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trpB

Victor ID 2219
Gene Name trpB
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 961399
NCBI Protein GI 15801917
Locus Tag Z2550
Genbank Accession AE005174
Protein Accession NP_287938
Other Database IDs UniProtKB-ID: TRPB_ECO57
UniRef100: UniRef100_B5YZP1
UniRef90: UniRef90_A7ZL79
UniRef50: UniRef50_P25269
UniParc: UPI000016543C
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG56555.1
EMBL-CDS: BAB35256.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000026548
EnsemblGenome_TRS: EBESCT00000027496
EnsemblGenome_PRO: EBESCP00000026389
EnsemblGenome: EBESCG00000055233
EnsemblGenome_TRS: EBESCT00000056185
EnsemblGenome_PRO: EBESCP00000054013
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 2267741
Gene Ending Position 2268934
Gene Strand (Orientation) +
Protein Name tryptophan synthase subunit beta
Protein pI 6.02
Protein Weight 41110.83
Protein Length 397
Protein Note catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
DNA Sequence 
>gi|16445223:2267741-2268934 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
AATGACAACATTACTTAACCCCTATTTTGGTGAGTTTGGCGGCATGTACGTGCCACAAATCCTGATGCCT
GCTCTGCGCCAGCTGGAAGAAGCTTTTGTCAGCGCGCAAAAAGATCCTGAATTTCAGGCTCAGTTCAACG
ACCTGCTGAAAAACTATGCCGGGCGTCCAACCGCGCTGACCAAATGCCAGAACATTACGGCTGGCACGAA
CACCACGCTGTATCTGAAGCGCGAAGATTTGCTGCACGGCGGCGCGCATAAAACTAACCAGGTGCTCGGT
CAGGCTTTACTGGCGAAGCGGATGGGTAAAACCGAAATCATCGCCGAAACCGGGGCCGGTCAGCATGGCG
TGGCGTCGGCCCTTGCCAGCGCCCTGCTCGGCCTGAAATGCCGTATTTATATGGGGGCCAAAGACGTTGA
ACGCCAGTCGCCTAACGTTTTTCGTATGCGTTTAATGGGTGCGGAAGTGATCCCGGTGCATAGCGGTTCC
GCGACGCTGAAAGATGCCTGTAACGAGGCGCTGCGCGACTGGTCCGGCAGTTATGAAACCGCGCACTATA
TGCTGGGCACCGCAGCTGGCCCACATCCTTATCCGACCATTGTCCGTGAGTTTCAGCGGATGATTGGCGA
AGAAACCAAAGCACAGATTCTGGAAAGAGAAGGTCGCCTGCCGGATGCCGTTATCGCCTGTGTTGGCGGC
GGTTCGAATGCCATCGGCATGTTTGCAGATTTCATCAACGAAACCAACGTCGGCCTGATTGGTGTGGAGC
CTGGTGGTCACGGTATCGAAACTGGCGAGCACGGCGCACCGCTAAAACATGGTCGCGTGGGTATCTATTT
CGGTATGAAAGCGCCGATGATGCAAACCGAAGACGGGCAGATTGAAGAATCTTACTCCATCTCCGCCGGA
CTCGATTTTCCGTCCGTCGGCCCACAACACGCGTATCTTAACAGCACTGGACGCGCTGATTATGTGTCAA
TTACCGATGATGAAGCACTGGAAGCCTTCAAAACGCTGTGCCTGCACGAAGGGATTATCCCGGCGCTGGA
ATCCTCCCACGCCCTGGCCCATGCGCTGAAAATGATGCGCGAAAACCCGGAAAAAGAGCAGCTACTGGTG
GTTAACCTTTCCGGTCGCGGCGATAAAGACATCTTCACCGTTCACGATATTTTGAAAGCACGAGGGGAAA
TCTG
Protein Sequence 
>gi|15801917|ref|NP_287938.1| tryptophan synthase subunit beta [Escherichia coli O157:H7 str. EDL933]
MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN
TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVE
RQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGE
ETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF
GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE
SSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trpB mutant is attenuated in calves (van et al., 2005).
COG COG0133E, under E: Amino acid transport and metabolism
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].