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dppA from Escherichia coli SMS-3-5

Victor ID 2243
Gene Name dppA from Escherichia coli SMS-3-5
Sequence Strain (Species/Organism) Escherichia coli SMS-3-5
NCBI Gene ID 6144283
NCBI Protein GI 170679624
Locus Tag EcSMS35_3863
Protein Accession YP_001745830.1
Other Database IDs UniProtKB-ID: B1LJA4_ECOSM
UniRef100: UniRef100_E2QGQ2
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI00000E4A94
EMBL: CP000970
EMBL-CDS: ACB15520.1
RefSeq_NT: NC_010498.1
EnsemblGenome: EBESCG00000060634.
EnsemblGenome_TRS: EBESCT00000061587
EnsemblGenome_PRO: EBESCP00000059229
GenomeReviews: CP000970_GR
KEGG: ecm:EcSMS35_3863
HOGENOM: HBG688042
OMA: TVELWAM
ProtClustDB: CLSK880713
BioCyc: ECOL439855:ECSMS35_3863-MONOMER
Taxonomy ID 439855
Gene Starting Position 3932412
Gene Ending Position 3934019
Gene Strand (Orientation) -
Protein Name dipeptide ABC transporter, periplasmic dipeptide-binding protein
DNA Sequence 
>gi|170679574:3932412-3934019 Escherichia coli SMS-3-5, complete genome
ATTATTCGATAGAGACATTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACGACCTGT
GCTTGTTTGTACAGTTCAACACGTTTATTGTGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGGGTGGCGAA
GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGATGCTCGCCATCTTTCGCA
CGCTTGAGGTACTCACCCCATTCGTAGGTGACGATTTTGGCCTGCACGCCGACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCGTTCGGGTTATACGGACGTTGTACCGGCATTGCCCACAAGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAAGTGTAGTCC
TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACGCCCGCGCCCTGAT
AAACTGCTTTGATGATGGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCCAG
TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACATTCAGCCCCGGCATTTCCATCAGGTTGATGGAT
TTATCCTGCTTCATGCGGGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCGTTCTTCTGCA
ATTTCGCGTAACGCACGGAAGCGTCAGGAGTAATAGAGAAGACCAGCGTATCGATCTTCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTATAGCGAATACGGGAATCTTTCTGGTACTGCTGTAACTGGAACGGGCCG
GTACCGATTGGGTTGAGATCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCGTCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACAAACTG
AACGGTGTTATCGTCCACCTTTTTCACTTCGCTGATCAGCTCCGGCAAGCCCATGCCTTCAAAGTATTCG
TAGCTGCCGCCAGAAACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACCACGT
CATCGGCGTTCAGTTCGCGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGGATCACTTCGGTGGTG
CCGATTTTAAATTCAACCAGGCGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTGGTACCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|170679624|ref|YP_001745830.1| dipeptide ABC transporter periplasmic dipeptide-binding protein [Escherichia coli SMS-3-5] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPKIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].