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yopQ from Yersinia pestis biovar Microtus str. 91001

Victor ID 2503
Gene Name yopQ from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2767553
NCBI Protein GI 45478565
Locus Tag YP_pCD68
Protein Accession NP_995392.1
Other Database IDs UniProtKB-ID: Q74YW7_YERPE
UniRef100: UniRef100_O68704
UniRef90: UniRef90_P27474
UniRef50: UniRef50_P27474
UniParc: UPI0000253F7A
EMBL: AE017043
EMBL-CDS: AAS58583.1
RefSeq_NT: NC_005813.1
GenomeReviews: AE017043_GR
KEGG: ypm:YP_pCD68
HOGENOM: HBG757033
ProtClustDB: CLSK862117
Taxonomy ID 229193
Plasmid No pCD1
Gene Starting Position 48607
Gene Ending Position 49170
Gene Strand (Orientation) +
Protein Name putative virulence determinant protein YopQ
DNA Sequence 
>gi|45478502:48607-49170 Yersinia pestis biovar Microtus str. 91001 plasmid pCD1, complete sequence
TTTGGGAGTAGTAACTATGTTTATTAAAGATACTTATAACATGCGTGCTTTATGTACCGCTCTTGAACAG
TCGGCTCCTGATACAATAATAAATACATCTAAAGAAGAAAATAACAGTTACTACTGCGCTACTGCTCATT
TACTGAGAACGGATGTTTGTTCATTGGTCAATAGAGTAGGGATTGAACCACTTAAAAGTGGATCAATATT
ATCTACTTTAGAAGAGTTATGGCAGGCTGTTGGTATAGTATATCGCTTATACGAATGGCAACATGTCAGC
GATATTGACACCAATTTTAAGAAACTACCCAATAATTCTGATTTTGGTCTTGTGTTTTCTGTATTAGATT
GTGATATAGAGTATGTGTTCATAGGGAAAAAAGACAGTGAAGGGAATATAGAATTTTATGATCCGAAAAA
CTCTCTACTTATAGAGAATGATGACATAAAAAAATATTTATATGATGAAGATTTTCATCGTTTTTGTATT
ATGCTGATCATCTCTAAATCTGAGTTGGAGGAATTGAGTCGCGAATCCTGCGATCAAGAATGTATTATGG
GATG
Protein Sequence 
>gi|45478565|ref|NP_995392.1| putative virulence determinant protein YopQ [Yersinia pestis biovar Microtus str. 91001] MGVVTMFIKDTYNMRALCTALEQSAPDTIINTSKEENNSYYCATAHLLRTDVCSLVNRVGIEPLKSGSILSTLEELWQAVGIVYRLYEWQHVSDIDTNFKKLPNNSDFGLVFSVLDCDIEYVFIGKKDSEGNIEFYDPKNSLLIENDDIKKYLYDEDFHRFCIMLIISKSELEELSRESCDQECIMG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopK (yopQ) mutant has an increased LD50 dose in mice, and infected mice died after 5 days as compared to mice infected with the wild type died after just 3 days (Straley and Bowmer, 1986).
References
Straley and Bowmer, 1986: Straley SC, Bowmer WS. Virulence genes regulated at the transcriptional level by Ca2+ in Yersinia pestis include structural genes for outer membrane proteins. Infection and immunity. 1986; 51(2); 445-454. [PubMed: 3002984].