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rfaL

Victor ID 2260
Gene Name rfaL
Sequence Strain (Species/Organism) Escherichia coli str. K-12 substr. MG1655
NCBI Gene ID 948148
NCBI Protein GI 16131493
Locus Tag b3622
Genbank Accession U00096
Protein Accession NP_418079
Other Database IDs UniProtKB-ID: RFAL_ECOLI
UniRef100: UniRef100_P27243
UniRef90: UniRef90_P27243
UniRef50: UniRef50_P27243
UniParc: UPI00001681D8
EMBL: M95398
EMBL: U00039
EMBL: U00096
EMBL: AP009048
EMBL-CDS: AAA24524.1
EMBL-CDS: AAB18599.1
EMBL-CDS: AAC76646.1
EMBL-CDS: BAE77670.1
RefSeq_NT: AC_000091.1
RefSeq_NT: NC_000913.2
DIP: DIP-10673N
MINT: MINT-1286025
TCDB: 9.B.67.5.1
EnsemblGenome: EBESCG00000003413
EnsemblGenome_TRS: EBESCT00000004178
EnsemblGenome_PRO: EBESCP00000004178
EnsemblGenome_TRS: EBESCT0000
Taxonomy ID 511145
Gene Starting Position 3794970
Gene Ending Position 3796229
Gene Strand (Orientation) +
Protein Name O-antigen ligase
Protein pI 9.92
Protein Weight 44891.56
Protein Length 419
Protein Note Also known as ECK3612; JW3597; waaLO-antigen ligase; lipopolysaccharide core biosynthesis
DNA Sequence 
>gi|49175990:3794970-3796229 Escherichia coli str. K-12 substr. MG1655 chromosome, complete genome
CATGCTAACATCCTTTAAACTTCATTCATTGAAACCTTACACTCTGAAATCATCAATGATTTTAGAGATA
ATAACTTATATATTATGTTTTTTTTCAATGATAATTGCATTCGTCGATAATACTTTCAGCATAAAAATAT
ATAATATCACTGCTATAGTTTGCTTATTGTCACTAATTTTACGTGGCAGACAAGAAAATTATAATATAAA
AAACCTTATTCTTCCCCTTTCTATATTTTTAATAGGCTTGCTTGATTTAATTTGGTATTCTGCGTTTAAA
GTAGATAATTCGCCATTTCGTGCTACTTACCATAGTTATTTAAATACTGCCAAAATATTTATATTTGGTT
CTTTTATTGTTTTCTTGACACTAACTAGCCAGCTAAAATCAAAAAAAGAGAGTGTATTATACACTTTGTA
TTCTCTGTCATTTCTAATTGCTGGATATGCAATGTATATTAATAGCATTCATGAAAATGACCGCATTTCT
TTTGGTGTAGGAACGGCAACAGGAGCAGCATATTCAACAATGCTAATAGGGATAGTTAGTGGCGTTGCGA
TTCTTTATACTAAGAAAAATCATCCTTTTTTATTTTTATTAAATAGTTGCGCGGTACTTTATGTTCTGGC
GCTAACACAAACCAGAGCAACCCTACTCCTGTTCCCTATAATTTGTGTTGCTGCATTAATAGCTTATTAT
AATAAATCACCCAAGAAATTCACTTCCTCTATTGTTCTACTAATTGCTATATTAGCTAGCATTGTTATTA
TATTTAATAAACCAATACAGAATCGCTATAATGAAGCATTAAATGACTTAAACAGTTATACCAATGCTAA
TAGTGTTACTTCCCTAGGTGCAAGACTGGCAATGTACGAAATTGGTTTAAATATATTCATAAAGTCACCT
TTTTCATTTAGATCAGCAGAGTCACGCGCTGAAAGTATGAATTTGTTAGTTGCAGAACACAATAGGCTAA
GAGGGGCATTGGAGTTTTCTAACGTACATCTACATAATGAGATAATTGAAGCAGGGTCACTGAAAGGTCT
GATGGGAATTTTTTCCACACTTTTCCTCTATTTTTCACTATTTTATATAGCATATAAAAAACGAGCTTTG
GGTTTGTTGATATTAACGCTTGGCATTGTGGGGATTGGACTCAGTGATGTGATCATATGGGCACGCAGCA
TTCCAATTATCATTATATCCGCTATAGTCCTCTTACTCGTCATTAATAATCGTAACAATACAATTAATTA
Protein Sequence 
>gi|16131493|ref|NP_418079.1| O-antigen ligase [Escherichia coli str. K-12 substr. MG1655]
MLTSFKLHSLKPYTLKSSMILEIITYILCFFSMIIAFVDNTFSIKIYNITAIVCLLSLILRGRQENYNIK
NLILPLSIFLIGLLDLIWYSAFKVDNSPFRATYHSYLNTAKIFIFGSFIVFLTLTSQLKSKKESVLYTLY
SLSFLIAGYAMYINSIHENDRISFGVGTATGAAYSTMLIGIVSGVAILYTKKNHPFLFLLNSCAVLYVLA
LTQTRATLLLFPIICVAALIAYYNKSPKKFTSSIVLLIAILASIVIIFNKPIQNRYNEALNDLNSYTNAN
SVTSLGARLAMYEIGLNIFIKSPFSFRSAESRAESMNLLVAEHNRLRGALEFSNVHLHNEIIEAGSLKGL
MGIFSTLFLYFSLFYIAYKKRALGLLILTLGIVGIGLSDVIIWARSIPIIIISAIVLLLVINNRNNTIN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rfaL mutant is attenuated in rats (Gonzalez et al., 2001).
COG COG3307M, under M: Cell wall/membrane/envelope biogenesis
References
Gonzalez et al., 2001: Gonzalez MD, Lichtensteiger CA, Vimr ER. Adaptation of signature-tagged mutagenesis to Escherichia coli K1 and the infant-rat model of invasive disease. FEMS microbiology letters. 2001; 198(2); 125-128. [PubMed: 11430402].