Victors

dppA from Escherichia coli str. K-12 substr. DH10B
Victor ID	2270
Gene Name	dppA from Escherichia coli str. K-12 substr. DH10B
Sequence Strain (Species/Organism)	Escherichia coli str. K-12 substr. DH10B
NCBI Gene ID	6058698
NCBI Protein GI	170083053
Locus Tag	ECDH10B_3723
Protein Accession	YP_001732373.1
Other Database IDs	UniProtKB-ID: B1X8G0_ECODH UniRef100: UniRef100_P23847 UniRef90: UniRef90_P23847 UniRef50: UniRef50_P23847 UniParc: UPI0000129845 EMBL: CP000948 EMBL-CDS: ACB04595.1 RefSeq_NT: NC_010473.1 EnsemblGenome: EBESCG00000009342. EnsemblGenome_TRS: EBESCT00000010280 EnsemblGenome_PRO: EBESCP00000009808 GenomeReviews: CP000948_GR KEGG: ecd:ECDH10B_3723 HOGENOM: HBG688042 OMA: TVELWAM ProtClustDB: CLSK880713 BioCyc: ECOL316385:ECDH10B_3723-MONOMER
Taxonomy ID	316385
Gene Starting Position	3801865
Gene Ending Position	3803472
Gene Strand (Orientation)	-
Protein Name	dipeptide transporter; periplasmic-binding component of ABC superfamily
DNA Sequence	>gi\|170079663:3801865-3803472 Escherichia coli str. K-12 substr. DH10B, complete genome ATTATTCGATAGAGACGTTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT ACGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACCACCTGC GCTTGTTTGTACAGTTCAACGCGTTTATTGTGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGGGTGGCGAA GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGGTGCTCGCCATCTTTCGCA CGCTTGAGGTACTCACCCCATTCGTAGGTGACAATTTTGGCCTGCACGCCGACTTTCGCCCAGTCTGCCT GAATCATCTCCGCCATGCGGCGAGCGTTCGGGTTATACGGACGTTGTACCGGCATCGCCCACAGGTCGAT GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAGGTGTAGTCC TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACGCCCGCGCCCTGAT AAACCGCTTTGATGATCGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCGAG TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACGTTCAGCCCCGGCATTTCCATCAGATTGATGGAT TTATCCTGCTTCATGCGAGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCATTCTTCTGCA ATTTCGCGTAACGCACGGAAGCGTCAGGGGTAATAGAGAAAACCAGCGTATCGATCTGCGGTTTGGTGCC CCAGTAGCCATCAAACGCTTTGTAGCGGATACGGGAATCTTTTTGATACTGCTGTAACTGGAACGGACCG GTTCCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCATCAGCATATTCTTTTG ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACAAACTG AACGGTGTTGTCGTCCACCTTTTTCACTTCACTGATCAGCTCTGGCAAGCCCATGCCTTCGAAGTATTCG TAGCTGCCGCCAGAAACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACCACAT CATCGGCGTTCAGTTCACGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGGATCACTTCGGTGGTG CCGATTTTAAATTCAACCAGACGGTTATAAAGCGGGACGGAAGAGGCGTCATAGGTGGTGCCGGAGGTAA ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence	>gi\|170083053\|ref\|YP_001732373.1\| peptide ABC transporter periplasmic substrate-binding protein [Escherichia coli str. K-12 substr. DH10B] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG	COG0747E, under E: Amino acid transport and metabolism
References	*Haugen et al., 2007:* Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].


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dppA from Escherichia coli str. K-12 substr. DH10B