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yopD from Yersinia pestis biovar Microtus str. 91001

Victor ID 2499
Gene Name yopD from Yersinia pestis biovar Microtus str. 91001
Sequence Strain (Species/Organism) Yersinia pestis biovar Microtus str. 91001
NCBI Gene ID 2767507
NCBI Protein GI 45478556
Locus Tag YP_pCD55
Protein Accession NP_995383.1
Other Database IDs UniProtKB-ID: Q7ARJ1_YERPE
UniRef100: UniRef100_Q06131
UniRef90: UniRef90_Q06131
UniRef50: UniRef50_Q06131
UniParc: UPI00000D606B
EMBL: AE017043
EMBL: AL117189
EMBL-CDS: AAS58574.1
EMBL-CDS: CAB54905.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_005813.1
HSSP: Q06131
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.28c
KEGG: ypm:YP_pCD55
HOGENOM: HBG299047
OMA: MAVVSGV
ProtClustDB: CLSK862121
BioCyc: YPES214092:YPCD1.28C-MONOMER
Taxonomy ID 229193
Plasmid No pCD1
Gene Starting Position 40644
Gene Ending Position 41564
Gene Strand (Orientation) +
Protein Name putative Yop negative regulation/targeting component YopD
DNA Sequence 
>gi|45478502:40644-41564 Yersinia pestis biovar Microtus str. 91001 plasmid pCD1, complete sequence
CATGACAATAAATATCAAGACAGACAGCCCAATTATCACGACCGGTTCACAGCTTGATGCCATCACTACA
GAGACAGTCAAGCAAAGCGGTGAGATTAAAAAAACAGAAGACACCCGTCATGAAGCACAAGCAATAAAGA
GTAGCGAGGCAAGCTTATCTCGGTCACAGGTGCCAGAATTGATCAAACCGAGCCAGGGAATCAATGTTGC
ATTACTGAGTAAAAGCCAGGGTGATCTTAATGGTACTTTAAGTATCTTGTTGTTGCTGTTGGAACTGGCA
CGTAAAGCGCGAGAAATGGGTTTGCAACAAAGGGATATAGAAAATAAAGCTACTATTACTGCCCAAAAGG
AGCAGGTAGCGGAGATGGTCAGCGGTGCAAAACTGATGATCGCCATGGCGGTGGTGTCTGGCATCATGGC
TGCTACTTCTACGGTTGCTAGTGCTTTTTCTATAGCGAAAGAGGTGAAAATAGTTAAACAGGAACAAATT
CTAAACAGTAATATTGCTGGCCGCGAACAACTTATTGATACAAAAATGCAGCAAATGAGTAACATTGGTG
ATAAAGCGGTAAGCAGAGAGGATATCGGGAGAATATGGAAACCAGAGCAGGTAGCGGATCAAAATAAGCT
GGCATTATTGGATAAAGAATTCAGAATGACCGACTCAAAAGCCAATGCGTTTAATGCCGCAACGCAGCCG
TTAGGACAAATGGCAAACAGTGCGATTCAAGTTCATCAAGGGTATTCTCAAGCCGAGGTCAAAGAGAAAG
AAGTCAATGCAAGTATTGCTGCCAACGAGAAGCAAAAAGCCGAAGAGGCGATGAACTATAATGATAACTT
TATGAAAGATGTCCTGCGCTTGATTGAACAATATGTTAGCAGTCATACTCACGCCATGAAAGCCGCTTTT
GGTGTTGTCTG
Protein Sequence 
>gi|45478556|ref|NP_995383.1| putative Yop negative regulation/targeting component YopD [Yersinia pestis biovar Microtus str. 91001] MTINIKTDSPIITTGSQLDAITTETVKQSGEIKKTEDTRHEAQAIKSSEASLSRSQVPELIKPSQGINVALLSKSQGDLNGTLSILLLLLELARKAREMGLQQRDIENKATITAQKEQVAEMVSGAKLMIAMAVVSGIMAATSTVASAFSIAKEVKIVKQEQILNSNIAGREQLIDTKMQQMSNIGDKAVSREDIGRIWKPEQVADQNKLALLDKEFRMTDSKANAFNAATQPLGQMANSAIQVHQGYSQAEVKEKEVNASIAANEKQKAEEAMNYNDNFMKDVLRLIEQYVSSHTHAMKAAFGVV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopD mutants are unable to induce cytotoxicity in HeLa cells (Rosqvist et al., 1991).
References
Rosqvist et al., 1991: Rosqvist R, Forsberg A, Wolf-Watz H. Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption. Infection and immunity. 1991; 59(12); 4562-4569. [PubMed: 1937815].