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dppA from Escherichia coli O157:H7 str. EDL933

Victor ID 2211
Gene Name dppA from Escherichia coli O157:H7 str. EDL933
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 961074
NCBI Protein GI 15804087
Locus Tag Z4961
Protein Accession NP_290125.1
Other Database IDs UniProtKB-ID: Q8X4K7_ECO57
UniRef100: UniRef100_Q8X4K7
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI0000165976
EMBL: AE005174
EMBL-CDS: AAG58688.1
RefSeq_NT: NC_002655.2
HSSP: P23847
EnsemblGenome: EBESCG00000026744.
EnsemblGenome_TRS: EBESCT00000027692
EnsemblGenome_PRO: EBESCP00000026585
GenomeReviews: AE005174_GR
KEGG: ece:Z4961
HOGENOM: HBG688042
OMA: TVELWAM
ProtClustDB: CLSK880713
Taxonomy ID 155864
Gene Starting Position 4515313
Gene Ending Position 4516920
Gene Strand (Orientation) -
Protein Name dipeptide transport protein
DNA Sequence 
>gi|16445223:4515313-4516920 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
ATTATTCGATAGAGACGTTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACCACCTGC
GCTTGCTTGTACAGTTCAACGCGTTTGTTATGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGAGTGGCGAA
GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGGTGCTCGCCATCTTTCGCA
CGCTTGAGGTACTCACCCCATTCGTAGGTGACAATTTTGGCCTGCACGCCGACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCGTTCGGGTTATACGGACGTTGTACCGGCATCGCCCACAGGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAGGTGTAGTCC
TGAAYGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACACCCGCGCCCTGAT
AAACCGCTTTGATGATCGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCGAG
TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACGTTCAGCCCCGGCATTTCCATCAGGTTGATAGAT
TTATCCTGCTTCATGCGGGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCATTTTTCTGCA
ATTTAGCGTAACGCACGGAAGCGTCAGGGGTAATAGAGAAAACCAGCGTATCGATCTGCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTGTAGCGGATACGGGAATCTTTTTGATACTGCTGTAACTGGAACGGACCG
GTGCCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCATCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACAAACTG
AACGGTGTTGTCGTCCACCTTTTTCACTTCGCTGATCAGCTCCGGCAAGCCCATGCCTTCGAAGTATTCG
TAGCTGCCGCCAGAAACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACCACGT
CATCGGCATTCATTTCGCGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGAATCACTTCGGTGGTG
CCGATTTTAAATTCAACTAGGCGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTGGTACCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|15804087|ref|NP_290125.1| dipeptide transport protein [Escherichia coli O157:H7 str. EDL933] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTREMNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDXQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].