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iucC from Escherichia coli APEC O1

Victor ID 2287
Gene Name iucC from Escherichia coli APEC O1
Sequence Strain (Species/Organism) Escherichia coli APEC O1
NCBI Gene ID 5616678
NCBI Protein GI 157418254
Locus Tag APECO1_O1CoBM170
Protein Accession YP_001481326.1
Other Database IDs UniProtKB-ID: Q27T51_ECOK1
UniRef100: UniRef100_Q3L7J3
UniRef90: UniRef90_Q47318
UniRef50: UniRef50_Q47318
UniParc: UPI0000505217
EMBL: DQ381420
EMBL-CDS: ABD51741.1
RefSeq_NT: NC_009837.1
EnsemblGenome: EBESCG00000038979.
EnsemblGenome_TRS: EBESCT00000039929
EnsemblGenome_PRO: EBESCP00000038280
GenomeReviews: DQ381420_GR
eggNOG: COG4264
HOGENOM: HBG417345
OMA: PNPLYRA
ProtClustDB: CLSK888707
BioCyc: ECOL405955:APECO1_O1COBM170-MONOMER
Taxonomy ID 405955
Plasmid No pAPEC-O1-ColBM
Gene Starting Position 145001
Gene Ending Position 146758
Gene Strand (Orientation) -
Protein Name aerobactin siderophore system, aerobactin biosynthesis protein; similar to ABA54742; identified by match to protein family HMMPFO4183
DNA Sequence 
>gi|157418083:145001-146758 Escherichia coli APEC O1 plasmid pAPEC-O1-ColBM, complete sequence
TTCATGATTCATATTCCTGAGTTACCAGCCACAGCGGATTTTGCAGATCCTCAAGGTAATTCGGCAGCAT
GCGGCTGCCGCCATCCAGATCAGGCCAGGTCAGTTTTACCGGGTTCAGCACCACGCGAATGATTTGTGGC
CTGAAAAGTGAGAAAAGCGCAAAACGCTCTGACATTTGTGGATGTTTTTTCATGTAATCACTCAACACTG
CTGCCAGCAGTTGATAAAATCGCCTTTCAGGTACGCCAAGACGAACCATCAGTGGCGAAATAAAACGCAG
TACTGTCACGAAGTGACCCGTCTGCAAATCATGGATTAAGTAGTCCGCACTCAGGCGGGATGTAACATCA
CGAACCTCCTGAGGCAAAGAGTCCATTTCGGGGAACTCTTCTTTCACCAGTCGCATATCGCCCTGGAAGT
CTTTCAGCAGAACACGCTGTGGAACCCCCTCTTTCATGGCGAGAGTTATATTTTGTCCATGTGCAATAAG
CGCGACACCGTAGCGGCAAAGCAGGTGATACAGAGGAACCACGACCACCCGGAACAGTTGCGTAAGCCAG
GTTTCAGCGTCCAGCCCGGAGCGGTCTATATATGCGCCTGCCAGCGGCTGATTGTTTTCGTCGCACTCCA
TCAGTGTTGCCATCAGAACCGGACTTTCATCCGGTTTCAGCCAGCGGCACGGATTCTCCCGCCAGATAAC
ACCAAGCATTTCCTGGTAGCGATAGGGAGCCCGGGCAAGCGCGGCATAGCCTTCATGGGAGACATAGCCT
GCAGCCGGTTCACCAAGTATCACTGCGCCGCTTTGCACTAGGGTGGCGTCGGTCGCAAAAACCTGTTGTA
GCCAGCGTGAAGCCAGTGGTCCGGCAGCGATGTATCTGCCAGGGATCCCCCGGTAGCATGAGGTGTTGTA
GATGGTCAGCGGCAGCTTGATATCCAGCCCGCCCCGGCGACTGGCGTTGGTCAGGGTACGCAGCGACTGC
TGGGCGAGCCACTGGTCGCCAAACTCGCCGAGAGACACCATCCTGCCTTCGGCAAAATCAGCGATGAAGT
CGGTAGCGATTTTTTGCTGCCACTGCCACGGATGTACCGGCAGCGGCAGCCAGTTATGATCCAGTCCGTT
TTCCTGCCAGACCTGACTGAAGCGGGCAAACTCCTGCGGATCCATTGCGGCCGTCAACAACTGATGAATA
TCCATCTCGTTATCACAGCGCCAGATCATATGTTCACGTTTTACCGCCAGCCAGTGCAGTCTGAAGGTGT
TGGCATACTCTGGCGCATATCGTTCCAGCGCCTCTTTACCCCAGCCACGGCGACCTTTATTAAAAACGAA
TTTAGGATGACCGCTCAGCAGGCATTGCAGGCGGTCGGCATTAAGATTAATCAGGTCACTGGCGCTCAGC
CCGCGACGGGCTTTCAGTAGTTGCAGGTCGCCCAGCAGCGTGGCATACAAATCCTGCATATGCTCAGCAA
CGGTTGCATCGCTCATTGACAGTACCTGCTTTAGCTGCATCAGCAGCGTCTGAGCCAGTACTGGCTCGTC
CGCGCAGCGCAGAGTTTGAGCATCAATCCAGAGCCAGCCCCAGATACCACGTTCAGCGATGAAGCGCCAT
TGTGCTCCCGGCAGGTTAATGCAGTAGCGGTCATCGCCCTGAGATTCCGCGTGGAAAACCTGCTCATACT
CCAGCTCAGACAACATTTTTGCCACCAGGCGGCGGTTGACCAAATCCCAGTCTTTGTGATTCATTACAGA
CCGACCTC
Protein Sequence 
>gi|157418254|ref|YP_001481326.1| IucC [Escherichia coli APEC O1] MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (de and Martinez, 1988).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
de and Martinez, 1988: de Lorenzo V, Martinez JL. Aerobactin production as a virulence factor: a reevaluation. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1988; 7(5); 621-629. [PubMed: 2973985].