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aslA from Escherichia coli str. K-12 substr. DH10B

Victor ID 2273
Gene Name aslA from Escherichia coli str. K-12 substr. DH10B
Sequence Strain (Species/Organism) Escherichia coli str. K-12 substr. DH10B
NCBI Gene ID 6061059
NCBI Protein GI 170083285
Locus Tag ECDH10B_3991
Protein Accession YP_001732605.1
Other Database IDs UniProtKB-ID: B1XAG9_ECODH
UniRef100: UniRef100_P25549
UniRef90: UniRef90_P25549
UniRef50: UniRef50_P25549
UniParc: UPI0000126109
EMBL: CP000948
EMBL-CDS: ACB04827.1
RefSeq_NT: NC_010473.1
EnsemblGenome: EBESCG00000012735.
EnsemblGenome_TRS: EBESCT00000013673
EnsemblGenome_PRO: EBESCP00000013201
GenomeReviews: CP000948_GR
KEGG: ecd:ECDH10B_3991
HOGENOM: HBG374065
OMA: PTRATIM
ProtClustDB: CLSK880785
BioCyc: ECOL316385:ECDH10B_3991-MONOMER
Taxonomy ID 316385
Gene Starting Position 4081294
Gene Ending Position 4082949
Gene Strand (Orientation) -
Protein Name acrylsulfatase-like enzyme
DNA Sequence 
>gi|170079663:4081294-4082949 Escherichia coli str. K-12 substr. DH10B, complete genome
CTTAGTCAGATTTAATCTGCGCGCGTGGTGGATATTTTTTCAGGATCTCCATATACGCGTGCATTTCGGT
CTGTAGCGGTACACCCATCGGAATATGGCGCACGCCGATGGAGTCGCTTTCCTGCGGATCGGTGTAGAGG
TTAAACACCGACGATCCCGCCGTTTGCATTACTGTGCCGGTGAATCCACCCTGATATCCGCTCTGGGTAT
AAGCGTAAGGTTGCTGAATCAGGACGTGATACTTGAACTCATCCATACGCACAGCAGCGAGTTTACCGTT
GAGGAAGTAGTGCTCGGCCTTACGGTTAGACTGACCATTTGTTCCCAGGAAGAAGGATGTCTGGTCCACA
CCATCGATAAAGGTGGTTTTCGGCACTAAATTCGCCACTTTCGCTCCAGGATGCCCTGCCAGATCCAGCG
CGGTAGGGAAGAGATCTGCCAGATCGACAATACCGTCAGATTTACGCGGTTGGATCATCCCTTTCCAGTA
AACGAAAGTCGGTACGCGAACGCCGCCTTCCCAGGTCGAACCTTTCGCACCACGGAACGGGGTGCGTCCG
TGCGGCGGTACTTCGGCTTCCGGTCCGTTATCGGAGGTAAAGACGATCAGCGTGTTATCAAGCTGACCGT
TTTTCTCCAGTGTTTTATACAGATTAGCGAACACATCGTTCATCTCCACCATGCAGTCGCCATACGAGGT
GCGTGCCGGAGAGCTACCCGCATATTTCGCATTTGGGTAGTTATCGAAGTGGCAGCCACGAGTGCCGTAG
TAGAGGAAGAATGGTTTATCGCTCTTCGCCATCTTGTCGAGGAACTTAACGCCATAGTCCATCCAGCGTT
GATCCAGATCTTCCATATATTTCGGCGTAATGTCGGCAATGGCCTGTTGTTCGCCGCCGCGCACCGCATG
AACGTCATCTTTGCTGAACGGTAATTGCTTGATGTATTCAGAACGGTCCGGACTCAGGGCCACTTCCGGA
TTGACGTGAACGTCGCGCCATTCGGTGTACATATCAGACACCGAGTTAAAGCCACGGAAATCATCAAAGC
CAACGTTCTGCGGCTGCGACTCTTTGTTTTCCCCCATATGCCATTTTCCGATGGCCTGAGTGACGTAGCC
CTGATCGTGCAGCAACTGCGGCAGCGTGGTTAACCCTTGCAGCCCGCCCGGTTGCCCGTACATTGGCGGC
ATCAGAATGCCGTGGTGGATGGAGTATTGTCCGGTGAGAATGGTGGCGCGGGTTGGGGAAGAGCTTGGTT
GAGAATACGCCGAAGTTAAAATCAGCCCCTGGCTGGCAACGGCGTCGATATCTGGTGTAGGGTTACCCAC
CGCCACGCCGCCACCGTTAAAACCGACGTCCATCCAGCCCACATCGTCCAGCAAGAAAACAACCACATTC
GGTTTCTTACCGGTTTTTTTCTCAAGTTCTGCCAGCTTCTGCTGGGTTTCTTTATCCTGCGCCGGATGCT
GCATTACTGGCATCATATTGTCGGCAATAGTGGTCGCCGGTTTAACCAGATACTGGTTTGGGTGATCGTA
TCCGGCAAAGCCTTTGCGTGCGGTGGCAGTTGACGGGGTATCTGCTGCGCTGGCCATGAGAGGAAGAGCG
GCGGCGACAGCAACAACAAGACGTTTGGGTGAAAACGAAAATTCCA
Protein Sequence 
>gi|170083285|ref|YP_001732605.1| acrylsulfatase-like protein [Escherichia coli str. K-12 substr. DH10B] MEFSFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWMDYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFANLYKTLEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: disruption mutant was less invasive in an in vitro HBMEC invasion assay than the wild-type E. coli K1 (Hoffman et al., 2000).
COG COG3119P, under P: Inorganic ion transport and metabolism
References
Hoffman et al., 2000: Hoffman JA, Badger JL, Zhang Y, Huang SH, Kim KS. Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo. Infection and immunity. 2000; 68(9); 5062-5067. [PubMed: 10948126].