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dctA

Victor ID 2212
Gene Name dctA
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 961092
NCBI Protein GI 15804072
Locus Tag Z4942
Genbank Accession AE005174
Protein Accession NP_290108
Other Database IDs UniProtKB-ID: DCTA_ECO57
UniRef100: UniRef100_B5YVH5
UniRef90: UniRef90_B5BHQ7
UniRef50: UniRef50_B5BHQ7
UniParc: UPI000012901E
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG58669.1
EMBL-CDS: BAB37831.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000026010
EnsemblGenome_TRS: EBESCT00000026957
EnsemblGenome_PRO: EBESCP00000025850
EnsemblGenome: EBESCG00000055537
EnsemblGenome_TRS: EBESCT00000056489
EnsemblGenome_PRO: EBESCP00000054317
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 4491525
Gene Ending Position 4492811
Gene Strand (Orientation) -
Protein Name C4-dicarboxylate transporter DctA
Protein pI 9.06
Protein Weight 41241.8
Protein Length 428
Protein Note involved in the transport of C4-dicarboxylates across the membrane
DNA Sequence 
>gi|16445223:4491525-4492811 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
ATTAAGAGGATAATTCGTGCGTTTTGCCATCCGGCGCACGATTATTCAGCGCATCGTCCAGTTTTTTGTG
GTCCAGTTCTTTCACCCACTTAGCAACGACAATGGTCGCTACGCCGTTACCGACCAGGTTAGTCAGCGCA
CGAGCTTCTGACATAAAGCGGTCGATACCGAGGATCAGCGCCAGACCCGCTACCGGCAAATGGCCCACCG
CAGAGAGCGTCGCCGCCAGCACGATAAAGCCACTACCCGTTACCCCTGCCGCCCCTTTAGAAGAAAGCAG
CAACACGATTAACAGCGTGATTTGGTGGACGATATCCATCTGACTGTTAGTGGCCTGGGCGATAAACACC
GCCGCCATTGTCAGGTATATCGATGTGCCATCAAGGTTAAACGAGTAGCCTGTCGGGATGACCAGCCCCA
CCACCGATTTACGGCAGCCGAGTTTCTCCATCTTGTCGAGCATACGCGGCAGCGCCGACTCGGAAGATGA
AGTCCCCAGTACAATCAGCAGTTCTTCACGGATGTAGCGGATAAATTTGAAGATACTGAAACCAGTCGCT
TTAGCGATTGAACCCAATACCAGCACCACAAACAGGATACAGGTAATGTAGAAACAGATAATCAGCTGCC
CCAGTTGCACCAGTGTGCCGACGCCGTATTTACCGATGGTAAACGCCATTGCCCCGAACGCACCAATAGG
TGCCAGACGCATGATCATATTGATGATGCCGAAGATGACCTGCGAGAAACTTTCGATGACGTTAAAAATC
AGTTGGCCTTTGCTGCCCAGACGGTGGAGCGCAAAACCAAACAGTACGGCAAACAGCAGCACCTGCAGAA
TGTTACCGCTGGCAAATGCGCCAATGACGCTCGCCGGGATGACATCCATAATGAAGGCGACAATGCCCTG
GTCTTTCGCCTGATCGGCGTAAACCGCTACCGCTTTCGCATCAAGCGTTGCCGGATCGACGTTCATTCCG
GCACCAGGCTGCACGACGTTAACGATGATAAGACCAATAATCAGCGCGATGGTACTGACAATTTCAAAGT
AAAGCAGTGCGACTGCGCCGGTACGACCGACCGCCTTCATGCTTTCCATGCCCGCAATGCCCGTTACGAC
GGTACAAAAGATGACAGGAGCGATGATCATCTTAATGAGCTTAACGAAGCCGTCGCCAAGCGGTTTCATT
TGCTCGCCTATTTCAGGATAGAAATGGCCAAGGAGAATACCAATGGCTATCGCTGTCAGGACCTGAAAGT
AAAGGCTTTTAAACAGAGAGGTTTTCA
Protein Sequence 
>gi|15804072|ref|NP_290108.1| C4-dicarboxylate transporter DctA [Escherichia coli O157:H7 str. EDL933]
MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAV
GRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPAS
VIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGK
YGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKM
EKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSG
FIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDALNNRAPD
GKTHELSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dctA mutant is attenuated in calves (Dziva et al., 2004).
COG COG1301C, under C: Energy production and conversion
References
Dziva et al., 2004: Dziva F, van Diemen PM, Stevens MP, Smith AJ, Wallis TS. Identification of Escherichia coli O157 : H7 genes influencing colonization of the bovine gastrointestinal tract using signature-tagged mutagenesis. Microbiology (Reading, England). 2004; 150(Pt 11); 3631-3645. [PubMed: 15528651].