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aslA from Escherichia coli SMS-3-5

Victor ID 2249
Gene Name aslA from Escherichia coli SMS-3-5
Sequence Strain (Species/Organism) Escherichia coli SMS-3-5
NCBI Gene ID 6146022
NCBI Protein GI 170681296
Locus Tag EcSMS35_4166
Protein Accession YP_001746117.1
Other Database IDs UniProtKB-ID: B1LLX1_ECOSM
UniRef100: UniRef100_B1LLX1
UniRef90: UniRef90_P25549
UniRef50: UniRef50_P25549
UniParc: UPI00016A13B8
EMBL: CP000970
EMBL-CDS: ACB17192.1
RefSeq_NT: NC_010498.1
EnsemblGenome: EBESCG00000060453.
EnsemblGenome_TRS: EBESCT00000061406
EnsemblGenome_PRO: EBESCP00000059048
GenomeReviews: CP000970_GR
KEGG: ecm:EcSMS35_4166
HOGENOM: HBG374065
OMA: PTRATIM
ProtClustDB: CLSK880785
BioCyc: ECOL439855:ECSMS35_4166-MONOMER
Taxonomy ID 439855
Gene Starting Position 4263997
Gene Ending Position 4265652
Gene Strand (Orientation) -
Protein Name arylsulfatase
DNA Sequence 
>gi|170679574:4263997-4265652 Escherichia coli SMS-3-5, complete genome
CTTAGTCAGATTTAATCTGCGCGCGTGGTGGATATTTTTTCAGGATCTCCATATACGCGTGCATTTCGGT
CTGTAGCGGTACACCCATCGGAATATGGCGCACGCCGATGGAGTCGCTTTCCTGCGGATCGGTGTACAGG
TTAAACACCGACGATCCCGCCGTTTGCATTACTGTGCCGGTGAATCCACCCTGATACCCGCTCTGGGTAT
ACGCGTACGGTTGCTGGATCAGGACGTGATACTTGAACTCATCCATACGCACAGCAGAAAGTTTACCGTT
GAGGAAGTAGTGCTCGGCCTTACGGTTAGACTGACCATTTGTTCCCAGGAAGAAAGATGTCTGGTCCACA
CCATCGATAAAGGTGGTTTTCGGTACTAAATTCGCTACCTTCGCCCCAGGATGCCCCGCCAGATCCAGCG
CCGTAGGGAAGAGATCCGCCAGATCGACAATGCCGTCAGATTTACGCGGTTGGATCATGCCTTTCCAGTA
AACGAAGGTTGGCACACGAACGCCGCCTTCCCATGTAGAACCTTTCGCACCGCGGAACGGCGTGCGACCG
TGCGGCGGAACTTCGGCTTCCGGACCGTTATCAGAGGTGAACACAATCAGCGTGTTATCAAGCTGACCGT
TTTTCTCCAGTGCTTTATACAGATTGGCGAAGATATCGTTCATCTCCACCATGCAGTCGCCGTAAGAGGT
GCGCGCCGGAGAGCTACCCGCATATTTCGCATTTGGGTAGTTATCGAAGTGACAGCCGCGAGTGCCGTAG
TAGAGGAAGAAAGGCTTATCGCTCTTCGCCATCTTGTCGAGGAACTTAACGCCATATTCCATCCAGCGTT
GATCCAGGTCTTCCATATATTTCGGCGTAATGTCGGCAATGGCTTCCTGTTCACCGCCGCGCACGGCATG
AACGTCATCTTTGCTGAACGGCAGTTTTTGGATGTATTCAGAACGATCCGGGCTCAGGGCGACTTCCGGG
TTGACGTGAACATCACGCCATTCGGTATACATATCGGATACCGAGTTAAAGCCGCGGAAATCATCAAAGC
CAACGTTCTGCGGCTGCGACTCTTTGTTTTCCCCCATATGCCATTTCCCGATGGCCTGAGTGACGTAGCC
CTGATCGTGCAGCAACTGCGGCAGAGTGGTTAACCCTTGCAGACCGCCCGGTTGCCCGTACATTGGCGGC
ATCAGAATGCCGTGGTGGATGGAGTATTGTCCGGTAAGAATCGTGGCGCGGGTTGGGGAAGAACTCGGTT
GAGAATACGCCGAAGTTAAAATCAGCCCCTGGCTGGCAACGGCGTCGATATCTGGTGTAGGGTTACCCAC
CGCCACGCCGCCGCCGTTAAAGCCAACATCCATCCAGCCCACATCATCCAGCAAGAAAACAACCACGTTC
GGTTTCTTACCGGTTTTTTTCTCAAGTTCTGCCAGCTTCTGCTGGGTTTCTTTGTCTTGTGCAGGATGCT
GCATCACCGGCATCATGTTGTCGGCAATAGTGGTCGCCGGTTTAACCAGATACTGGTTTGGGTGATCGTA
TCCGGCAAAGCCTTTGCGTGCGGTGGCGGTTGACGGGGTATCTGCTGCGTTGGCCATGAGTGGAAGAGCG
GCGGCGACAGCTACAACAAGAAGTTTGGGTGAAAACGAAAATTCCA
Protein Sequence 
>gi|170681296|ref|YP_001746117.1| arylsulfatase [Escherichia coli SMS-3-5] MEFSFSPKLLVVAVAAALPLMANAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPDRSEYIQKLPFSKDDVHAVRGGEQEAIADITPKYMEDLDQRWMEYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDIFANLYKALEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLSAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: disruption mutant was less invasive in an in vitro HBMEC invasion assay than the wild-type E. coli K1 (Hoffman et al., 2000).
COG COG3119P, under P: Inorganic ion transport and metabolism
References
Hoffman et al., 2000: Hoffman JA, Badger JL, Zhang Y, Huang SH, Kim KS. Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo. Infection and immunity. 2000; 68(9); 5062-5067. [PubMed: 10948126].