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iroN from Escherichia coli APEC O1

Victor ID 2281
Gene Name iroN from Escherichia coli APEC O1
Sequence Strain (Species/Organism) Escherichia coli APEC O1
NCBI Gene ID 5616645
NCBI Protein GI 157418221
Locus Tag APECO1_O1CoBM137
Protein Accession YP_001481293.1
Other Database IDs UniProtKB-ID: Q27T84_ECOK1
UniRef100: UniRef100_Q8GH18
UniRef90: UniRef90_Q93K73
UniRef50: UniRef50_Q05098
UniParc: UPI00000BFD7B
EMBL: DQ381420
EMBL-CDS: ABD51708.1
RefSeq_NT: NC_009837.1
EnsemblGenome: EBESCG00000038881.
EnsemblGenome_TRS: EBESCT00000039831
EnsemblGenome_PRO: EBESCP00000038182
GenomeReviews: DQ381420_GR
eggNOG: COG4771
HOGENOM: HBG464298
OMA: TMVVEST
ProtClustDB: PRK13528
BioCyc: ECOL405955:APECO1_O1COBM137-MONOMER
Taxonomy ID 405955
Plasmid No pAPEC-O1-ColBM
Gene Starting Position 113563
Gene Ending Position 115751
Gene Strand (Orientation) +
Protein Name salmochelin siderophore system, salmochelin receptor; similar to AAS80269; identified by match to protein family HMM PF00593
DNA Sequence 
>gi|157418083:113563-115751 Escherichia coli APEC O1 plasmid pAPEC-O1-ColBM, complete sequence
TAGGGAATAGGTATGAGAATTAACAAAATCCTCTGGTCGCTAACTGTGCTCCTGGTTGGGTTGAATAGCC
AGGTATCAGTAGCCAAATCCTCCGACGATGATAATGACGAGACTCTGGTGGTGGAAGCCACCGCTGAGCA
GGTATTAAAACAGCAGCCGGGCGTGTCGGTTATTACCAGCGAGGATATTAAAAAGACCCCTCCGGTAAAC
GACCTTTCAGATATTATTCGTAAAATGCCTGGCGTCAATCTTACCGGCAATAGCGCCTCGGGCACACGCG
GTAACAACCGCCAGATCGATATTCGTGGTATGGGGCCGGAAAACACCTTAATTTTAATTGATGGTGTACC
GGTGACGTCACGTAACTCCGTGCGTTATAGCTGGCGTGGAGAGCGTGATACCCGCGGTGACACCAACTGG
GTGCCACCGGAACAGGTTGAGCGTATTGAAGTGATCCGCGGCCCTGCGGCGGCGCGCTACGGTTCGGGGG
CAGCCGGGGGGGTGGTGAACATCATTACCAAACGTCCCACCAACGACTGGCACGGTTCGCTGTCGTTATA
CACCAATCAGCCGGAAAGTAGCGATGAGGGCGCTACGCGTCGCGCCAATTTCAGCCTTAGTGGGCCTCTG
GCTGGTAATGCTCTTACCACGCGTTTGTATGGTAACCTGAATAAAACGGATGCTGACAGTTGGGATATTA
ATTCTCCGGTCGGTACGAAAAACGCAGCCGGGCATGAAGGGGTACGTAACAAAGATATTAACGGCGTTGT
CTCGTGGAAATTAAATCCGCAGCAGATTCTCGATTTCGAAGCCGGATATAGCCGCCAGGGGAATATCTAT
GCGGGCGATACGCAAAACAGTTCTTCCAGTGCAGTTACCGAAAGCCTGGCAAAATCCGGCAAAGAGACGA
ACCGCCTGTACCGACAGAATTATGGCATTACGCATAATGGTATCTGGGACTGGGGACAAAGTCGCTTTGG
TGTTTATTACGAGAAAACCAATAATACCCGCATGAATGAAGGATTATCCGGCGGTGGTGAAGGGCGTATT
TTAGCGGGTGAAAAGTTTACGACCAATCGCCTGAGTTCCTGGCGAACCAGCGGCGAGCTTAATATTCCTT
TGAATGTGATGGTTGATCAAACGCTGACCGTTGGTGCAGAGTGGAACCGCGATAAGCTCGATGATCCTTC
CTCTACCAGCCTGACGGTGAATGACAGTGATATCAGCGGTATTTCTGGCTCTGCTGCGGATCGCAGCAGT
AAAAATCATTCTCAAATCAGTGCGCTGTATATTGAAGATAACATTGAGCCGGTTCCTGGCACGAATATCA
TTCCCGGCCTGCGCTTTGATTATCTCAGCGACTCCGGCGGGAACTTCAGCCCCAGTCTGAATCTTTCGCA
GGAATTGGGCGATTATTTCAAAGTCAAAGCAGGGGTTGCCCGAACCTTTAAAGCCCCAAACCTGTATCAA
TCCAGTGAAGGCTATCTGCTCTACTCGAAAGGCAATGGCTGTCCAAAAGATATTACATCAGGCGGGTGCT
ACCTGATCGGTAATAAAGATCTCGATCCGGAAATCAGCGTCAATAAAGAAATTGGGCTGGAGTTCACCTG
GGAAGATTACCACGCAAGTGTGACCTACTTCCGCAATGATTACCAGAATAAGATCGTGGCCGGGGATAAC
GTTATCGGGCAAACCGCTTCAGGCGCATATATCCTCAAGTGGCAGAATGGCGGGAAAGCTCTGGTGGACG
GTATCGAAGCCAGTATGTCTTTCCCACTGGTGAAAGATCGTCTGAACTGGAATACCAATGCCACATGGAT
GATCACTTCGGAGCAAAAAGACACCGGTAATCCTCTGTCGGTCATCCCGAAATATACTATCAATAACTCG
CTTAACTGGACCATCACCCAGGCGTTTTCTGCCAGCGTCAACTGGACGTTATATGGCAGACAAAAACCGC
GTACTCATGCGGAAACCCGCAGTGAAGATACTGGCGGTCTGTCAGGTAAAGAGCTGGGCGCTTATTCACT
GGTGGGGACGAACTTCAATTACGATATTAATAAAAATCTGCGTCTTAATGTCGGCGTCAGTAATATCCTC
AATAAACAGATCTTCCGATCTTCTGAAGGGGCGAATACCTATAACGAGCCAGGCCGGGCTTACTATGCCG
GAGTTACCGCATCATTCTG
Protein Sequence 
>gi|157418221|ref|YP_001481293.1| outer membrane receptor FepA [Escherichia coli APEC O1] MRINKILWSLTVLLVGLNSQVSVAKSSDDDNDETLVVEATAEQVLKQQPGVSVITSEDIKKTPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGNALTTRLYGNLNKTDADSWDINSPVGTKNAAGHEGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGKETNRLYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILAGEKFTTNRLSSWRTSGELNIPLNVMVDQTLTVGAEWNRDKLDDPSSTSLTVNDSDISGISGSAADRSSKNHSQISALYIEDNIEPVPGTNIIPGLRFDYLSDSGGNFSPSLNLSQELGDYFKVKAGVARTFKAPNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKDLDPEISVNKEIGLEFTWEDYHASVTYFRNDYQNKIVAGDNVIGQTASGAYILKWQNGGKALVDGIEASMSFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLNWTITQAFSASVNWTLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNILNKQIFRSSEGANTYNEPGRAYYAGVTASF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iroA gene cluster mutants were unable to resist Lcn2 in mouse serum (Fischbach et al., 2006).
COG COG4771P, under P: Inorganic ion transport and metabolism
References
Fischbach et al., 2006: Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, Aderem A, Smith KD. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(44); 16502-16507. [PubMed: 17060628].