Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

eatA from Escherichia coli E24377A

Victor ID 2289
Gene Name eatA from Escherichia coli E24377A
Sequence Strain (Species/Organism) Escherichia coli E24377A
NCBI Gene ID 5585855
NCBI Protein GI 157149562
Locus Tag EcE24377A_E0051
Protein Accession YP_001451588.1
Other Database IDs UniProtKB-ID: A7ZH66_ECO24
UniRef100: UniRef100_A7ZH66
UniRef90: UniRef90_Q84GK0
UniRef50: UniRef50_Q84GK0
UniParc: UPI00015C4B16
EMBL: CP000799
EMBL-CDS: ABV16438.1
RefSeq_NT: NC_009790.1
EnsemblGenome: EBESCG00000022778.
EnsemblGenome_TRS: EBESCT00000023724
EnsemblGenome_PRO: EBESCP00000022619
GenomeReviews: CP000799_GR
KEGG: ecw:EcE24377A_E0051
eggNOG: COG3468
HOGENOM: HBG467630
OMA: DIFNPAN
ProtClustDB: CLSK2392806
BioCyc: ECOL331111:ECE24377A_E0051-MONOMER
Taxonomy ID 331111
Plasmid No pETEC_74
Gene Starting Position 49305
Gene Ending Position 53405
Gene Strand (Orientation) +
Protein Name secreted serine peptidase EatA
DNA Sequence 
>gi|157149504:49305-53405 Escherichia coli E24377A plasmid pETEC_74, complete sequence
TATGAATAAAGTGTTCTCTCTTAAGTATAGTTTTTTAGCCAAAGGTTTTATTGCTGTTTCTGAACTTGCC
CGTCGCGTTTCTGTTAAAGGGAAACTGAAGAGTGCTTCATCAATAATTATTTCACCAATAACAATTGCTA
TTGTTTCTTATGCCCCCCCATCTCTTGCTGCAACAGTTAATGCAGATATATCGTATCAAACATTTCGGGA
TTTTGCCGAAAATAAAGGAGCTTTTATAGTTGGCGCATCAAATATAAATATCTACGATAAGAATGGAGTG
TTAGTTGGAGTGCTTGATAAAGCTCCAATGCCTGATTTTAGTAGTGCCACGATGAATACAGGGACATTAC
CACCAGGAGACCATACACTGTACTCACCTCAATATGTTGTCACAGCAAAGCATGTTAATGGATCAGATAT
AATGAGTTTTGGACATATTCAAAATAATTATACTGTAGTAGGAGAGAACAACCATAATAGCCTTGATATT
AAAACACGACGTTTAAATAAGATTGTCACGGAGGTCGCCCCTGCAGAAGTCTCCAGTGTTGGAGCTGTAA
ATGGCGCTTATCAAGAAGGGGGGCGTTTTACAGCCTTTTATAGGCTTGGAGGTGGATTGCAATATATAAA
GGATAAAAATGGAAATCTTACACCGGTATATACAAATGGTGGTTTCCTAACTGGAGGAACTATCAGTGCT
TTAAGCTCATATAACAATGGGCAAATGATTACTGCACCTACAGGAGATATTTTTAATCCTGCTAATGGGC
CTCTTGCAAACTATCTAAATAAAGGTGATAGTGGCTCTCCTTTATTTGCGTATGACTCTCTGGAAAAAAA
ATGGGTTTTAATTGGCGTTCTTTCATCAGGAAGTGAGTATGGTAATAACTGGGTTGTCACAACTCAAGAT
TTTCTTAATCAGCAACAAAAGCATGATTTTGATAAAACAATATCATATGACTCTAAAAAGGGGAGCTTAC
AATGGAGATATGATAAAGACGCAGGAGTGGGAACATTAAGTCAAGAGGGAGTTGTGTGGGACATGCATGG
AAAAAAAGGGGAAGACCTAAATGCAGGTAAAAATCTTCAATTTACAGGAAATAATGGAGAGGTTATTTTA
CACGACTCTATAGATCAAGGGGCTGGCTATCTGCAGTTTTTTAACAACTACACAGTTACATCCTTAACTG
ACCAAACATGGACCGGAGGTGGTATCATTACTGAAAAAGGTGTAAATGTGCTTTGGCAGGTTAATGGTGT
TAATAATGATAACTTACATAAAGTTGGTGAAGGCACATTAACTGTTAATGGAAAAGGGGTTAATAATGGA
GGACTGAAAGTCGGTGATGGAACCGTAATTCTGAATCAACGCCCTGATGATAATGGACACAAGCAAGCCT
TTAGCTCTATTAACATTTCCAGTGGTCGTGCAACAGTTATACTTTCAGATGCTAATCAAGTTAACCCAGA
TAAAATATCATGGGGATATAGAGGCGGCACTCTTGATTTAAATGGAAATAATGTAACCTTTACTCGTCTT
CAGGCTGCAGATTATGGTGCTATTATTTCTAACAATAACAATAACAAAAACAAATCTGAATTAACACTTA
AATTACAAACACTAAATGAAAATGACATTAGTGTTGATGTGAAGACATATGAAGTTTTTGGGGGGCGTGG
TAGTCCAGGTGACTTATATTATGTTTCTGCATCAAATACTTACTTTATCCTGAAATCAAAGGCGTACGGT
CCATTTTTCAGTGATTTAGATAATACCAATGTCTGGCAAAATGTTGGTCACGATCGTGATAAAGCGATTC
AAATCGTGAAACAGCAGAAGATTGAGGAAAGCTCTCAACCTTATATGTTTCATGGACAACTTAATGGTTA
TATGGATGTAAATATACATCCACTCTCTGGTAAGGATGTGCTGACTCTTGATGGTTCTGTTAATCTGCCT
GAAGGGGTGATAACGAAAAAGTCAGGTACTCTGATATTCCAGGGGCATCCGGTGATTCATGCTGGAATGA
CAACCTCAGCCGGCCAGAGTGATTGGGAAAACCGTCAGTTTACAATGGATAAACTGAAGCTTGATGCAGC
AACATTCCATCTCTCCAGAAATACTCGTATGCAAGGAGATATTAGTGCTGCCAACGGAAGTACCGTCATT
CTGGGAAGTTCTCGGGTCTTTACTGACAAGAATGATGGAACCGGTAATGCAGTATCTTCTGTTGAAGGGA
GTTCCACTGCAACAACAGCTGCTGACCAAAGTTATTACAGTGGTAATGTGCTGCTCGAAAACCATTCGTC
TCTGGAGGTCAGGGAGAATTTTACTGGTGGTATTGAGGCTTATGACAGTTCTGTTAGTGTGACCTCTCAG
AATGCTATTCTTGACCATGTTGGTAGCTTTATTAATAGTAGTCTGCTTCTCGAAAAAGGAGCAAAACTGA
CTGCACAGAGTGGTATTTTCACAAATAACACTATGGAAATAAAAGAAAACGCCTCTCTGACTCTGACAGG
GATCCCTTCTGTAGGAAAGCCGGGGTATTATTCACCTGTAATCTCGACTACAGAAGGAATTCATCTCGGT
GAGCGGGCCAGCCTTTCAGTGAAAAATATGGGCTATCTGAGTTCAAATATTATAGCAGAGGACTCTGCAG
CAATTATTAATCTGGGAGACAGTAATGCAACTATCGGGAAGACGGACTCTCCATTATTCAATACCTTAAT
GAGGGGATATAATGCTGTTTTGCAGGGCAATATTATGGGGCCACAGAGCTCAGTGAATATGAACAATGCT
CTGTGGCACTCTGATAGAAATTCGGAAATCAAAGAGCTGAAAGCCAACGACTCCCAAATAGAGTTAGGTG
GAAGAGGGCATTTTGCAAAACTGCGGGTAAAAGAGCTTATTGCGTCTAACTCAGTGTTTCTTGTACATGT
AAACAATGGCCAGGCTGACCAGTTGAATGTTACCGGCAAACTGCAGGGCAGCAATAATACTATTCTTGTT
AACTTTTTTAACAAAGCAGCCAATGGTACAAATGTGACGTTAATCACTGCACCAAAAGGCAGTGATGAAA
ATACATTCAAGGCCGGAACCCAGCAGATTGGATTCAGTAATATCACGCCAGAAATCAGGACAGAAAATAC
GGATACAGCCACAAAGTGGGTGCTGACTGGATATCAGTCTGTCGCTGATGCCAGAGCCTCGAAAATCGCA
ACGGACTTTATGGATTCAGGTTATAAATCCTTCCTGACGGAAGTCAATAATCTGAACAAACGTATGGGGG
ATTTACGGGATAGTCAGGGAGATGCTGGAGGGTGGGCGCGTATCATGAATGGTACCGGTTCAGGTGAGAG
TGGTTACAGAGATAACTATACCCACGTTCAGATTGGTGCAGACAGAAAGCATGAGCTGAACGGTCTAAAT
TTATTCACCGGTGCATTACTGACCTATACAGACAGCAATGCCAGCAGCCAGGCTTTCAGCGGTAAAACAA
AATCGCTAGGGGGAGGGGTGTATGCATCAGGTCTCTTTGAGTCTGGAGCTTATTTTGACCTGATTGGTAA
ATATCTCCATCATGATAATCGGTATACGTTGAATTTTGCCTCCCTGGGGGAAAGAAGCTATACCACCCAT
TCTTTGTATGCTGGAGCTGAAATCGGGTATCGTTATCACATGTCAGAAAATACATGGGTGGAACCACAGA
TGGAACTGGTTTATGGTTCGGTATCAGGAAAGTCATTTAACTGGAAAGACCAGGGAATGCAATTGAGTAT
GAAAGACAAAGACTATCACCCACTAATTGGTCGAACAGGCGTGGATGTAGGTAGAGTGTTCTCTGGAGAT
ACCTGGAAAGTAACAGCACGTGCAGGACTGAGTTACCAGTTCGATTTGCTGGCAAATGGAGAAACTGTTT
TACAGGATGCTTCTGGTAAAAAACACTTCAAAGGTGAAAAAGACAGCAGGATGCTAATGAACGTGGGAAC
GAATGTGGAAGTTAAAGACAATATGCGTTTTGGTCTGGAGTTGGAGAAGTCGGCGTTTGGGAGATATAAT
ATAGACAACTCTATAAATGCTAACTTCCGTTATTATTTCTG
Protein Sequence 
>gi|157149562|ref|YP_001451588.1| secreted serine peptidase EatA [Escherichia coli E24377A] MNKVFSLKYSFLAKGFIAVSELARRVSVKGKLKSASSIIISPITIAIVSYAPPSLAATVNADISYQTFRDFAENKGAFIVGASNINIYDKNGVLVGVLDKAPMPDFSSATMNTGTLPPGDHTLYSPQYVVTAKHVNGSDIMSFGHIQNNYTVVGENNHNSLDIKTRRLNKIVTEVAPAEVSSVGAVNGAYQEGGRFTAFYRLGGGLQYIKDKNGNLTPVYTNGGFLTGGTISALSSYNNGQMITAPTGDIFNPANGPLANYLNKGDSGSPLFAYDSLEKKWVLIGVLSSGSEYGNNWVVTTQDFLNQQQKHDFDKTISYDSKKGSLQWRYDKDAGVGTLSQEGVVWDMHGKKGEDLNAGKNLQFTGNNGEVILHDSIDQGAGYLQFFNNYTVTSLTDQTWTGGGIITEKGVNVLWQVNGVNNDNLHKVGEGTLTVNGKGVNNGGLKVGDGTVILNQRPDDNGHKQAFSSINISSGRATVILSDANQVNPDKISWGYRGGTLDLNGNNVTFTRLQAADYGAIISNNNNNKNKSELTLKLQTLNENDISVDVKTYEVFGGRGSPGDLYYVSASNTYFILKSKAYGPFFSDLDNTNVWQNVGHDRDKAIQIVKQQKIEESSQPYMFHGQLNGYMDVNIHPLSGKDVLTLDGSVNLPEGVITKKSGTLIFQGHPVIHAGMTTSAGQSDWENRQFTMDKLKLDAATFHLSRNTRMQGDISAANGSTVILGSSRVFTDKNDGTGNAVSSVEGSSTATTAADQSYYSGNVLLENHSSLEVRENFTGGIEAYDSSVSVTSQNAILDHVGSFINSSLLLEKGAKLTAQSGIFTNNTMEIKENASLTLTGIPSVGKPGYYSPVISTTEGIHLGERASLSVKNMGYLSSNIIAEDSAAIINLGDSNATIGKTDSPLFNTLMRGYNAVLQGNIMGPQSSVNMNNALWHSDRNSEIKELKANDSQIELGGRGHFAKLRVKELIASNSVFLVHVNNGQADQLNVTGKLQGSNNTILVNFFNKAANGTNVTLITAPKGSDENTFKAGTQQIGFSNITPEIRTENTDTATKWVLTGYQSVADARASKIATDFMDSGYKSFLTEVNNLNKRMGDLRDSQGDAGGWARIMNGTGSGESGYRDNYTHVQIGADRKHELNGLNLFTGALLTYTDSNASSQAFSGKTKSLGGGVYASGLFESGAYFDLIGKYLHHDNRYTLNFASLGERSYTTHSLYAGAEIGYRYHMSENTWVEPQMELVYGSVSGKSFNWKDQGMQLSMKDKDYHPLIGRTGVDVGRVFSGDTWKVTARAGLSYQFDLLANGETVLQDASGKKHFKGEKDSRMLMNVGTNVEVKDNMRFGLELEKSAFGRYNIDNSINANFRYYF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: interruption of the eatA gene retarded fluid accumulation in the rabbit ileal loop model, suggesting that this autotransporter contributes to the virulence of ETEC (Patel et al., 2004).
COG COG3468MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Patel et al., 2004: Patel SK, Dotson J, Allen KP, Fleckenstein JM. Identification and molecular characterization of EatA, an autotransporter protein of enterotoxigenic Escherichia coli. Infection and immunity. 2004; 72(3); 1786-1794. [PubMed: 14977988].