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ompA from Escherichia coli str. K-12 substr. MG1655

Victor ID 2256
Gene Name ompA from Escherichia coli str. K-12 substr. MG1655
Sequence Strain (Species/Organism) Escherichia coli str. K-12 substr. MG1655
NCBI Gene ID 945571
NCBI Protein GI 16128924
Locus Tag b0957
Protein Accession NP_415477.1
Other Database IDs UniProtKB-ID: OMPA_ECOLI
UniRef100: UniRef100_P0A911
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI0000130CF0
EMBL: V00307
EMBL: U00096
EMBL: AP009048
EMBL-CDS: CAA23588.1
EMBL-CDS: AAC74043.1
EMBL-CDS: BAA35715.1
RefSeq_NT: AC_000091.1
RefSeq_NT: NC_000913.2
PDB: 1BXW
PDB: 1G90
PDB: 1QJP
PDB: 2GE4
PDB: 2JMM
DIP: DIP-31879N
MINT: MINT-1308131
TCDB: 1.B.6.1.1
ECO2DBASE: F024.5
ECO2DBASE: F028.0
ECO2DBASE: F033.0
ECO2DBASE: F033.1
EnsemblGenome: EBESCG00000002090
EnsemblGenome_TR
Taxonomy ID 511145
Gene Starting Position 1018235
Gene Ending Position 1019275
Gene Strand (Orientation) -
Protein Name outer membrane protein A (3a;II*;G;d)
DNA Sequence 
>gi|49175990:1018235-1019275 Escherichia coli str. K-12 substr. MG1655 chromosome, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATACCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAGTCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATCTTGTCTGCCGGGATACCTTTGGAGATCAGGTAATCAACAACAGACTGAG
CACGGCGCTCGGACAGACCCTGGTTGTAAGCGTCAGAACCGATGCGGTCGGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGTTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCGTACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATGCCACCCAGACGAGTGTA
GATGTCCAGGTCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGTTGAACGCCCTGAGCTTTGTATGCA
CCGTTTTCAACGCTGCCTTTGTACGGCATACGACCTAACCAGTCGTAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGGCCATTGTTGTTGAT
GAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCA
Protein Sequence 
>gi|16128924|ref|NP_415477.1| outer membrane protein A (3a;II*;G;d) [Escherichia coli str. K-12 substr. MG1655] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].