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manC

Victor ID 2235
Gene Name manC
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 962090
NCBI Protein GI 15802511
Locus Tag Z3195
Genbank Accession AE005174
Protein Accession NP_288537
Other Database IDs UniProtKB-ID: MANC2_ECO57
UniRef100: UniRef100_O85342
UniRef90: UniRef90_O85342
UniRef50: UniRef50_O85342
UniParc: UPI000012EB94
EMBL: AF061251
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAC32348.1
EMBL-CDS: AAG57091.1
EMBL-CDS: BAB36259.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000025157
EnsemblGenome_TRS: EBESCT00000026104
EnsemblGenome_PRO: EBESCP00000024997
EnsemblGenome: EBESCG00000055850
EnsemblGenome_TRS: EBESCT00000056802
EnsemblGenome_PRO: EBESCP00000054630
Gen
Taxonomy ID 155864
Gene Starting Position 2847047
Gene Ending Position 2848495
Gene Strand (Orientation) -
Protein Name mannose-1-P guanosyltransferase
Protein pI 6.25
Protein Weight 50697.89
Protein Length 482
DNA Sequence 
>gi|16445223:2847047-2848495 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
GTTAATCTTCATGTTTGTAACGTTCTTTCTGTCTTATAATATCATCCTCTCCCAAATAATCCCCTGAACT
GACTTCAATAAGATTAAGAGGGATTATGCCCGGATTCTCAAGACTATACGCTGCGCCAAGGGGAATGTAT
ATCGATTCATTTGCGGTGACTAGTTTAGTTTTATCGCCAAGGGTTACTTTTGCTGTACCAGAAAGCACGA
TCCAATGTTCAGAACGATGGTGATGCATCCTTAAAGAAAGCCCCTCACCAGGTTTCACAATAATTTTCTT
GACTTTGTATCGCTCACCTTGGTCAATCGAATCAAATTTTCCCCATGGTCGGAAAACTTCACGATGACTA
ATATACTCTGTACGTTGCTGCAATTTAAGCATTTCGACTATTTTTTTTACATGCTGTACATCACTCTTTT
TAGACACAAGAACGGCATCTTTAGTTTGCACGATAACCATATCTTCAATTCCAATGGCGGCTACCAACGC
TGACTCAGAGTAGATATAATTATTCTTAGTATCATAGGTTAATATATCACCTTTACATACATCTCCTGTT
TTCGATTTTAGACTAATGTCCCATAACGATTGCCAAGATCCAACGTCACTCCAACCAATATCAACAGGGC
ATACAACACATTTTTCTGTTTTTTCCATTACAGCAAAATCAATAGATTCAGCAGGACAATCTTGAAATTG
TTCTTTTGATAATCGAATAAAATCTAGATCAATGTATGAGGATGAGGCAACCTGTTCACAAACATTGTAA
ATGTCAGGTCTAAATTTTCTCAATTCCTCAAGATAAACAGATGCCTTAAACATGAATATTCCACTATTCC
AATAGTGATTACCAGAAGTCATATACAATTCTGCGGTTTCACGATTAGGCTTTTCGACAAACTTATTTAC
ATAATAAAAACCAGTATTTTCATGCCCTTGAAGCGGTACAGATAGTTCACCTCTCTCAATATACCCATAA
CCAGTTTCAGCATATTCTGGTATAATTCCAAACGTTACAATTTTACCTTGATTAGCGATGGGAGTTGCAT
TTTTAATAGCATCACAGAAAACACTTTCTTTAGCTATAACGTGGTCTGCCGCAAGAACTAGAAGCAATGG
ATCTTCCTGAGGATTACGTTTTAACGCATGAAACGCAGATATCGCTATTGCTGGTGCAGTATTTCGCCCG
CATGGTTCTAGAATAATATTACCATTTAATTTATTTATTTCCCTTAACTGTTCAGCCACAACAAAGCGAT
GCTGTTCATTTGTTATCACTAATGGTTTTTGACATGATAGGCCTGAAAGTCGTAGCAAAGTCGTTTGTAA
CAAGGTGTTATCACCAGAGAGTTGTAAAAACTGCTTTGGATATAGTTCACGAGAAAGTGGCCAAAGACGA
CTGCCTGTACCACCGGCCATAACTACAGCAATTATTGGCGCATCAGACA
Protein Sequence 
>gi|15802511|ref|NP_288537.1| mannose-1-P guanosyltransferase [Escherichia coli O157:H7 str. EDL933]
MSDAPIIAVVMAGGTGSRLWPLSRELYPKQFLQLSGDNTLLQTTLLRLSGLSCQKPLVITNEQHRFVVAE
QLREINKLNGNIILEPCGRNTAPAIAISAFHALKRNPQEDPLLLVLAADHVIAKESVFCDAIKNATPIAN
QGKIVTFGIIPEYAETGYGYIERGELSVPLQGHENTGFYYVNKFVEKPNRETAELYMTSGNHYWNSGIFM
FKASVYLEELRKFRPDIYNVCEQVASSSYIDLDFIRLSKEQFQDCPAESIDFAVMEKTEKCVVCPVDIGW
SDVGSWQSLWDISLKSKTGDVCKGDILTYDTKNNYIYSESALVAAIGIEDMVIVQTKDAVLVSKKSDVQH
VKKIVEMLKLQQRTEYISHREVFRPWGKFDSIDQGERYKVKKIIVKPGEGLSLRMHHHRSEHWIVLSGTA
KVTLGDKTKLVTANESIYIPLGAAYSLENPGIIPLNLIEVSSGDYLGEDDIIRQKERYKHED
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: manC mutant is attenuated in calves (Dziva et al., 2004).
COG COG0836M, under M: Cell wall/membrane/envelope biogenesis
References
Dziva et al., 2004: Dziva F, van Diemen PM, Stevens MP, Smith AJ, Wallis TS. Identification of Escherichia coli O157 : H7 genes influencing colonization of the bovine gastrointestinal tract using signature-tagged mutagenesis. Microbiology (Reading, England). 2004; 150(Pt 11); 3631-3645. [PubMed: 15528651].