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iucC from Escherichia coli SMS-3-5

Victor ID 2253
Gene Name iucC from Escherichia coli SMS-3-5
Sequence Strain (Species/Organism) Escherichia coli SMS-3-5
NCBI Gene ID 6147083
NCBI Protein GI 170679922
Locus Tag EcSMS35_3180
Protein Accession YP_001745170.1
Other Database IDs UniProtKB-ID: B1LE79_ECOSM
UniRef100: UniRef100_B1LE79
UniRef90: UniRef90_Q47318
UniRef50: UniRef50_Q47318
UniParc: UPI00016A0CDC
EMBL: CP000970
EMBL-CDS: ACB15818.1
RefSeq_NT: NC_010498.1
EnsemblGenome: EBESCG00000061142.
EnsemblGenome_TRS: EBESCT00000062095
EnsemblGenome_PRO: EBESCP00000059737
GenomeReviews: CP000970_GR
KEGG: ecm:EcSMS35_3180
HOGENOM: HBG417345
OMA: PNPLYRA
ProtClustDB: CLSK888707
BioCyc: ECOL439855:ECSMS35_3180-MONOMER
Taxonomy ID 439855
Gene Starting Position 3260789
Gene Ending Position 3262531
Gene Strand (Orientation) -
Protein Name aerobactin siderophore biosynthesis protein IucC
DNA Sequence 
>gi|170679574:3260789-3262531 Escherichia coli SMS-3-5, complete genome
TTCATGATTCATATTCCTGAGTTACCAGCCACAGCGGATTTTGCAGATCCTCAAGGTAATTCGGCAGCAT
GCGGCTGCCGCCATCCAGATCAGGCCAGGTCAGTTTTACCGGGTTCAGCACCACGCGAATGATTTGTGGC
CTGAAAAGTGAGAAAAGCGCAAAACGCTCTGACATTTGTGGATGTTTTTTCATGTAATCACTCAACACTG
CTGCCAGCAGTTGATAAAATCGCCTTTCAGGTACGCCAAGACGAACCATCAGTGGCGAAATAAAACGCAG
TACTGTCACGAAGTGACCCGTCTGCAAATCATGGATTAAGTAGTCCGCACTCAGGCGGGATGTAACATCA
CGAACCTCCTGAGGCAAAGAGTCCATTTCGGGGAACTCTTCTTTCACCAGCCGCATATCGCCCTGGAAGT
CTTTCAGCAGAACACGCTGTGGAACCCCCTCTTTCATGGCGAGCGTTATATTTTGTCCATGTGCAATAAG
CGCGACACCGTAGCGGCAAAGCAGGTGATACAGAGGAACCACGACCACCCGGAACAGTTGCGTAAGCCAG
GTTTCAGCGTCCAGCCCGGAGCGGTCTATATATGCGCCTGCCAGCGGCTGATCGTTTTCGTCGCACTCCA
TCAGTGTTGCCATCAGAACCGGACTTTCATCCGGTTTCAGCCAGCGGCACGGATTCTCCCGCCAGATAAC
ACCAAGCATTTCCTGGTAGCGATAGGGAGCCCGGGCAAGCGCGGCATAGCCTTCATGGGAGACATAGCCT
GCAGCCGGTTCACCAAGGATCACTGCACCGCTTTGCACCAGGGTAGCGTCGGTCGCAAAAACCTGTTGTA
GCCAGCGTGAAGCCAGTGGTCCGGCAGCGATGTATCTGCCAGGAATCCCCCGGTAGCATGAGGTGTTGTA
GATGGTCAGAGGCAGCTTGATATCCAGCCCACCCCGGCGACTGGCGTTGGTCAGGGTACGCAGCGACTGC
TGGGCGAGCCACTGGTCGCCAAACTCGCCGAGAGACACCATCCTGCCTTCGGCAAAATCAGCGATGAAGT
CGGTGGCGATTTTTTGCTGCCACTGCCACGGATGTACAGGCAGCGGCAGCCAGTTATGATCCAGTCCGTT
TTCCTGCCAGACCTGACTGAAGCGGGCAAACTCCTGCGGATCCATTGCGGCCGTCAACAACTGATGAATA
TCCATCTCGTTATCACAGCGCCAGATCATATGTTCACGTTTTACCGCCAGCCAGTGCAGTCTAAAGGTGT
TGGCATACTCTGGCGCATATCGTTCCAGCGCCTCTTTACCCCAGCCACGGCGACCTTTATTAAAAACGAA
TTTAGGATGACCGCTCAGCAGGCATTGCAGGCGGTCGGCACTAAGATTAATCAGGTCACTGGCGCTCAGC
CCGCGACGGGCTTTCAGCAGTTGCAGGTCGCCCAGCAGCGTGGAATACAAATCCTGCATATGCTCAGCAA
CGGTTGCATCGCTCATTGACAGTACCTGCTTTAGCTGCATCAGCAGCGTCTGAGCCAGTACTGGCTCGTC
CGCGCAGCGCAGAGTTTGAGCATCAATCCAGAGCCAGCCCCAGATACCACGTTCAGCGATGAAGCGCCAT
TGTGCTCCCGGCAGGTTAATGCAGTAGCGGTCATCGCCCTGAGATTCCGCGTGGAAAACCTGCTCATACT
CCAGCTCAGACAACATTTTTGCCACCAGGCGGCGGTTGACCAAATCCCAGTCTTTGTGATTCA
Protein Sequence 
>gi|170679922|ref|YP_001745170.1| aerobactin siderophore biosynthesis protein IucC [Escherichia coli SMS-3-5] MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYSTLLGDLQLLKARRGLSASDLINLSADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENDQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (de and Martinez, 1988).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
de and Martinez, 1988: de Lorenzo V, Martinez JL. Aerobactin production as a virulence factor: a reevaluation. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1988; 7(5); 621-629. [PubMed: 2973985].