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hlyA from Escherichia coli O157:H7 str. Sakai

Victor ID 2275
Gene Name hlyA from Escherichia coli O157:H7 str. Sakai
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. Sakai
NCBI Gene ID 1789686
NCBI Protein GI 10955283
Locus Tag pO157p18
Protein Accession NP_052624.1
Other Database IDs UniProtKB-ID: Q46716_ECO57
UniRef100: UniRef100_Q0E868
UniRef90: UniRef90_A1EAA3
UniRef50: UniRef50_P55129
UniParc: UPI00000B51F9
EMBL: AF074613
EMBL: AB011549
EMBL-CDS: AAC70116.1
EMBL-CDS: BAA31774.1
RefSeq_NT: NC_002128.1
RefSeq_NT: NC_007414.1
EnsemblGenome: EBESCG00000028457.
EnsemblGenome_TRS: EBESCT00000029407
EnsemblGenome_PRO: EBESCP00000028112
EnsemblGenome: EBESCG00000059797.
EnsemblGenome_TRS: EBESCT00000060750
EnsemblGenome_PRO: EBESCP00000058394
GenomeReviews: AB011549_GR
GenomeRev
Taxonomy ID 386585
Plasmid No pO157
Gene Starting Position 16611
Gene Ending Position 19607
Gene Strand (Orientation) +
Protein Name hemolysin A
DNA Sequence 
>gi|10955266:16611-19607 Escherichia coli O157:H7 str. Sakai plasmid pO157, complete sequence
TATGACAGTAAATAAAATAAAGAACATTTTCAATAATGCGACATTGACTACAAAATCAGCATTTAATACA
GCATCATCAAGCGTACGTTCCGCTGGAAAAAAACTCATATTATTAATACCTGATAATTATGAAGCTCAGG
GCGTGGGTATTAATGAGTTGGTCAAAGCTGCTGATGAGCTTGGAATAGAAATACACCGTACTGAACGAGA
TGATACAGCGATTGCAAACCAGTTTTTTGGTGCAGCAGAAAAAGTTGTAGGATTAACTGAACGTGGTGTT
GCAATATTCGCACCACAACTTGACAAACTTCTGCAGAAGTATCAGAAAGTTGGGAGTAAAATAGGAGGAA
CCGCTGAAAATGTAGGTAATAATCTGGGAAAAGCCGGAACAGTTCTCTCAGCACTACAGAATTTTACGGG
GATTGCTTTATCAGGCATGGCTCTTGATGAATTGCTGAGAAAACAACGGGAAGGAGAGGATATAAGTCAG
AATGATATTGCCAAAAGTAGTATTGAACTTATTAATCAGCTTGTAGATACAGTATCAAGTATAAACAGTA
CCGTTGATTCATTTTCTGAGCAGCTTAACCAGCTTGGCTCATTTTTATCCAGTAAACCTCGATTAAGTTC
TGTTGGTGGGAAATTACAAAATTTACCAGACCTGGGCCCCCTGGGGGATGGGCTGGATGTTGTCTCCGGA
ATTCTTTCTGCTGTATCAGCAAGCTTTATTCTGGGAAACAGTGACGCACATACAGGAACAAAAGCTGCAG
CGGGTATCGAACTGACAACTCAGGTTCTTGGAAATGTTGGTAAAGCTGTTTCGCAATATATTCTGGCTCA
GAGAATGGCACAGGGGTTATCGACAACAGCTGCAAGTGCGGGTCTGATCACATCGGCTGTTATGCTGGCT
ATCAGTCCTCTTTCTTTCCTGGCTGCTGCAGATAAATTTGAGCGAGCTAAGCAGCTTGAATCATATTCTG
AACGATTTAAAAAATTGAATTATGAAGGGGATGCTTTACTCGCAGCCTTTCATAAAGAAACCGGAGCTAT
AGATGCAGCCCTGACAACAATAAATACTGTCCTGAGTTCTGTATCTGCGGGAGTTAGTGCAGCCTCCAGT
GCATCCCTCATAGGGGCCCCGATAAGCATGCTGGTGAGTGCATTAACCGGTACGATATCTGGCATTCTGG
AAGCATCAAAACAGGCTATGTTTGAGCACGTTGCAGAGAAATTCGCTGCTCGGATCAATGAATGGGAAAA
GGAGCATGGCAAAAATTATTTTGAGAATGGATATGACGCAAGACATGCTGCGTTTTTAGAAGACTCTCTG
TCTTTGCTTGCTGATTTTTCTCGTCAGCATGCAGTAGAAAGAGCAGTCGCAATAACCCAGCAACATTGGG
ATGAGAAGATCGGTGAACTTGCAGGCATAACCCGTAATGCTGATCGCAGTCAGAGTGGTAAGGCATATAT
TAATTATCTGGAAAATGGAGGGCTTTTAGAGGCTCAACCGAAGGAGTTTACACAACAAGTGTTTGATCCT
CAAAAAGGGACCATAGACCTTTCAACAGGTAATGTATCAAGTGTTTTGACATTTATAACACCAACATTTA
CCCCAGGAGAAGAAGTTAGAGAAAGAAAACAGAGTGGTAAATATGAATATATGACATCTCTTATTGTAAA
TGGTAAGGATACATGGTCTGTAAAAGGCATAAAAAATCATAAAGGTGTATATGATTATTCAAAATTGATT
CAGTTTGTTGAAAAGAATAACAAACACTATCAGGCGAGAATAATTTCTGAGCTCGGAGATAAAGACGATG
TGGTTTATTCTGGAGCAGGCTCATCAGAAGTATTTGCTGGTGAAGGTTATGATACCGTATCTTATAATAA
GACGGATGTTGGTAAACTAACAATTGATGCAACAGGAGCATCAAAACCTGGTGAGTATATAGTTTCAAAA
AATATGTATGGTGACGTGAAGGTATTGCAGGAAGTCGTTAAGGAACAGGAGGTGTCAGTAGGGAAGCGAA
CAGAGAAAATACAATATCGTGATTTTGAATTCAGAACCGGTGGAATTCCTTATGATGTAATAGATAATCT
TCATTCTGTTGAAGAGCTCATTGGCGGAAAACATGATGATGAATTCAAAGGCGGTAAGTTTAATGATATA
TTCCATGGCGCAGATGGGAACGATTATATCGAAGGTAATTATGGTAATGATCGACTATACGGCGATGATG
GGGATGATTATATATCCGGAGGACAGGGAGACGACCAGTTATTTGGTGGTAGTGGAAACGATAAATTGAG
TGGAGGGGATGGTAATAATTATCTGACAGGAGGAAGCGGTAATGATGAGCTTCAGGCACACGGAGCTTAT
AATATTCTGTCAGGTGGTACTGGTGATGATAAACTTTATGGTGGTGGTGGTATTGATCTTCTGGATGGAG
GGGAAGGTAATGACTATCTGAATGGTGGTTTTGGTAATGATATTTATGTTTATGGGCAAAACTATGGTCA
TCATACAATTGCAGATGAAGGAGGTAAAGGAGATCGTTTGCACTTATCTGATATTAGCTTTGATGATATC
GCATTTAAGAGAGTTGGAAATGATCTTATCATGAATAAAGCCATTAATGGTGTACTTTCATTTAATGAGT
CAAATGATGTCAATGGGATAACATTTAAAAACTGGTTTGCGAAAGATGCCTCAGGAGCAGATAATCATCT
TGTTGAGGTTATAACAGATAAAGATGGTCGAGAGATAAAAGTTGATAAGATACCTCATAATAATAATGAA
CGGTCAGGTTATATAAAAGCCAGTAATATAGCATCTGAAAAAAACATGGTTAATATCACCAGTGTTGCCA
ATGATATTAATAAGATTATTTCTTCAGTTTCAGGGTTCGATTCAGGTGATGAACGATTAGCATCTTTATA
TAATTTATCCTTACATCAAAACAACACACACTCAACAACTTTAACGACAACTGTCTG
Protein Sequence 
>gi|10955283|ref|NP_052624.1| hemolysin A [Escherichia coli O157:H7 str. Sakai] MTVNKIKNIFNNATLTTKSAFNTASSSVRSAGKKLILLIPDNYEAQGVGINELVKAADELGIEIHRTERDDTAIANQFFGAAEKVVGLTERGVAIFAPQLDKLLQKYQKVGSKIGGTAENVGNNLGKAGTVLSALQNFTGIALSGMALDELLRKQREGEDISQNDIAKSSIELINQLVDTVSSINSTVDSFSEQLNQLGSFLSSKPRLSSVGGKLQNLPDLGPLGDGLDVVSGILSAVSASFILGNSDAHTGTKAAAGIELTTQVLGNVGKAVSQYILAQRMAQGLSTTAASAGLITSAVMLAISPLSFLAAADKFERAKQLESYSERFKKLNYEGDALLAAFHKETGAIDAALTTINTVLSSVSAGVSAASSASLIGAPISMLVSALTGTISGILEASKQAMFEHVAEKFAARINEWEKEHGKNYFENGYDARHAAFLEDSLSLLADFSRQHAVERAVAITQQHWDEKIGELAGITRNADRSQSGKAYINYLENGGLLEAQPKEFTQQVFDPQKGTIDLSTGNVSSVLTFITPTFTPGEEVRERKQSGKYEYMTSLIVNGKDTWSVKGIKNHKGVYDYSKLIQFVEKNNKHYQARIISELGDKDDVVYSGAGSSEVFAGEGYDTVSYNKTDVGKLTIDATGASKPGEYIVSKNMYGDVKVLQEVVKEQEVSVGKRTEKIQYRDFEFRTGGIPYDVIDNLHSVEELIGGKHDDEFKGGKFNDIFHGADGNDYIEGNYGNDRLYGDDGDDYISGGQGDDQLFGGSGNDKLSGGDGNNYLTGGSGNDELQAHGAYNILSGGTGDDKLYGGGGIDLLDGGEGNDYLNGGFGNDIYVYGQNYGHHTIADEGGKGDRLHLSDISFDDIAFKRVGNDLIMNKAINGVLSFNESNDVNGITFKNWFAKDASGADNHLVEVITDKDGREIKVDKIPHNNNERSGYIKASNIASEKNMVNITSVANDINKIISSVSGFDSGDERLASLYNLSLHQNNTHSTTLTTTV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in zebra fish (Wiles et al., 2009).
References
Wiles et al., 2009: Wiles TJ, Bower JM, Redd MJ, Mulvey MA. Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS pathogens. 2009; 5(12); e1000697. [PubMed: 20019794].