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cusC

Victor ID 2258
Gene Name cusC
Sequence Strain (Species/Organism) Escherichia coli str. K-12 substr. MG1655
NCBI Gene ID 946288
NCBI Protein GI 16128555
Locus Tag b0572
Genbank Accession U00096
Protein Accession NP_415104
Other Database IDs UniProtKB-ID: CUSC_ECOLI
UniRef100: UniRef100_P77211
UniRef90: UniRef90_Q8XBY3
UniRef50: UniRef50_Q8CWA4
UniParc: UPI00001286FC
EMBL: AF094824
EMBL: U82598
EMBL: U00096
EMBL: AP009048
EMBL: AF245661
EMBL-CDS: AAD30205.1
EMBL-CDS: AAB40770.1
EMBL-CDS: AAC73673.1
EMBL-CDS: BAA35206.1
EMBL-CDS: AAF70174.1
RefSeq_NT: AC_000091.1
RefSeq_NT: NC_000913.2
DIP: DIP-9347N
TCDB: 1.B.17.3.5
EnsemblGenome: EBESCG00000004088
EnsemblGenome_TRS: EBESCT00000005007
EnsemblGenome_PRO: EBESCP00000005007
EnsemblGeno
Taxonomy ID 511145
Gene Starting Position 594822
Gene Ending Position 596195
Gene Strand (Orientation) +
Protein Name copper/silver efflux system, outer membrane component
Protein pI 6.31
Protein Weight 48184.3
Protein Length 457
Protein Note Also known as ECK0564; ibeB; JW0561; silC; ylcB
DNA Sequence 
>gi|49175990:594822-596195 Escherichia coli str. K-12 substr. MG1655 chromosome, complete genome
TATGTCTCCTTGTAAACTTCTGCCATTTTGTGTGGCCCTTGCGCTAACCGGTTGTTCACTGGCACCGGAT
TATCAGCGTCCGGCAATGCCCGTGCCGCAGCAGTTCTCACTCAGCCAGAACGGCCTGGTTAACGCAGCAG
ATAACTATCAGAACGCGGGCTGGCGCACCTTTTTTGTTGATAATCAGGTGAAGACGCTGATTAGCGAGGC
GCTGGTGAATAATCGGGATTTGCGCATGGCGACGCTGAAAGTGCAGGAGGCACGGGCGCAATATCGTCTG
ACCGATGCCGACCGCTACCCACAGCTCAATGGCGAGGGCAGCGGCAGCTGGAGCGGTAATCTTAAAGGGA
ATACCGCCACGACACGGGAGTTTTCGACCGGCCTTAACGCCAGCTTTGACCTCGATTTTTTCGGTCGCTT
AAAGAACATGAGCGAAGCCGAGCGACAAAATTATTTAGCCACTGAGGAAGCTCAGCGCGCGGTGCATATT
CTGCTGGTTTCTAATGTCGCGCAAAGCTATTTCAATCAGCAACTGGCGTATGCGCAATTGCAAATAGCCG
AAGAAACGCTGCGTAATTATCAGCAGTCATATGCGTTTGTCGAAAAACAACTGTTGACAGGTAGCAGTAA
TGTTCTGGCGCTGGAACAGGCTCGCGGGGTGATAGAAAGTACCCGCAGCGACATCGCTAAACGTCAGGGG
GAACTGGCGCAGGCGAATAATGCATTGCAACTGTTGCTGGGAAGCTACGGCAAGCTGCCGCAAGCGCAGA
CAGTAAACAGCGACAGCCTGCAAAGCGTTAAATTACCGGCGGGATTGTCGTCGCAAATCTTATTGCAGCG
CCCGGATATTATGGAAGCTGAACACGCGTTAATGGCGGCTAATGCCAATATTGGCGCTGCACGCGCGGCA
TTTTTTCCGTCTATAAGCCTGACCAGCGGAATATCGACCGCCAGTAGCGATCTATCGTCATTATTTAACG
CCAGCAGCGGGATGTGGAATTTTATACCCAAAATTGAGATCCCCATTTTTAATGCCGGACGCAACCAGGC
CAATCTGGATATCGCCGAAATTCGCCAGCAGCAGTCGGTGGTGAATTATGAACAGAAAATCCAGAACGCC
TTTAAAGAAGTGGCAGATGCGCTGGCATTACGTCAAAGCCTGAACGATCAAATTAGCGCCCAGCAGCGTT
ATCTGGCATCGCTGCAAATTACTTTGCAACGGGCGCGGGCATTATATCAGCACGGCGCAGTAAGTTATCT
GGAAGTGCTGGATGCCGAGCGTTCTTTATTTGCAACCCGACAAACTTTACTTGATCTGAATTATGCCCGT
CAGGTTAACGAAATTTCTTTGTATACCGCACTTGGTGGCGGTTG
Protein Sequence 
>gi|16128555|ref|NP_415104.1| copper/silver efflux system, outer membrane component [Escherichia coli str. K-12 substr. MG1655]
MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVNAADNYQNAGWRTFFVDNQVKTLISEA
LVNNRDLRMATLKVQEARAQYRLTDADRYPQLNGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRL
KNMSEAERQNYLATEEAQRAVHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSN
VLALEQARGVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQILLQR
PDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQA
NLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYL
EVLDAERSLFATRQTLLDLNYARQVNEISLYTALGGG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ibeB mutant is unable to invade BMEC and was attenuated in a newborn rat model (Huang et al., 1999).
COG COG1538MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Huang et al., 1999: Huang SH, Chen YH, Fu Q, Stins M, Wang Y, Wass C, Kim KS. Identification and characterization of an Escherichia coli invasion gene locus, ibeB, required for penetration of brain microvascular endothelial cells. Infection and immunity. 1999; 67(5); 2103-2109. [PubMed: 10225861].