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virF from Shigella flexneri 5a

Victor ID 25
Gene Name virF from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876428
NCBI Protein GI 13448990
Locus Tag pWR501_p051
Protein Accession NP_085206.1
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 36199
Gene Ending Position 37008
Gene Strand (Orientation) -
Protein Name transcriptional activator of virulence loci
DNA Sequence 
>gi|13448939:36199-37008 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TTTAAAATTTTTTATGATATAAGTAAAATTTCTTTGGAGTTATACCATAATATTCATTAAATTTCCTTAT
AAAATAAGATGGGCTTGATATTCCGATAAGTCTTGATACATCATTAATATAGCTTTGACTATTCAATAAA
AGCTTTGCTGCATGATGCATGCGAATATCAAGAAGGATTTGTTGAAATGTTAATTTTTCACTCTCCAATC
GTTTTCTAACAGCTATTTCTGATAAATTCAAGTTATTTGAAATATCAGAAAGACGCCATCTCTTCTCGAT
GTTTTTTTCAACAATCTTCCTTATCTGATCAGAAAAACTAAGAGAAGAAGCTATCGATATCGAAGTATAT
AAAGCTTCCTCATCAGAAACAGCTGATAAAAGGCAAGCTAAACTATAGATCTTTCTTTTGCCGAAAGGCA
TCTCTTTTATAGATTTGAACAAATCGATAGAAACCTCCTCCTCAGAGAGGAGGAATATTTTTTTGTTTAA
CCCCCTTTTCTCCTCAGAATAGGAGTGTTGAAATGAATAAATTGGTTCCATTATTCTAATAATGCTTAAT
AATAAATTTCTGTCAAGGCTTATAATCTCAAATGGATTAATGCTATCAGATTTTTTTATGGAGACGTTTA
TTTGTATATTTCGCTCTATAAAAGCAATTTGCCCTTCATCGATAGTCAAAGTTTCATTGCCTGAGCTAAC
CGTCATTGAACACCTTTTTGCATATAAAATAATATAGTTATGCAAGCGAACCTTTATATCTATTTTGTTT
TTATGTCCCATATCCATCATAAATTCAACAGAATATACCA
Protein Sequence 
>gi|13448990|ref|NP_085206.1| transcriptional activator of virulence loci [Shigella flexneri 5a str. M90T] MVYSVEFMMDMGHKNKIDIKVRLHNYIILYAKRCSMTVSSGNETLTIDEGQIAFIERNIQINVSIKKSDSINPFEIISLDRNLLLSIIRIMEPIYSFQHSYSEEKRGLNKKIFLLSEEEVSIDLFKSIKEMPFGKRKIYSLACLLSAVSDEEALYTSISIASSLSFSDQIRKIVEKNIEKRWRLSDISNNLNLSEIAVRKRLESEKLTFQQILLDIRMHHAAKLLLNSQSYINDVSRLIGISSPSYFIRKFNEYYGITPKKFYLYHKKF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virF knockouts are non-invasive to host cells (Hurt et al., 2010).
References
Hurt et al., 2010: Hurt JK, McQuade TJ, Emanuele A, Larsen MJ, Garcia GA. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 2010; 15(4); 379-387. [PubMed: 20237205].