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yopK from Yersinia pestis CA88-4125

Victor ID 2479
Gene Name yopK from Yersinia pestis CA88-4125
Sequence Strain (Species/Organism) Yersinia pestis CA88-4125
NCBI Gene ID 5236061
NCBI Protein GI 149192717
Locus Tag YPE_4233
Protein Accession YP_001293949.1
Other Database IDs UniProtKB-ID: A6M3V0_YERPE
UniRef100: UniRef100_O68704
UniRef90: UniRef90_P27474
UniRef50: UniRef50_P27474
UniParc: UPI00000D6079
EMBL: CP000722
EMBL-CDS: ABR14865.1
RefSeq_NT: NC_009595.1
OMA: KGNIELY
ProtClustDB: CLSK862117
Taxonomy ID 412420
Plasmid No pCD1
Gene Starting Position 64843
Gene Ending Position 65391
Gene Strand (Orientation) +
Protein Name secreted targeting protein, possible regulator, Type III system
DNA Sequence 
>gi|149192647:64843-65391 Yersinia pestis CA88-4125 plasmid pCD1, complete sequence
TATGTTTATTAAAGATACTTATAACATGCGTGCTTTATGTACCGCTCTTGAACAGTCGGCTCCTGATACA
ATAATAAATACATCTAAAGAAGAAAATAACAGTTACTACTGCGCTACTGCTCATTTACTGAGAACGGATG
TTTGTTCATTGGTCAATAGAGTAGGGATTGAACCACTTAAAAGTGGATCAATATTATCTACTTTAGAAGA
GTTATGGCAGGCTGTTGGTATAGTATATCGCTTATACGAATGGCAACATGTCAGCGATATTGACACCAAT
TTTAAGAAACTACCCAATAATTCTGATTTTGGTCTTGTGTTTTCTGTATTAGATTGTGATATAGAGTATG
TGTTCATAGGGAAAAAAGACAGTGAAGGGAATATAGAATTTTATGATCCGAAAAACTCTCTACTTATAGA
GAATGATGACATAAAAAAATATTTATATGATGAAGATTTTCATCGTTTTTGTATTATGCTGATCATCTCT
AAATCTGAGTTGGAGGAATTGAGTCGCGAATCCTGCGATCAAGAATGTATTATGGGATG
Protein Sequence 
>gi|149192717|ref|YP_001293949.1| secreted targeting protein, regulator, Type III system [Yersinia pestis CA88-4125] MFIKDTYNMRALCTALEQSAPDTIINTSKEENNSYYCATAHLLRTDVCSLVNRVGIEPLKSGSILSTLEELWQAVGIVYRLYEWQHVSDIDTNFKKLPNNSDFGLVFSVLDCDIEYVFIGKKDSEGNIEFYDPKNSLLIENDDIKKYLYDEDFHRFCIMLIISKSELEELSRESCDQECIMG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopK mutant has an increased LD50 dose in mice, and infected mice died after 5 days as compared to mice infected with the wild type died after just 3 days (Straley and Bowmer, 1986).
References
Straley and Bowmer, 1986: Straley SC, Bowmer WS. Virulence genes regulated at the transcriptional level by Ca2+ in Yersinia pestis include structural genes for outer membrane proteins. Infection and immunity. 1986; 51(2); 445-454. [PubMed: 3002984].