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ftsY

Victor ID 238
Gene Name ftsY
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887205
NCBI Protein GI 15610058
Locus Tag Rv2921c
Protein Accession NP_217437.1
Other Database IDs UniProtKB-ID: FTSY_MYCTU
UniRef100: UniRef100_P66843
UniRef90: UniRef90_P66843
UniRef50: UniRef50_P66843
UniParc: UPI000012AD0D
EMBL: BX842581
EMBL: AE000516
EMBL-CDS: CAA98981.1
EMBL-CDS: AAK47316.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 3.A.5.2.2
EnsemblGenome: EBMYCG00000000121
EnsemblGenome_TRS: EBMYCT00000000121
EnsemblGenome_PRO: EBMYCP00000000121
EnsemblGenome: EBMYCG00000072189
EnsemblGenome_TRS: EBMYCT00000072194
EnsemblGenome_PRO: EBMYCP00000070253
GenomeReviews: AE000516_
Taxonomy ID 83332
Gene Starting Position 3232870
Gene Ending Position 3234138
Gene Strand (Orientation) -
Protein Name PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL RECOGNITION PARTICLE RECEPTOR)
DNA Sequence 
>gi|57116681:3232870-3234138 Mycobacterium tuberculosis H37Rv, complete genome
GCTAGCCGAGCAGGGCGTCGACGAATGCGGCGGGTTCGAAAGGCGCCAGGTCATCGGGGCCTTCACCAAG
CCCGACCAGCTTCACCGGCACCCCAAGTTCCTGTTGAACGCGGAACACAATGCCGCCCTTGGCCGTTCCG
TCCAGTTTGGTGAGCACCGCGCCGCTGATGTCGACGACCTCGGCGAACACTCTGGCCTGCGCCAACCCGT
TCTGTCCGATCGTGGCATCGAGCACCAGCAACACCTCGTCAACGGACGCTCGCCGAGTCACCACGCGCTT
GACCTTGTCCAGCTCGTCCATCAGGCCAACCTTGGTGTGCAGCCGCCCGGCTGTATCGATGAGCACGACG
TCTGCGCCGGCGGCGATGCCCTTGTCGACGGCGTCGAACGCCACCGATGCCGGGTCGGCGCCTTCGGGCC
CGCGAACCACCGCTGCGCCAACCCGCGCCGCCCAGGTCTGTAGCTGATCGGCGGCGGCCGCACGGAAGGT
GTCAGCCGCACCGAGTACGACCCGTCGGCCGTCGGCCACTAGTACCCGCGCCAACTTGCCGACCGTGGTG
GTTTTTCCGGTGCCGTTGACGCCGACGACCAGCAACACCGAAGGATGGCCGGCGTGCGGTAGCGCGCGGA
TCGAGCGGTCCATGCCAGGTTGCAGTTCGTTGATCAGGACGTCACGCAATACCGCCCGGGCGTCGGCCTC
GGTACGCACGTTGCCGCTGGCCAGGCGGCTGCGCAGCTGCGACACCACCGACGCGGTGGCCGCCGGTCCC
AGGTCGGCGACCAGCAGGGTGTCCTCGACGTCTTGCCAGGAGTCCTCGTCCAGGTCGCCGCCGCCGATCA
GTCCCAACAGGCCGCGCCCGAGGGCATTCTGCGATCTGGCGAGCCGTCCGCGCAGTCGTTCCAATCGACC
TTCGGGCGGCGCGATGGCGTCAGCCTCGGGGACCTCTGGAGCCTGGGGTTCTGGCTCAAACTCGGGAAGG
TGTACGTCGGCGATCGTGCGCTTGGGCGCGTCGCGAGGGACGGTCGCATCGTCGCCCACGGCGGGCAGTC
CGCTCGTATCGATCCGCTCGGCCGGCTGGGTCGTCGGCGTCTGACTAAACGTGATGCCAGACGATGCGGT
GTAACCGCCTGAGCGGTCGACAACGCCGCGCTCGGGCCGAGGCGACAGACTGATGCGCCGCCGACGGTAG
AGCACCAGCCCCAGGGTCAGCGCAGCGATGACGACCAGGGCGGCGATGACCGCCGTGGCGATCCACAAAC
CTTCCCACA
Protein Sequence 
>gi|15610058|ref|NP_217437.1| signal recognition particle receptor FtsY [Mycobacterium tuberculosis H37Rv] MWEGLWIATAVIAALVVIAALTLGLVLYRRRRISLSPRPERGVVDRSGGYTASSGITFSQTPTTQPAERIDTSGLPAVGDDATVPRDAPKRTIADVHLPEFEPEPQAPEVPEADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDVEDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQPGMDRSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWAARVGAAVVRGPEGADPASVAFDAVDKGIAAGADVVLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATIGQNGLAQARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDLAPFEPAAFVDALLG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0552U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].