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yopM from Yersinia pestis CA88-4125

Victor ID 2481
Gene Name yopM from Yersinia pestis CA88-4125
Sequence Strain (Species/Organism) Yersinia pestis CA88-4125
NCBI Gene ID 5236067
NCBI Protein GI 149192712
Locus Tag YPE_4227
Protein Accession YP_001293944.1
Other Database IDs UniProtKB-ID: A6M3U5_YERPE
UniRef100: UniRef100_P17778
UniRef90: UniRef90_P17778
UniRef50: UniRef50_P17778
UniParc: UPI000013BCB1
EMBL: CP000722
EMBL-CDS: ABR14860.1
RefSeq_NT: NC_009595.1
OMA: VRENDLT
ProtClustDB: CLSK862120
Taxonomy ID 412420
Plasmid No pCD1
Gene Starting Position 59388
Gene Ending Position 60617
Gene Strand (Orientation) +
Protein Name leucine-rich 15-repeat translocated effector protein
DNA Sequence 
>gi|149192647:59388-60617 Yersinia pestis CA88-4125 plasmid pCD1, complete sequence
TATGTTCATAAATCCAAGAAATGTATCTAATACTTTTTTGCAAGAACCATTACGTCATTCTTCTAATTTA
ACTGAGATGCCGGTTGAGGCAGAAAATGTTAAATCTAAGACTGAATATTATAATGCATGGTCGGAATGGG
AACGAAATGCCCCTCCGGGGAATGGTGAACAGAGGGAAATGGCGGTTTCAAGGTTACGAGATTGCCTGGA
CCGACAAGCCCATGAGCTAGAACTAAATAATCTGGGGCTGAGTTCTTTGCCGGAATTACCTCCGCATTTA
GAGAGTTTAGTGGCGTCATGTAATTCTCTTACAGAATTACCGGAATTACCGCAGAGCCTGAAATCACTTC
TAGTTGATAATAACAATCTGAAGGCATTATCCGATTTACCACCTTTACTGGAATATTTAGGTGTCTCTAA
TAATCAGCTGGAAAAATTGCCAGAGTTGCAAAACTCGTCCTTCTTGAAAATTATTGATGTTGATAACAAT
TCACTGAAAAAACTACCTGATTTACCTCCTTCACTGGAGTTTATTGCTGCTGGTAATAATCAGCTGGAAG
AATTGCCAGAGTTGCAAAACTTGCCCTTCTTGACTGCGATTTATGCTGATAACAATTCACTGAAAAAACT
ACCTGATTTACCTCTTTCACTGGAATCTATTGTTGCTGGTAATAATATTCTGGAAGAATTGCCAGAGTTG
CAAAACTTGCCCTTCTTGACTACGATTTATGCTGATAACAATTTACTGAAAACATTACCCGATTTACCCC
CTTCCCTGGAAGCACTTAATGTCAGAGATAATTATTTAACTGATCTGCCAGAATTACCGCAGAGTTTAAC
CTTCTTAGATGTTTCTGAAAATATTTTTTCTGGATTATCGGAATTGCCACCAAACTTGTATTATCTCAAT
GCATCCAGCAATGAAATAAGATCCTTATGCGATTTACCCCCTTCACTGGAAGAACTTAATGTCAGTAATA
ATAAGTTGATCGAACTGCCAGCGTTACCTCCACGCTTAGAACGTTTAATCGCTTCATTTAATCATCTTGC
TGAAGTACCTGAATTGCCGCAAAACCTGAAACAGCTCCACGTAGAGTACAACCCTCTGAGAGAGTTTCCC
GATATACCTGAGTCAGTGGAAGATCTTCGGATGAACTCTGAACGTGTAGTTGATCCATATGAATTTGCTC
ATGAGACTACAGACAAACTTGAAGATGATGTATTTGAGTA
Protein Sequence 
>gi|149192712|ref|YP_001293944.1| leucine-rich repeat-containing translocated effector protein [Yersinia pestis CA88-4125] MFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDIPESVEDLRMNSERVVDPYEFAHETTDKLEDDVFE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopM mutant is attenuated in mice compared to the wild type (Leung et al., 1990).
References
Leung et al., 1990: Leung KY, Reisner BS, Straley SC. YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice. Infection and immunity. 1990; 58(10); 3262-3271. [PubMed: 2401564].