Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

pks15 from Mycobacterium tuberculosis H37Rv

Victor ID 247
Gene Name pks15 from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887291
NCBI Protein GI 15610084
Locus Tag Rv2947c
Protein Accession NP_217463.1
Other Database IDs UniProtKB-ID: P96284_MYCTU
UniRef100: UniRef100_A5U6V5
UniRef90: UniRef90_A5WRJ9
UniRef50: UniRef50_A8L4B2
UniParc: UPI00000D502D
EMBL: BX842581
EMBL-CDS: CAB06102.1
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000001346.
EnsemblGenome_TRS: EBMYCT00000001346
EnsemblGenome_PRO: EBMYCP00000001346
GenomeReviews: AL123456_GR
KEGG: mtu:Rv2947c
TubercuList: Rv2947c
HOGENOM: HBG669988
OMA: ANDLDEY
ProtClustDB: CLSK792183
Taxonomy ID 83332
Gene Starting Position 3296349
Gene Ending Position 3297839
Gene Strand (Orientation) -
Protein Name PROBABLE POLYKETIDE SYNTHASE PKS15
DNA Sequence 
>gi|57116681:3296349-3297839 Mycobacterium tuberculosis H37Rv, complete genome
ATCACCCACGGCACCATCGACGGCCGCGGCCCCCGGTGCTTTCGCTCGCCTCAACCGGCGCCTCTGCGGG
GGCTGGTACGGGGGCCTCTTCCAAGATCAGATGCGCGTTGGTGCCGCTGATCCCAAAGGAGGACACCGCC
GCCCGGCGCGGACGCCCGTCAACCGACCACTCCCTGGCCTCGGTCAACACCGACACCGCGCCGCTGGTCC
AATCCACCCGCGGGGAAGGCTCATCCACATGCAACGTCGCCGGCATCACCCCATGACGCATCGCCTGCAC
CATCTTGATCACCCCGGCGACCCCCGCGGCGGCCTGGGTGTGGCCCATGTTCGACTTGATTGAGCCCACC
CACAGCGGCTGCTCCGCTGGACCTCCCTGCCCGTAGGTGGACAGCAATGCCTGCGCTTCGATGGGATCAC
CCAACGTGGTGGCGGTCCCGTGTGCCTCCACCACGTCTACGTCTGCGGCGGACAACCCGGCGTTGGCCAA
CGCCACCTGGATCACTCGCTGCTGGGCGAGCCCATTGGGCGCGGTCAGCCCATTGGACGCACCATCCTGG
TTGACCGCGCTCCCCCGCACCACCGCCAGCACCGAATGCCCCAACCGCCGGGCGTCCGATAGCCGCTCCA
GCACAACCACCCCGGCGCCCTCGCCCCACCCGGTGCCGTCGGCCGCGGCCGCAAACGCCTTACATCGCCC
ATCGGCAGCCAACCCCCGCTGCCGGGAAAACCCCACAAAAATCGACGGCAGCCCCATCACCGTCACCCCA
CCGGCCAACGCCAAATCACACTCCCCGGAGCGCAATGACGACATCGCCCAATGGATCGCCACCAACGACG
ACGAACAAGCGGTATCCACTGACACCGCCGGGCCCTGCAGCCCCAATACGTACGACACACGTCCCGAGGC
CACGCTGATTGACGTGCCGGTCAACCCGTACCCTTGCAGCCCCCCGGTATCCCTATTGCCGTAACTCGCC
GCGAAAATGCCGGTGTACACCCCGGTCGCCGAACCACGCAACGACAACGGGTCAATCCCCGCGTGCTCCA
ACGCCTCCCACGAAACCTCCAGCATCAACCGCTGCTGAGGATCCATCGCCAACACTTCACTAGGAGCGAT
GCCGAAGAACCCGGCGTCAAAGCCGGTGGCGTCGTCTAGAAATGCCCCCCATCGCGTGTAGGTTTTGCCC
TCAGCGTCGGGATCCGGATCGTATAGCCCCTCAACATCCCAGCCCCGATCGGTCGGAAACTCCGACACCA
CGTCGCGCCCCGCCGAAACGACATCCCAGAGTCCGTCCGGGCCATCCACGCCGCCCGGAAATCGGCAGCC
GATTCCCACCACCGCCACCGGTTCTGTCGCGCGTTGCTCATATTCACGCAGCCGAGCGCGTGTCTCATCG
AGCTCGACAGCAACCTTCTTTAGGTAGTGAAAAAGCTTTTCGCTCTGCTGGTCGGCACCTTCAACGCTCA
TCGTCCGTTGCTCCTCTATCA
Protein Sequence 
>gi|15610084|ref|NP_217463.1| polyketide synthase [Mycobacterium tuberculosis H37Rv] MIEEQRTMSVEGADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVAVVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVYTGIFAASYGNRDTGGLQGYGLTGTSISVASGRVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQVALANAGLSAADVDVVEAHGTATTLGDPIEAQALLSTYGQGGPAEQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSVDGRPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGRGRRWCRG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pks15 mutant is attenuated in mice (Sirakova et al., 2003).
COG COG3321Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Sirakova et al., 2003: Sirakova TD, Dubey VS, Cynamon MH, Kolattukudy PE. Attenuation of Mycobacterium tuberculosis by disruption of a mas-like gene or a chalcone synthase-like gene, which causes deficiency in dimycocerosyl phthiocerol synthesis. Journal of bacteriology. 2003; 185(10); 2999-3008. [PubMed: 12730158].