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gcvT

Victor ID 239
Gene Name gcvT
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887233
NCBI Protein GI 15609348
Locus Tag Rv2211c
Protein Accession NP_216727.1
Other Database IDs UniProtKB-ID: GCST_MYCTU
UniRef100: UniRef100_P64221
UniRef90: UniRef90_P64221
UniRef50: UniRef50_A0QEZ6
UniParc: UPI000012B362
EMBL: BX842579
EMBL: AE000516
EMBL-CDS: CAA94254.1
EMBL-CDS: AAK46553.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000003462
EnsemblGenome_TRS: EBMYCT00000003464
EnsemblGenome_PRO: EBMYCP00000003464
EnsemblGenome: EBMYCG00000070607
EnsemblGenome_TRS: EBMYCT00000070612
EnsemblGenome_PRO: EBMYCP00000068671
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 2476041
Gene Ending Position 2477180
Gene Strand (Orientation) -
Protein Name glycine cleavage system aminomethyltransferase T
DNA Sequence 
>gi|57116681:2476041-2477180 Mycobacterium tuberculosis H37Rv, complete genome
CTCAGCGCGTTTTCACGGCAACGAACGGCGGACACACCACTTGACATTCGACAGCACGGCCGCGGACGTC
GACATTGATTTGCTGGCCGTCTTCGATGCCGGCATCACTGTCGATCAGCGCCAGCCCGATGCCGACCTGC
AACGTGGGAGAAAACGTTCCCGACGTGGTGACCCCAACCGTCTCATCCCCGACAAGCACAGCCAGCCCGG
GGCGCAGCACACCGCGACCGACCATGCGCAGCCCCCGCAGCAGCCGCCGCGGCCCGGCCGCTTTCTCGGC
CAACAACGCCGCACGACCAAAGAAGGCGTCCTTCCGCCAGCCGACCGCCCAGCCGCATCGGGCCTGCAGC
GGCGAGATGTCCAGCGAAAGCTCGTGCCCGTGCAGCGGATAGCCCATTTCAGTGCGCAGTGTGTCGCGAG
CACCGAGGCCGGCGGGCTCGCCGCCCGCGGCTGATACCGCCGCCAACAGTGCGTCGAACACCACACCCGC
CGACTCCCATGGCGGCAGCAGTTCGTAACCGTGCTCACCGGTGTAGCCGGTGCGACAGACACGCACCGGC
ACCCCCGAGTACGAAGCGTCGGCGTAGCCCATGTAGTCCATCTCGGTTGGCAGCCCCAACGCGGTGAGCA
CGTCGGTCGAACACGGCCCCTGTACGGCCAGCACCGCGTAGGACCGATGCAGATTGGTGATGCTCAGACC
GCCCGGTGCGGCAGCTTGTAGCGCGCCGACCACCGCGGCGGTATTGGCGGCGTTGGGCACCAGAAAGATC
TCGTCGTCGCTGACGTAGTAGGCGATCAGGTCGTCGATCACACCGCCGGATTCGGTGCAGCACAAGGTGT
ATTGCGCCTTGCCGGGCCCGATACGACCCAGGTCGTTGGTGAGCGCGGAGTTGACGAACTGCGCCGCACC
CGGTCCACGGACCAGTGCCTTGCCCAGGTGGCTGACGTCGAAAAGGCCGACGGCGGTGCGGGTGGCGTTG
TGCTCGCTGACGGTTCCGGCATACGAGACCGGCATCAGCCAGCCGCCGAACTCGGCGAAACTCGCACCCA
GCTCGCGATGGCGGTCTTCCAGCGGTCCGTGTATCAGCTCTGGCACATCGCTCACGGCGTCCCACCCTAA
TGGGCGTCCCTGCTGGCACA
Protein Sequence 
>gi|15609348|ref|NP_216727.1| aminomethyltransferase [Mycobacterium tuberculosis H37Rv] MCQQGRPLGWDAVSDVPELIHGPLEDRHRELGASFAEFGGWLMPVSYAGTVSEHNATRTAVGLFDVSHLGKALVRGPGAAQFVNSALTNDLGRIGPGKAQYTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTAAVVGALQAAAPGGLSITNLHRSYAVLAVQGPCSTDVLTALGLPTEMDYMGYADASYSGVPVRVCRTGYTGEHGYELLPPWESAGVVFDALLAAVSAAGGEPAGLGARDTLRTEMGYPLHGHELSLDISPLQARCGWAVGWRKDAFFGRAALLAEKAAGPRRLLRGLRMVGRGVLRPGLAVLVGDETVGVTTSGTFSPTLQVGIGLALIDSDAGIEDGQQINVDVRGRAVECQVVCPPFVAVKTR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0404E, under E: Amino acid transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].