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aslA from Escherichia coli str. K-12 substr. MG1655

Victor ID 2266
Gene Name aslA from Escherichia coli str. K-12 substr. MG1655
Sequence Strain (Species/Organism) Escherichia coli str. K-12 substr. MG1655
NCBI Gene ID 949015
NCBI Protein GI 16131653
Locus Tag b3801
Protein Accession NP_418245.1
Other Database IDs UniProtKB-ID: ASLA_ECOLI
UniRef100: UniRef100_P25549
UniRef90: UniRef90_P25549
UniRef50: UniRef50_P25549
UniParc: UPI0000126109
EMBL: M90498
EMBL: M87049
EMBL: U00096
EMBL: AP009048
EMBL-CDS: AAC32036.1
EMBL-CDS: AAA67597.1
EMBL-CDS: AAC76804.1
EMBL-CDS: BAE77500.1
RefSeq_NT: AC_000091.1
RefSeq_NT: NC_000913.2
EnsemblGenome: EBESCG00000000468
EnsemblGenome_TRS: EBESCT00000000559
EnsemblGenome_PRO: EBESCP00000000559
EnsemblGenome: EBESCG00000016395
EnsemblGenome_TRS: EBESCT00000017339
EnsemblGeno
Taxonomy ID 511145
Gene Starting Position 3982374
Gene Ending Position 3984029
Gene Strand (Orientation) -
Protein Name acrylsulfatase-like enzyme
DNA Sequence 
>gi|49175990:3982374-3984029 Escherichia coli str. K-12 substr. MG1655 chromosome, complete genome
CTTAGTCAGATTTAATCTGCGCGCGTGGTGGATATTTTTTCAGGATCTCCATATACGCGTGCATTTCGGT
CTGTAGCGGTACACCCATCGGAATATGGCGCACGCCGATGGAGTCGCTTTCCTGCGGATCGGTGTAGAGG
TTAAACACCGACGATCCCGCCGTTTGCATTACTGTGCCGGTGAATCCACCCTGATATCCGCTCTGGGTAT
AAGCGTAAGGTTGCTGAATCAGGACGTGATACTTGAACTCATCCATACGCACAGCAGCGAGTTTACCGTT
GAGGAAGTAGTGCTCGGCCTTACGGTTAGACTGACCATTTGTTCCCAGGAAGAAGGATGTCTGGTCCACA
CCATCGATAAAGGTGGTTTTCGGCACTAAATTCGCCACTTTCGCTCCAGGATGCCCTGCCAGATCCAGCG
CGGTAGGGAAGAGATCTGCCAGATCGACAATACCGTCAGATTTACGCGGTTGGATCATCCCTTTCCAGTA
AACGAAAGTCGGTACGCGAACGCCGCCTTCCCAGGTCGAACCTTTCGCACCACGGAACGGGGTGCGTCCG
TGCGGCGGTACTTCGGCTTCCGGTCCGTTATCGGAGGTAAAGACGATCAGCGTGTTATCAAGCTGACCGT
TTTTCTCCAGTGTTTTATACAGATTAGCGAACACATCGTTCATCTCCACCATGCAGTCGCCATACGAGGT
GCGTGCCGGAGAGCTACCCGCATATTTCGCATTTGGGTAGTTATCGAAGTGGCAGCCACGAGTGCCGTAG
TAGAGGAAGAATGGTTTATCGCTCTTCGCCATCTTGTCGAGGAACTTAACGCCATAGTCCATCCAGCGTT
GATCCAGATCTTCCATATATTTCGGCGTAATGTCGGCAATGGCCTGTTGTTCGCCGCCGCGCACCGCATG
AACGTCATCTTTGCTGAACGGTAATTGCTTGATGTATTCAGAACGGTCCGGACTCAGGGCCACTTCCGGA
TTGACGTGAACGTCGCGCCATTCGGTGTACATATCAGACACCGAGTTAAAGCCACGGAAATCATCAAAGC
CAACGTTCTGCGGCTGCGACTCTTTGTTTTCCCCCATATGCCATTTTCCGATGGCCTGAGTGACGTAGCC
CTGATCGTGCAGCAACTGCGGCAGCGTGGTTAACCCTTGCAGCCCGCCCGGTTGCCCGTACATTGGCGGC
ATCAGAATGCCGTGGTGGATGGAGTATTGTCCGGTGAGAATGGTGGCGCGGGTTGGGGAAGAGCTTGGTT
GAGAATACGCCGAAGTTAAAATCAGCCCCTGGCTGGCAACGGCGTCGATATCTGGTGTAGGGTTACCCAC
CGCCACGCCGCCACCGTTAAAACCGACGTCCATCCAGCCCACATCGTCCAGCAAGAAAACAACCACATTC
GGTTTCTTACCGGTTTTTTTCTCAAGTTCTGCCAGCTTCTGCTGGGTTTCTTTATCCTGCGCCGGATGCT
GCATTACTGGCATCATATTGTCGGCAATAGTGGTCGCCGGTTTAACCAGATACTGGTTTGGGTGATCGTA
TCCGGCAAAGCCTTTGCGTGCGGTGGCAGTTGACGGGGTATCTGCTGCGCTGGCCATGAGAGGAAGAGCG
GCGGCGACAGCAACAACAAGACGTTTGGGTGAAAACGAAAATTCCA
Protein Sequence 
>gi|16131653|ref|NP_418245.1| putative Ser-type periplasmic non-aryl sulfatase [Escherichia coli str. K-12 substr. MG1655] MEFSFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWMDYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFANLYKTLEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: disruption mutant was less invasive in an in vitro HBMEC invasion assay than the wild-type E. coli K1 (Hoffman et al., 2000).
COG COG3119P, under P: Inorganic ion transport and metabolism
References
Hoffman et al., 2000: Hoffman JA, Badger JL, Zhang Y, Huang SH, Kim KS. Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo. Infection and immunity. 2000; 68(9); 5062-5067. [PubMed: 10948126].