Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

eltA from Escherichia coli E24377A

Victor ID 2300
Gene Name eltA from Escherichia coli E24377A
Sequence Strain (Species/Organism) Escherichia coli E24377A
NCBI Gene ID 5585630
NCBI Protein GI 157149353
Locus Tag EcE24377A_F0020
Protein Accession YP_001451390.1
Other Database IDs UniProtKB-ID: A7ZGL8_ECO24
UniRef100: UniRef100_A7ZGL8
UniRef90: UniRef90_P43530
UniRef50: UniRef50_P43528
UniParc: UPI00015C4A27
EMBL: CP000795
EMBL-CDS: ABV16233.1
RefSeq_NT: NC_009786.1
EnsemblGenome: EBESCG00000022848.
EnsemblGenome_TRS: EBESCT00000023794
EnsemblGenome_PRO: EBESCP00000022688
GenomeReviews: CP000795_GR
KEGG: ecw:EcE24377A_F0020
eggNOG: NOG137155
HOGENOM: HBG467666
OMA: NITFIFF
ProtClustDB: CLSK874386
BioCyc: ECOL331111:ECE24377A_F0020-MONOMER
Taxonomy ID 331111
Plasmid No pETEC_80
Gene Starting Position 16615
Gene Ending Position 17424
Gene Strand (Orientation) +
Protein Name heat-labile enterotoxin A
DNA Sequence 
>gi|157149330:16615-17424 Escherichia coli E24377A plasmid pETEC_80, complete sequence
ATTGTCTTCTTGTATGATATATAAGTTTTCCTCGATGAAAAATATAACTTTCATTTTTTTTATTTTATTA
GCATCGCCATTATATGCAAATGGCGACAAATTATACCGTGCTGACTCTAGACCCCCAGATGAAATAAAAC
GTTCCGGAGGTCTTATGCCCAGAGGGCATAATGAGTACTTCGATAGAGGAACTCAAATGAATATTAATCT
TTATGATCACGCGAGAGGAACACAAACCGGCTTTGTCAGATATGATGACGGATATGTTTCCACTTCTCTT
AGTTTGAGAAGTGCTCACTTAGCAGGACAGTCTATATTATCAGGATATTCCACTTACTATATATATGTTA
TAGCGACAGCACCAAATATGTTTAATGTTAATGATGTATTAGGCGTATACAGCCCTCACCCATATGAACA
GGAGGTTTCTGCGTTAGGTGGAATACCATATTCTCAGATATATGGATGGTATCGTGTTAATTTTGGTGTG
ATTGATGAACGATTACATCGTAACAGGGAATATAGAGACCGGTATTACAGAAATCTGAATATAGCTCCGG
CAGAGGATGGTTACAGATTAGCAGGTTTCCCACCGGATCACCAAGCTTGGAGAGAAGAACCCTGGATTCA
TCATGCACCACAAGGTTGTGGAAATTCATCAAGAACAATTACAGGTGATACTTGTAATGAGGAGACCCAG
AATCTGAGCACAATATATCTCAGGAAATATCAATCAAAAGTTAAGAGGCAGATATTTTCAGACTATCAGT
CAGAGGTTGACATATATAACAGAATTCGGGATGAATTATG
Protein Sequence 
>gi|157149353|ref|YP_001451390.1| heat-labile enterotoxin A [Escherichia coli E24377A] MSSCMIYKFSSMKNITFIFFILLASPLYANGDKLYRADSRPPDEIKRSGGLMPRGHNEYFDRGTQMNINLYDHARGTQTGFVRYDDGYVSTSLSLRSAHLAGQSILSGYSTYYIYVIATAPNMFNVNDVLGVYSPHPYEQEVSALGGIPYSQIYGWYRVNFGVIDERLHRNREYRDRYYRNLNIAPAEDGYRLAGFPPDHQAWREEPWIHHAPQGCGNSSRTITGDTCNEETQNLSTIYLRKYQSKVKRQIFSDYQSEVDIYNRIRDEL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Deletion mutants of eltA and eltB had decreased levels of inducing cAMP secretion in an in vitro culture system, and had less adherence to IPEC-J2 and Caco-2 cells than the wild-type ETEC (Johnson et al., 2009).
References
Johnson et al., 2009: Johnson AM, Kaushik RS, Francis DH, Fleckenstein JM, Hardwidge PR. Heat-labile enterotoxin promotes Escherichia coli adherence to intestinal epithelial cells. Journal of bacteriology. 2009; 191(1); 178-186. [PubMed: 18978047].