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sugC

Victor ID 227
Gene Name sugC
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887104
NCBI Protein GI 15608378
Locus Tag Rv1238
Protein Accession NP_215754.1
Other Database IDs UniProtKB-ID: O50454_MYCTU
UniRef100: UniRef100_A5U1T6
UniRef90: UniRef90_A5U1T6
UniRef50: UniRef50_D1A2U2
UniParc: UPI00000D5E10
EMBL: AE000516
EMBL: BX842575
EMBL-CDS: AAK45534.1
EMBL-CDS: CAA15894.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
HSSP: Q9YGA6
EnsemblGenome: EBMYCG00000002230.
EnsemblGenome_TRS: EBMYCT00000002232
EnsemblGenome_PRO: EBMYCP00000002232
EnsemblGenome: EBMYCG00000071594.
EnsemblGenome_TRS: EBMYCT00000071599
EnsemblGenome_PRO: EBMYCP00000069658
GenomeReviews: AE000516
Taxonomy ID 83332
Gene Starting Position 1380683
Gene Ending Position 1381864
Gene Strand (Orientation) +
Protein Name PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC
DNA Sequence 
>gi|57116681:1380683-1381864 Mycobacterium tuberculosis H37Rv, complete genome
GATGGCCGAGATTGTGTTGGACCACGTCAACAAGAGTTACCCCGACGGTCACACAGCGGTGCGCGACCTC
AACCTCACCATCGCCGACGGCGAATTTCTGATCCTGGTAGGGCCTTCCGGTTGTGGCAAGACCACGACGC
TGAATATGATTGCTGGGCTTGAAGATATCTCGTCGGGAGAACTGCGCATCGCCGGTGAGCGGGTAAACGA
GAAGGCGCCAAAGGACCGTGACATCGCGATGGTGTTCCAGTCGTACGCGCTTTACCCGCATATGACGGTG
CGCCAGAACATCGCGTTCCCGCTGACCCTGGCGAAGATGAGAAAGGCCGACATCGCGCAGAAGGTCTCCG
AGACTGCAAAAATCCTTGACCTGACCAACCTTCTGGATCGCAAGCCCTCACAATTGTCGGGTGGTCAGCG
ACAGCGGGTCGCGATGGGCAGGGCAATCGTGCGCCATCCCAAAGCATTCCTGATGGACGAGCCGCTGTCG
AACTTGGACGCGAAGTTGCGGGTCCAGATGCGCGGCGAGATTGCCCAGCTGCAGCGGAGGCTGGGTACCA
CCACCGTCTACGTCACCCACGACCAGACCGAGGCAATGACGCTGGGCGATCGCGTGGTAGTGATGTACGG
GGGCATCGCACAGCAGATCGGCACCCCTGAGGAGCTTTACGAACGGCCCGCCAATCTGTTTGTCGCGGGC
TTTATCGGCTCGCCGGCCATGAATTTCTTCCCTGCCAGGCTGACCGCGATCGGACTGACCCTGCCGTTCG
GTGAGGTGACGCTGGCCCCCGAAGTCCAGGGGGTGATCGCAGCGCACCCGAAACCGGAAAACGTCATCGT
AGGCGTGCGGCCGGAGCATATCCAGGACGCAGCATTGATCGACGCGTATCAACGCATCAGGGCGCTGACC
TTCCAGGTGAAGGTCAACTTGGTCGAGTCTTTAGGCGCCGACAAATATCTGTATTTCACTACCGAGAGCC
CGGCTGTGCACTCGGTTCAGTTGGACGAGTTGGCGGAGGTAGAGGGGGAGTCGGCGTTACACGAAAATCA
GTTCGTGGCAAGGGTTCCCGCCGAGTCCAAGGTAGCCATCGGGCAGTCGGTCGAGTTGGCTTTCGATACC
GCCAGACTTGCCGTCTTCGACGCCGACTCCGGTGCGAACCTGACCATTCCGCACCGCGCCTA
Protein Sequence 
>gi|15608378|ref|NP_215754.1| sugar ABC transporter ATP-binding protein SugC [Mycobacterium tuberculosis H37Rv] MAEIVLDHVNKSYPDGHTAVRDLNLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMRKADIAQKVSETAKILDLTNLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVQMRGEIAQLQRRLGTTTVYVTHDQTEAMTLGDRVVVMYGGIAQQIGTPEELYERPANLFVAGFIGSPAMNFFPARLTAIGLTLPFGEVTLAPEVQGVIAAHPKPENVIVGVRPEHIQDAALIDAYQRIRALTFQVKVNLVESLGADKYLYFTTESPAVHSVQLDELAEVEGESALHENQFVARVPAESKVAIGQSVELAFDTARLAVFDADSGANLTIPHRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003)
COG COG3839G, under G: Carbohydrate transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].