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trkA

Victor ID 2221
Gene Name trkA
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 961474
NCBI Protein GI 15803817
Locus Tag Z4660
Genbank Accession AE005174
Protein Accession NP_289851
Other Database IDs UniProtKB-ID: TRKA_ECO57
UniRef100: UniRef100_P0AGJ0
UniRef90: UniRef90_P0AGJ0
UniRef50: UniRef50_P0A2K0
UniParc: UPI00001373C5
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG58411.1
EMBL-CDS: BAB37578.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000025277
EnsemblGenome_TRS: EBESCT00000026224
EnsemblGenome_PRO: EBESCP00000025117
EnsemblGenome: EBESCG00000058557
EnsemblGenome_TRS: EBESCT00000059510
EnsemblGenome_PRO: EBESCP00000057338
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 4238751
Gene Ending Position 4240127
Gene Strand (Orientation) +
Protein Name potassium transporter peripheral membrane component
Protein pI 5.79
Protein Weight 45804.65
Protein Length 458
Protein Note Also known as sapGinvolved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
DNA Sequence 
>gi|16445223:4238751-4240127 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
GATGAAAATTATCATTCTGGGTGCCGGCCAGGTTGGCGGCACACTGGCGGAAAACCTGGTTGGCGAGAAC
AACGATATCACTGTTGTCGATACCAACGGTGAGCGTCTGCGAACCTTGCAGGATAAATTTGACCTGCGAG
TCGTGCAGGGGCATGGCTCTCATCCACGCGTATTGCGGGAGGCAGGTGCCGACGACGCCGATATGCTGGT
TGCTGTAACCAGTTCAGATGAAACCAATATGGTTGCCTGCCAGGTAGCCTACTCACTTTTCAACACCCCT
AATCGCATCGCTCGTATCCGCTCACCAGACTACGTACGCGATGCCGATAAGCTATTTCATTCAGATGCTG
TACCGATTGATCATCTGATCGCACCAGAGCAGTTGGTTATCGATAATATTTACCGACTGATTGAGTATCC
CGGCGCATTGCAGGTGGTGAACTTCGCTGAGGGTAAAGTCAGCCTCGCTGTGGTTAAAGCCTATTATGGC
GGCCCGCTGATTGGTAATGCACTTTCGACCATGCGCGAACATATGCCACATATCGATACTCGTGTGGCAG
CAATTTTCCGCCACGATCGCCCCATTCGTCCGCAAGGTTCGACCATTGTTGAGGCTGGTGATGAAGTGTT
CTTTATTGCCGCTTCACAGCATATCCGCGCGGTGATGAGTGAATTACAGCGACTGGAAAAACCGTATAAG
CGGATCATGCTGGTTGGTGGCGGTAATATCGGTGCAGGGCTGGCGCGTCGTCTGGAAAAAGATTACAGCG
TTAAACTCATCGAACGTAATCAGCAGCGCGCTGCCGAACTGGCGGAAAAGTTGCAGAATACGATCGTCTT
TTTTGGTGATGCGTCGGATCAAGAACTGCTGGCCGAAGAACATATCGATCAAGTTGATCTGTTTATTGCC
GTCACCAACGATGACGAGGCCAATATCATGTCCGCCATGCTTGCCAAACGTATGGGTGCGAAAAAGGTGA
TGGTATTGATCCAGCGTCGCGCTTATGTGGATCTGGTTCAGGGGAGCGTGATCGATATTGCGATTTCACC
ACAACAAGCAACTATTTCTGCGTTGCTTAGCCATGTGCGAAAAGCAGATATTGTTGGTGTTTCCTCATTG
CGCCGCGGCGTAGCAGAAGCTATTGAAGCCGTTGCTCACGGTGATGAAAGCACCTCACGCGTTGTCGGCA
GAGTCATTGACGAAATCAAGCTACCGCCAGGAACGATTATTGGAGCGGTGGTACGTGGAAACGACGTGAT
GATTGCCAATGACAATCTGCGCATTGAGCAAGGCGATCACGTAATTATGTTCCTCACAGATAAAAAATTT
ATTACCGACGTCGAAAGACTCTTCCAGCCAAGCCCTTTCTTCTTGTA
Protein Sequence 
>gi|15803817|ref|NP_289851.1| potassium transporter peripheral membrane component [Escherichia coli O157:H7 str. EDL933]
MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFDLRVVQGHGSHPRVLREAGADDADMLV
AVTSSDETNMVACQVAYSLFNTPNRIARIRSPDYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYP
GALQVVNFAEGKVSLAVVKAYYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVF
FIAASQHIRAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQNTIVF
FGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISP
QQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRVIDEIKLPPGTIIGAVVRGNDVM
IANDNLRIEQGDHVIMFLTDKKFITDVERLFQPSPFFL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trkA mutant is attenuated in calves (van et al., 2005).
COG COG0569P, under P: Inorganic ion transport and metabolism
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].