGACTTACAGAGTGATTGAAGACTATGTCAAA
GGCAGAGAAGGGGATACCAAGAATTCCAGTACGGAAGTATCCCCCTATCATCGCAGTAACTTTATGCTAT
CGATCGTCGAACCTTCACTGCAGAGGATCCAGAAGCATCTGGACCAGACACACTCTTTTTCTGATATCGG
TTCACTAGTGCGCGCACATAAGCACCTGGAAACGCTTTTAGAGGTCTTAGTCACCTTGTCACAGCAAGGG
CAGCCCGTGTCCTCTGAAACCTACGGCTTCCTGAATCGATTAACTGAGGCTAAGATCACCTTGTCGCAGC
AATTGAATACTCTCCAGCAGCAGCAGGAGAGTGCGAAAGCGCAATTATCTATTCTGATTAATCGTTCAGG
TTCTTGGGCCGATGTTGCTCGTCAGTCCCTGCAGCGTTTTGACAGTACCCGGCCTGTAGTGAAATTCGGC
ACTGAGCAGTATACCGCAATTCACCGTCAGATGATGGCGGCCCATGCAGCTATTACGCTACAGGAGGTAT
CGGAGTTTACTGATGATATGCGAAACTTTACAGTGGACTCTATTCCACTACTGATTCAACTTGGACGAAG
CAGTTTAATGGATGAGCATTTGGTTGAACAGAGAGAAAAGTTGCGAGAGCTGACGACCATCGCCGAGCGA
CTGAACCGGTTGGAGCGGGAATGGATGTG
Protein Sequence 
>gi|45478514|ref|NP_995341.1| putative targeted effector protein kinase YpkA [Yersinia pestis biovar Microtus str. 91001] MKSVKIMGTMPPSISLAKAHERISQHWQNPVGELNIGGKRYRIIDNQVLRLNPHSGFSLFREGVGKIFSGKMFNFSIARNLTDTLHAAQKTTSQELRSDIPNALSNLFGAKPQTELPLGWKGEPLSGAPDLEGMRVAETDKFAEGESHISIIETKDKQRLVAKIERSIAEGHLFAELEAYKHIYKTAGKHPNLANVHGMAVVPYGNRKEEALLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMDENGYPIHRPGIAGVETAYTRFITDILGVSADSRPDSNEARLHEFLSDGTIDEESAKQILKDTLTGEMSPLSTDVRRITPKKLRELSDLLRTHLSSAATKQLDMGGVLSDLDTMLVALDKAEREGGVDKDQLKSFNSLILKTYRVIEDYVKGREGDTKNSSTEVSPYHRSNFMLSIVEPSLQRIQKHLDQTHSFSDIGSLVRAHKHLETLLEVLVTLSQQGQPVSSETYGFLNRLTEAKITLSQQLNTLQQQQESAKAQLSILINRSGSWADVARQSLQRFDSTRPVVKFGTEQYTAIHRQMMAAHAAITLQEVSEFTDDMRNFTVDSIPLLIQLGRSSLMDEHLVEQREKLRELTTIAERLNRLEREWM
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ypkA mutants of Y. pseudotuberculosis are attenuated in mice (Galyov et al., 1993).
COG COG0515RTKL, under R: General function prediction only; T: Signal transduction mechanisms; K: Transcription; L: Replication, recombination and repair
References
Galyov et al., 1993: Galyov EE, HÃ¥kansson S, Forsberg A, Wolf-Watz H. A secreted protein kinase of Yersinia pseudotuberculosis is an indispensable virulence determinant. Nature. 1993; 361(6414); 730-732. [PubMed: 8441468].