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iucA from Escherichia coli SMS-3-5

Victor ID 2248
Gene Name iucA from Escherichia coli SMS-3-5
Sequence Strain (Species/Organism) Escherichia coli SMS-3-5
NCBI Gene ID 6145998
NCBI Protein GI 170683655
Locus Tag EcSMS35_3182
Protein Accession YP_001745172.1
Other Database IDs UniProtKB-ID: B1LE81_ECOSM
UniRef100: UniRef100_B7JCC1
UniRef90: UniRef90_Q47316
UniRef50: UniRef50_Q47316
UniParc: UPI0000505218
EMBL: CP000970
EMBL-CDS: ACB19551.1
RefSeq_NT: NC_010498.1
EnsemblGenome: EBESCG00000064216.
EnsemblGenome_TRS: EBESCT00000065169
EnsemblGenome_PRO: EBESCP00000062811
GenomeReviews: CP000970_GR
KEGG: ecm:EcSMS35_3182
HOGENOM: HBG578705
OMA: SFLNCYL
ProtClustDB: CLSK908239
BioCyc: ECOL439855:ECSMS35_3182-MONOMER
Taxonomy ID 439855
Gene Starting Position 3263479
Gene Ending Position 3265203
Gene Strand (Orientation) -
Protein Name aerobactin siderophore biosynthesis protein IucA
DNA Sequence 
>gi|170679574:3263479-3265203 Escherichia coli SMS-3-5, complete genome
TTCAGACCTCCTGAGCCTGCAGCGGGTTAGCGAAATCAAAATAGATCACCGAAGGGTCAACGATGGTGTT
CTCGTTATGATCGTTCAGATAACAGAAAAAGTTACCTTTTACGTTCCAGTACGGACTTTCCAGAACATAG
TTGAGACAGGTTTTATGAGTCACCTGGTCACGCACTTCAGCCAGCAATGTTCGTACACGAGCCATCAGAT
TCGCTTCGCTGTCCAGCCCGGCAGCACCCAGCGCAGCAGTTACGGCAAAAGTGGAGTTAACCAGCAGGTA
ATAAGGGAAATAGCGCAGCAACTGCTCACGGGTGAAAATATTTTCCGCCTGCGCCTCGTCAATGGTATCG
AGCCACTCTGTCGCGTGAGGCATAAACGCGCTGCCCTGGCAGTCACGGTAAATAAATCCGACCGGCAGAT
CCCCAAGCATCTGCACAAGAATATTTTGCTGATGCGCCAGCAGCACCAGGCCGTAATCCGCTTCAGCCGT
AAACAGAGGCTTCAGCACCTGCTGACAGTAAGCATCGACCCATGCGTGGGCGGCCTGTTGCACAGTGATA
CCGAGGCGATCGCTCAGGCGTTTTACCGCCGAAACCAGCAGCGAATCACCGCCATCCGGTGCGGCCTGAG
TCAGGGAAACCAGAACGTTGGTCTGGCTTTGCGGCTGCTCCAGCAGCAGGTTTTCACGCAGGGAAAACAA
ACTTTCCTGCATGATGTTGCCGTTAAGATCGCGCAGCCCGGCCCAGCCGTCCTCCTGCATTACCCGGAAA
GTAGGGAAGCGGGCCTGTAGCATCTGCCAGCCGTCGGTTTGCGCCAGACGTGCCAGGCGCATTCCTCGCT
CCACCTCTTTCACAGACAGAGTACGGACGGAGTTGGTCAGCCGAACGCTCAGGGAGAACTTGATCATATC
GCGGCTGGTAGCACAGTAGAGAGAGCGGGAAGAGGTGGTCGGCAGCCACGACGTGCCGGCCTCGCCTAAG
TCTCTGATAAGTCCTTTAGCAAAAAGTGCCTGGCACCACACCTGCTGCAAAAGATATTCTCCCTGCCACG
GGTGCAGCGGGAACAGCCATTGATTGTCACTTAATTCGTTGAGTAACTGGGGCGCATTTTCTGCGGCAAA
TCGCGTCAACCGCTGTTGAAGGTTAAGATGCAGACTTTCACCAGCGATTTGCGTTTTATCCACCGAAAAC
CACCGCAGCGGGAAGTGAGGTGCCATGTCAGGCAGGTATCGTTCAGCTTCCTGGCGGTTAAACGGTTCAT
GAGACTTAGGTGCAGGGTGGAAAGCGTGTCCTGTCAGCAGTGCCTGCTCAGCCTCGCCAAAATTCAACGC
TTTCTCACGCAGGATGGCCCAGTCATGGCGGGCATCAATTGTCTGTTGCGTATGGGCGTAGCTTTCCAGC
ACGCGTTGGTGGAAAGTTTCGCAGAGGGGAACTGGCAGAAAAAGTTGATGCCGGAGCTTGTCAATAATAA
GCCGGGAGAGAGTGGTAAAATCGACAGGATAACTGCCTGATGCCGTGACCAGATGAGCAGGAAATGCAAA
GCGGTGATGCTGGGTTGGGGAGAAATAAGCCACTCTGAAATGGAGCGACTTCTGTTCGTCCAGCGGGATA
ATCAATTCGTCTGGCGGGTATTCCGCCAGTTGCCAGTCTTTGGTTTCACGAATCAAGGCATTCAGGAAGC
ACTGCGCAGCCACATCTGTGGCGGATTTTTCAGAGGGCAGGATCA
Protein Sequence 
>gi|170683655|ref|YP_001745172.1| aerobactin siderophore biosynthesis protein IucA [Escherichia coli SMS-3-5] MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDLNGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (de and Martinez, 1988).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
de and Martinez, 1988: de Lorenzo V, Martinez JL. Aerobactin production as a virulence factor: a reevaluation. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1988; 7(5); 621-629. [PubMed: 2973985].