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traT from Escherichia coli SMS-3-5

Victor ID 2255
Gene Name traT from Escherichia coli SMS-3-5
Sequence Strain (Species/Organism) Escherichia coli SMS-3-5
NCBI Gene ID 6106527
NCBI Protein GI 170650825
Locus Tag EcSMS35_A0012
Protein Accession YP_001739900.1
Other Database IDs UniProtKB-ID: B1LRJ3_ECOSM
UniRef100: UniRef100_Q6B3Y7
UniRef90: UniRef90_P15177
UniRef50: UniRef50_P15177
UniParc: UPI0000403470
EMBL: CP000971
EMBL-CDS: ACB20278.1
RefSeq_NT: NC_010488.1
EnsemblGenome: EBESCG00000064752.
EnsemblGenome_TRS: EBESCT00000065705
EnsemblGenome_PRO: EBESCP00000063187
GenomeReviews: CP000971_GR
KEGG: ecm:EcSMS35_A0012
HOGENOM: HBG320895
OMA: GITAYNS
ProtClustDB: PRK13731
BioCyc: ECOL439855:ECSMS35_A0012-MONOMER
Taxonomy ID 439855
Plasmid No pSMS35_130
Gene Starting Position 13547
Gene Ending Position 14278
Gene Strand (Orientation) -
Protein Name type IV secretion-like conjugative transfer system complement resistance protein TraT
DNA Sequence 
>gi|170650760:13547-14278 Escherichia coli SMS-3-5 plasmid pSMS35_130, complete sequence
ATCAGAGAATATTTGCGATTGATTTGGCCAGCTGGTCTTCGAGAACAGGCTTCGCCTCTTCAAATTTCAG
GTTAACCTTGTTCGCATTTGAGACCACACGGGTCTGGTATTTATGCTGGTTACCTGTTTCAGTACTGGTC
TGAATTTTCGCACCTGATGTGCCCTGACGCAGGGCGGCAACATTATCCGTTGTCACCGTTGCCTTAGTAC
GCTCTGCAATCTGCACATCCGTGATCATGGTATAGTTCACATCTTCCACCATCGCATCTGCAGCCATACC
CACCAGACCGGCAGCAAGGCCCACACCGAGTGTGGCACCGGCAGAATTGGAATTATATCCGGTGATACCG
GCACCTAACGCTGCACCAACTGCTGCGCCTTCATAACCACGGTTCAGCCATCCCTGAGACTCCCGCAGAT
CCATCTTATCGGCCTTCAGCACATTCGCCTGAATCCAGTAGTAGGCTTTATCCGGAGAAGTCACCACCTG
ATATCCTTTTGCTTTCACAGCATCAGCAATTTTGCCCTGCAGCCCACTCATGTCTTTATCAGACGTGTTT
TTGATCTGCAGAAATACCGTGCGTTCGCTGGCGGGTTCAAGCCAGATGGTCTCACTCATCTGAGTCTTCA
CCTCAAGGTTACGCTTCTTGATTGCTGTGCTCATCGCACCACACCCTGAAAGGGCCAGAGTGGAACTGAC
CAGTGCAACCATCATCAATTTTTTTGTTTTCA
Protein Sequence 
>gi|170650825|ref|YP_001739900.1| type IV secretion-like conjugative transfer system complement resistance protein TraT [Escherichia coli SMS-3-5] MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIWLEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKADKMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVEDVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNANKVNLKFEEAKPVLEDQLAKSIANIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: traT mutants have altered membrane permeability and are sensitive to hydrophobic antibiotics (Sukupolvi and O'Connor, 1987).
References
Sukupolvi and O'Connor, 1987: Sukupolvi S, O'Connor D. Amino acid alterations in a hydrophobic region of the TraT protein of R6-5 increase the outer membrane permeability of enteric bacteria. Molecular & general genetics : MGG. 1987; 210(1); 178-180. [PubMed: 3323837].