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manB from Escherichia coli O157:H7 str. EDL933

Victor ID 2234
Gene Name manB from Escherichia coli O157:H7 str. EDL933
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 962089
NCBI Protein GI 15802510
Locus Tag Z3194
Protein Accession NP_288536.1
Other Database IDs UniProtKB-ID: MANB_ECO57
UniRef100: UniRef100_O85343
UniRef90: UniRef90_P37742
UniRef50: UniRef50_P37742
UniParc: UPI000012EB8A
EMBL: AF061251
EMBL: AB008676
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAC32349.1
EMBL-CDS: BAA77734.1
EMBL-CDS: AAG57090.1
EMBL-CDS: BAB36258.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000026231
EnsemblGenome_TRS: EBESCT00000027179
EnsemblGenome_PRO: EBESCP00000026072
EnsemblGenome: EBESCG00000056467
EnsemblGenome_TRS: EBESCT00000057419
Ensem
Taxonomy ID 155864
Gene Starting Position 2845673
Gene Ending Position 2847043
Gene Strand (Orientation) -
Protein Name phosphomannomutase
DNA Sequence 
>gi|16445223:2845673-2847043 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
ATCACTCACTTAGCAATTTAAGAAGAGCTTTAGTTTTCTTTTCCATTAGCTTTACATCACCGCGTGATTC
CACATTCAACCGCACCACCGGTTCGGTGTTGGAGGAGCGCAGGTTAAAGCGCCAGTCGGCAAAGGTCATG
CTGATGCCATCGGTGCGATCCACCGCCAGCGCCTCGCGGCTAAAATGCTGTTCCACGCGATTAATTGCCT
CAACGGGTTGCGCCAGTTTGCTGTTGATCTCACCGCTTGCCGGAAACGCCGCCATCCGGTCGCGCACCAT
TTCGCCCAGCGTTTTTCCTTTCAGGCACACCAGTTCGGCGACCAGCAGCCACGGGATCATGCCGCTGTCG
CAGTAAGCGAAATCACGGAAGTAATGGTGAGCGCTCATTTCGCCACCGTAGATGGCGTCTTCCTTGCGCA
TACGTTCTTTAATAAAGGCGTGTCCGGTTTTCGACATTACCGGGGTGCCGCCTGCGGCAGTCACCACATC
AACGGTGTTCCAGGAGAGACGTGGATCGTGGATGATCTTCGCGCCGGGATTTTTTTCGAGGAACGCTTCT
GCCAGCAGGCCGACAATGTAGTAGCCCTCGATAAACTGCCCTTTTTCGTCAAACAGGAAACAGCGGTCAA
AATCGCCATCAAAGGCAATGCCCATATCCGCGCCGTGTTTGATGACCGCATTACGGGTGTCGTCGCGGCA
TTCCGGCAGCAGCGGGTTAGGAATACCGTTGGGGAAATTGCCGTCCGGCGTGTTGTGTACTTTGATTAAT
TCCACCGGTGCGCCGAGGGCTTTAAATCGGGCTTCAATGGCGTCCACCACCGGACCCGCTGCGCCGTTCC
CGGAGTTGATCACCAGCTTGAGCGGCGTGAGGTTTTTGACGTTGATATAACCGAACAGGTGATCAACGTA
AGCGTCACGCAGATTGATTTGCTGATAGCGACCACGTTTGGTTTCATCGACAGGAGGGAAGTCATTGGCT
TCTGCCAGACGCTGGACATCGCGCAGTCCGGTATCACCGCTGATCGGGCGAGCCCCTTCGCGCACCAGCT
TCATGCCGTTGTAATCCATCGGGTTATGGCTGGCGGTAACTTCGATGCCGCCATCCACTCCGAGATGGAA
CGTGGCGAAATAGATCTCTTCGGTGCCGGACATACCGATATCCAGCACATCGACGCCCGCATCCTGTAAA
CCTTTCGCAAGCGCCAGTTTTAACGCTTCGCTGGTGAGGCGGACATCACCGCCTAAAACAATGGTTTTCG
GTTTGAGAAATTCGCCATAGGCACGCCCAATGCGCCAGGCAATATCTTCATTCAGTTCTTCGCCTAATTT
CCCGCGAATATCATAGGCTTTAAAGCAGGTTAAAGATTTCA
Protein Sequence 
>gi|15802510|ref|NP_288536.1| phosphomannomutase [Escherichia coli O157:H7 str. EDL933] MKSLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDVRLTSEALKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLFGYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGKTLGEMVRDRMAAFPASGEINSKLAQPVEAINRVEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVKLMEKKTKALLKLLSE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: manB mutant is attenuated in calves (Dziva et al., 2004).
COG COG1109G, under G: Carbohydrate transport and metabolism
References
Dziva et al., 2004: Dziva F, van Diemen PM, Stevens MP, Smith AJ, Wallis TS. Identification of Escherichia coli O157 : H7 genes influencing colonization of the bovine gastrointestinal tract using signature-tagged mutagenesis. Microbiology (Reading, England). 2004; 150(Pt 11); 3631-3645. [PubMed: 15528651].