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iucA from Escherichia coli APEC O1

Victor ID 2288
Gene Name iucA from Escherichia coli APEC O1
Sequence Strain (Species/Organism) Escherichia coli APEC O1
NCBI Gene ID 5616680
NCBI Protein GI 157418256
Locus Tag APECO1_O1CoBM172
Protein Accession YP_001481328.1
Other Database IDs UniProtKB-ID: Q27T49_ECOK1
UniRef100: UniRef100_B7JCC1
UniRef90: UniRef90_Q47316
UniRef50: UniRef50_Q47316
UniParc: UPI00006C9BD4
EMBL: DQ381420
EMBL-CDS: ABD51743.1
RefSeq_NT: NC_009837.1
EnsemblGenome: EBESCG00000039002.
EnsemblGenome_TRS: EBESCT00000039952
EnsemblGenome_PRO: EBESCP00000038303
GenomeReviews: DQ381420_GR
eggNOG: COG4264
HOGENOM: HBG578705
OMA: SFLNCYL
ProtClustDB: CLSK908239
BioCyc: ECOL405955:APECO1_O1COBM172-MONOMER
Taxonomy ID 405955
Plasmid No pAPEC-O1-ColBM
Gene Starting Position 147691
Gene Ending Position 149472
Gene Strand (Orientation) -
Protein Name aerobactin siderophore system, aerobactin synthetase; similar to ABA54740; identified by match to protein family HMM PF04183
DNA Sequence 
>gi|157418083:147691-149472 Escherichia coli APEC O1 plasmid pAPEC-O1-ColBM, complete sequence
TTCAGACCTCCTGAGCCTGCAGCGGGTTAGCGAAATCAAAATAGATCACCGAAGGGTCAACGATGGTGTT
CTCGTTATGATCGTTCAGATAACAGAAAAAGTTACCTTTTACGTTCCAGTACGGACTTTCCAGAACATAG
TTGAGACAGGTTTTATGAGTCACCTGGTCACGCACTTCAGCCAGCAATGTTCGTACACGAGCCATCAGAT
TCGCTTCGCTGTCCAGCCCGGCAGCACCCAGCGCAGCAGTTACGGCAAAAGTGGAGTTAACCAGCAGGTA
ATAAGGGAAATAGCGCAGCAACTGCTCACGGGTGAAAATATTTTCCGCCTGCGCCTCGTCAATGGTATCG
AGCCACTCTGTCGCGTGAGGCATAAACGCGCTGCCCTGGCAGTCACGGTAAATAAATCCGACCGGCAGAT
CCCCAAGCATCTGCACAAGAATATTTTGCTGATGCGCCAGCAGCACCAGGCCGTAATCCGCTTCAGCCGT
AAACAGAGGCTTCAGCACCTGCTGACAGTAAGCATCGACCCATGCGTGGGCGGCCTGTTGCACAGTGATA
CCGAGGCGATCGCTCAGGCGTTTTACCGCCGAAACCAGCAGCGAATCACCGCCATCCGGTGCGGCCTGAG
TCAGGGAAACCAGAACGTTGGTCTGGCTTTGCGGCTGCTCCAGCAGCAGGTTTTCACGCAGGGAAAACAA
ACTTTCCTGCATGATGTTGCCGTTAAGATCGCGCAGCCCGGCCCAGCCGTCCTCCTGCATTACCCGGAAA
GTAGGGAAGCGGGCCTGTAGCATCTGCCAGCCGTCGGTTTGCGCCAGACGTGCCAGGCGCATTCCTCGCT
CCACCTCTTTCACAGACAGAGTACGGACGGAGTTGGTCAGCCGAACGCTCAGGGAGAACTTGATCATATC
GCGGCTGGTAGCACAGTAGAGGGAGCGGGAAGAGGTGGTCGGCAGCCACGACGTGCCGGCCTCGCCTAAG
TCTCTGATAAGTCCTTTAGCAAAAAGTGCCTGGCACCACACTTGCTGCAAAAGATATTCTCCCTGCCACG
GGTGCAGCGGGAACAGCCATTGATTGTCACTTAATTCGTTGAGTAACTGGGGCGCATTTTCTGCGGCAAA
TCGCGTCAACCGCTGTTGAAGGTTAAGATGCAGACTTTCACCAGCGATTTGCGTTTTATCCACCGAAAAC
CACCGCAGCGGGAAGTGAGGTGCCATGTCAGGCAGGTATCGTTCAGCTTCCTGGCGGTTAAACGGTTCAT
GAGACTTAGGTGCAGGGTGGAAAGCGTGTCCTGTCAGCAGTGCCTGCTCAGCCTCGCCAAAATTCAACGC
TTTTTCACGCAGGATGGCCCAGTCATGGCGGGCATCAATTGTCTGTTGCGTATGGGCGTAGCTTTCCAGC
ACGCGTTGGTGGAAAGTTTCGCAGAGGGGAACTGGCAGAAAAAGTTGATGCCGGAGCTTATCAATAATAA
GCCGGGAGAGAGTGGTAAAGTCGACAGGATAACTGCCTGATGCCGTGACCAGATGAGCAGGAAATGCAAA
GCGGTGATGCTGGGTTGGGGAGAAATAAGCCACTCTGAAATGGAGCGACTTCTGTTCGTCCAGCGGGATA
ATCAATTCGTCTGGCGGGTATTCCGCCAGTTGCCAGTCTTTGGTTTCACGAATCAAGGCATTCAGGAAGC
ACTGCGCAGCCACATCTGTGGCGGATTTTTCAGAGGGCAGGATCATAATCAAACAGCTCCTACACAGTAA
AATAATAACAATTATGTCAATAATGATTCTCA
Protein Sequence 
>gi|157418256|ref|YP_001481328.1| IucA [Escherichia coli APEC O1] MRIIIDIIVIILLCRSCLIMILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDLNGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (de and Martinez, 1988).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
de and Martinez, 1988: de Lorenzo V, Martinez JL. Aerobactin production as a virulence factor: a reevaluation. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1988; 7(5); 621-629. [PubMed: 2973985].