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iutA from Escherichia coli APEC O1

Victor ID 2285
Gene Name iutA from Escherichia coli APEC O1
Sequence Strain (Species/Organism) Escherichia coli APEC O1
NCBI Gene ID 5616676
NCBI Protein GI 157418252
Locus Tag APECO1_O1CoBM168
Protein Accession YP_001481324.1
Other Database IDs UniProtKB-ID: Q27T53_ECOK1
UniRef100: UniRef100_B1P7H4
UniRef90: UniRef90_B1P7H4
UniRef50: UniRef50_P14542
UniParc: UPI00006C9BD1
EMBL: DQ381420
EMBL-CDS: ABD51739.1
RefSeq_NT: NC_009837.1
EnsemblGenome: EBESCG00000038932.
EnsemblGenome_TRS: EBESCT00000039882
EnsemblGenome_PRO: EBESCP00000038233
GenomeReviews: DQ381420_GR
eggNOG: COG1629
HOGENOM: HBG303715
OMA: FYSPTYG
ProtClustDB: CLSK868823
BioCyc: ECOL405955:APECO1_O1COBM168-MONOMER
Taxonomy ID 405955
Plasmid No pAPEC-O1-ColBM
Gene Starting Position 141444
Gene Ending Position 143654
Gene Strand (Orientation) -
Protein Name aerobactin siderophore system, ferric aerobactin receptor protein; similar to ABA54744; identified by match to protein family HMM PF00593
DNA Sequence 
>gi|157418083:141444-143654 Escherichia coli APEC O1 plasmid pAPEC-O1-ColBM, complete sequence
GTCAGAACAGCACAGAGTAGTTCAGACCAAAGGTTCGGCCCCTGCCTTTGTAGTCGTACAGTGACGCTGG
GCCGTAACCCGGGCTGTAGTACAGTGGTGCACGCTGCCCCCAGACAGTGGTGTAGTCACGGTCGAAGAGG
TTTTCAATGCTGAAGCTGAGTGTACCCACCGGAAGCTGATAACTGCCGAGCAGATCCGCGGTGGTATAGC
CATCGACCTTGTAGCCCTGCGCGTCGCTCACGTCAAAGGAGGTGGTGCTCTGCACGCGCAGACTCCACGG
GTCCGGTGCCCAGCCAATGTAGGCTGTCGCTTTTGATGGGCTTGCTGTCTTCACATCGTATTTCTGCCAG
GTACCGTTCACTTTCGACTCAGTTTTCAGCACGTTGAAGTTCACTCCGGTACTCCAGTCAGTATCAGGAA
TCAGGTAGTCCACCGCACCTTCCACGCCGTAAATACGGCGTTTGTCGTCCACCACGCTGATGGTCAGATC
TTTATTCGCCACCACGCTCTTATCAGAAATCGAATAGTAGGCCGCGATTTGGGTACGCAGATTATTGCCA
GTAAAGCGCCAGCCCAGCTCATAAGAATCGACTTTCACGCCTTCCAGCTTGCTGTCGCTGACGTTCACAC
TCTTTGTTAGAGGAAGATGGCCGTTCACTGCAGCACCATAGATGCCGCGACCATAGTATTTACCCGGGTC
CGGCAGCTCCACGCCCTGGGAGAAGTTGAGCCATGCCTGCTGGCGTTCGGTGATGTGCATCAGCAGACCG
GCGTTGAACAGGAAGTTGTCGTAATCGACTGAGCCGCCAGGAATGGCGTCGGCGGATGTAGCCTTCCCGG
CGGCAATCTGCCGTTGCTGCGCGTAGCCGATGAAATCATCAATCTTGTTTTCAGTGTACTGATAGCGTAC
GCCACCGTTGAGGGTAAAGAGATTATTGATGTCATAGCCTGATTGCAGGAAGGCCGCCAGGTTGGTGATG
TCATACGACGGATAGCGCCCGGTGGTGTAAATCTTCTTGTTGTTCAGCCCTCCGGAAGCGCTTGCCTGAG
CCAGGTCGAAGAACATCTGGTTGGAGGTAAAGCGCTCATGATCAGCATCCAGCCCCCAGGTGATTTGCCA
GCCGTCCATCGGTTTGCTGTTCAGAGTCAGTTTCATGCCGTACTGGTCGGTGTCCTGCTGTGACGAAGAG
AAAGCCGTCACCTGTTTGTTCGCATTTACCGTCGGGAACGGGTAGAATCGCAACGACTCATCGCGGTAGT
AAACCTGACCGACCAGCTCCTGTCCCAGAAAAGCGCTGTCAGAGTACTGCAGGCTGATCAAATGCCGCTC
AGTGCCGGGAATACGGTCGGAATTCAGCCCGTTACTGACGAATGGCGTGCTGGTCCCTCTGATGGCAGAG
AAGCCTTTCCCGAGATTAAGCCCGTAATCGTCGTCGCCCTGGCTTTTATAGTACTGTGTGATCAACTGAA
GCTGCCGGGATTCATCGATGTTCAGCGTACCAGTTCCCATGATGTCCAGCCGATCGGAGTACTGCAGGCC
GGTCTGGGTGTTATCAAGCAAGGTGGCATCGCCGTTACCGTCAAACCAGCCGCCAAATTTCTGATATGCC
ACGGAAAGACGTCCGGAGATATGCTCATTTCCGCCGGAGACAGCTCCGGCAATGCGTTCATCGTGATCTT
TACTGCTGCTAAAGCCACTTTTGGTGCCAGCCTCAAACTCCATCATGGTTTCCGGCTGGCCTTTTTTGGT
CACGATGTTGATCAGGCCACCGGTACTGCCGCCGCCGTACAGGGACGTCGCACCGGAGATCACTTCAATA
TGGTCGATATTAAAAGGATCTATAGAGTCCAGTTGTCGGCTGTCGGTACGTGAAGAGTTGAGACGCACGC
CGTCAACCAGCACGACCAGCGGGCGGCCACGCACATTCATACCGTAGTTGGTGCGGCTCCGGCTGCTGAC
GTCAAGGCCAGGGATCAGCTGAGCCAGTGCGTCTTTAAGCTCTTTGCCGCCCTGAATCTGCTGTTCCAGT
TCGGCGTTTTCGATAACCCAGGTGGTTTGCGCCATCTCCGCTACGGTGCGATTGCTGCGGTTGGCAGACA
CCACGAACGTTTCATCATCGGTTTGTTGAGCGACTGCTGGCGCCATCATGGTAAGAAGCAGTGGGTTGAG
AGCCCAAAGCGTATACTTTTTGCTTATCATCATTATTCCTC
Protein Sequence 
>gi|157418252|ref|YP_001481324.1| IutA [Escherichia coli APEC O1] MMISKKYTLWALNPLLLTMMAPAVAQQTDDETFVVSANRSNRTVAEMAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDVSSRSRTNYGMNVRGRPLVVLVDGVRLNSSRTDSRQLDSIDPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQPETMMEFEAGTKSGFSSSKDHDERIAGAVSGGNEHISGRLSVAYQKFGGWFDGNGDATLLDNTQTGLQYSDRLDIMGTGTLNIDESRQLQLITQYYKSQGDDDYGLNLGKGFSAIRGTSTPFVSNGLNSDRIPGTERHLISLQYSDSAFLGQELVGQVYYRDESLRFYPFPTVNANKQVTAFSSSQQDTDQYGMKLTLNSKPMDGWQITWGLDADHERFTSNQMFFDLAQASASGGLNNKKIYTTGRYPSYDITNLAAFLQSGYDINNLFTLNGGVRYQYTENKIDDFIGYAQQRQIAAGKATSADAIPGGSVDYDNFLFNAGLLMHITERQQAWLNFSQGVELPDPGKYYGRGIYGAAVNGHLPLTKSVNVSDSKLEGVKVDSYELGWRFTGNNLRTQIAAYYSISDKSVVANKDLTISVVDDKRRIYGVEGAVDYLIPDTDWSTGVNFNVLKTESKVNGTWQKYDVKTASPSKATAYIGWAPDPWSLRVQSTTSFDVSDAQGYKVDGYTTADLLGSYQLPVGTLSFSIENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKGRGRTFGLNYSVLF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Torres et al., 2001).
COG COG1629P, under P: Inorganic ion transport and metabolism
References
Torres et al., 2001: Torres AG, Redford P, Welch RA, Payne SM. TonB-dependent systems of uropathogenic Escherichia coli: aerobactin and heme transport and TonB are required for virulence in the mouse. Infection and immunity. 2001; 69(10); 6179-6185. [PubMed: 11553558].