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lcrV from Yersinia pestis CA88-4125

Victor ID 2485
Gene Name lcrV from Yersinia pestis CA88-4125
Sequence Strain (Species/Organism) Yersinia pestis CA88-4125
NCBI Gene ID 5236071
NCBI Protein GI 149192708
Locus Tag YPE_4223
Protein Accession YP_001293940.1
Other Database IDs UniProtKB-ID: A6M3U1_YERPE
UniRef100: UniRef100_P0C7U7
UniRef90: UniRef90_A9R9H4
UniRef50: UniRef50_A9R9H4
UniParc: UPI000012E2BB
EMBL: CP000722
EMBL-CDS: ABR14856.1
RefSeq_NT: NC_009595.1
OMA: MAGLENS
ProtClustDB: CLSK862124
Taxonomy ID 412420
Plasmid No pCD1
Gene Starting Position 54038
Gene Ending Position 55018
Gene Strand (Orientation) +
Protein Name V antigen
DNA Sequence 
>gi|149192647:54038-55018 Yersinia pestis CA88-4125 plasmid pCD1, complete sequence
TATGATTAGAGCCTACGAACAAAACCCACAACATTTTATTGAGGATCTAGAAAAAGTTAGGGTGGAACAA
CTTACTGGTCATGGTTCTTCAGTTTTAGAAGAATTGGTTCAGTTAGTCAAAGATAAAAATATAGATATTT
CCATTAAATATGATCCCAGAAAAGATTCGGAGGTTTTTGCCAATAGAGTAATTACTGATGATATCGAATT
GCTCAAGAAAATCCTAGCTTATTTTCTACCCGAGGATGCCATTCTTAAAGGCGGTCATTATGACAACCAA
CTGCAAAATGGCATCAAGCGAGTAAAAGAGTTCCTTGAATCATCGCCGAATACACAATGGGAATTGCGGG
CGTTCATGGCAGTAATGCATTTCTCTTTAACCGCCGATCGTATCGATGATGATATTTTGAAAGTGATTGT
TGATTCAATGAATCATCATGGTGATGCCCGTAGCAAGTTGCGTGAAGAATTAGCTGAGCTTACCGCCGAA
TTAAAGATTTATTCAGTTATTCAAGCCGAAATTAATAAGCATCTGTCTAGTAGTGGCACCATAAATATCC
ATGATAAATCCATTAATCTCATGGATAAAAATTTATATGGTTATACAGATGAAGAGATTTTTAAAGCCAG
CGCAGAGTACAAAATTCTCGAGAAAATGCCTCAAACCACCATTCAGGTGGATGGGAGCGAGAAAAAAATA
GTCTCGATAAAGGACTTTCTTGGAAGTGAGAATAAAAGAACCGGGGCGTTGGGTAATCTGAAAAACTCAT
ACTCTTATAATAAAGATAATAATGAATTATCTCACTTTGCCACCACCTGCTCGGATAAGTCCAGGCCGCT
CAACGACTTGGTTAGCCAAAAAACAACTCAGCTGTCTGATATTACATCACGTTTTAATTCAGCTATTGAA
GCACTGAACCGTTTCATTCAGAAATATGATTCAGTGATGCAACGTCTGCTAGATGACACGTCTGGTAAAT
G
Protein Sequence 
>gi|149192708|ref|YP_001293940.1| V antigen [Yersinia pestis CA88-4125] MIRAYEQNPQHFIEDLEKVRVEQLTGHGSSVLEELVQLVKDKNIDISIKYDPRKDSEVFANRVITDDIELLKKILAYFLPEDAILKGGHYDNQLQNGIKRVKEFLESSPNTQWELRAFMAVMHFSLTADRIDDDILKVIVDSMNHHGDARSKLREELAELTAELKIYSVIQAEINKHLSSSGTINIHDKSINLMDKNLYGYTDEEIFKASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSENKRTGALGNLKNSYSYNKDNNELSHFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEALNRFIQKYDSVMQRLLDDTSGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lcrV mutants are avirulent in mice (Skrzypek and Straley, 1995).
References
Skrzypek and Straley, 1995: Skrzypek E, Straley SC. Differential effects of deletions in lcrV on secretion of V antigen, regulation of the low-Ca2+ response, and virulence of Yersinia pestis. Journal of bacteriology. 1995; 177(9); 2530-2542. [PubMed: 7730287].